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Setting up a kinase profiler with IMAP

inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimers disease. A property common to most cyclin-dependent kinase inhibitors? J Biol Chem 2001 276(1):25160.

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5. S.P. Davies, H. Reddy, M. Caivano, P. Cohen. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000 Oct 1;351(Pt 1):95105.

6. K. Godl, J. Wissing, A. Kurtenbach, P. Habenberger, S. Blencke, H. Gutbrod, K. Salassidis, M. Stein-Gerlach, A, Missio, M. Cotten, H. Daub. An efficient proteomics method to identify the cellular targets of protein kinase inhibitors. Proc Natl Acad Sci USA 2003 100(26):154349.

7. B. Thors, H. Halldorsson, G. Thorgeirsson. Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt. FEBS Lett 2004 573(1-3):17580.

8. H. Vankayalapati, D.J. Bearss, J.W. Saldanha, R.M. Munoz, S. Rojanala, D.D. Von Hoff, D. Mahadevan. Targeting aurora2 kinase in oncogenesis: a structural bioinformatics approach to target validation and rational drug design. Mol Cancer Ther 2003 2(3):28394.

9. T. Chijiwa, A. Mishima, M. Hagiwara, M. Sano, K. Hayashi, T. Inoue, K. Naito, T. Toshioka, H. Hidaka. Inhibition of forskolininduced neurite outgrowth and protein phosphorylation by a new
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