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SeeSNP Propietary Analysis Advantages

tools (7) have shown promise addressing this challenge and we are currently investigating these tools to offer our customers in the future.

References
1) DA Nickerson, VO Tobe, and SL Taylor. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing, Nucleic Acids Research, July 1997; 25: 27452751.

2) B Ewing, L Hillier, M Wendl, and P Green. Base-calling of automated sequencer traces using phred. I. Accuracy assessment, Genome Research, Mar 1998; 8: 175185.

3) B Ewing and P Green. Base-calling of automated sequencer traces using phred. II. Error probabilities, Genome Research, Mar 1998; 8: 186194.

4) S Weckx, J Del-Favero, R Rademakers, L Claes, M Cruts, P De Jonghe, C Van Broeckhoven, and P De Rijk. novoSNP, a novel computational tool for sequence variation discovery, Genome Research, Mar 2005; 15: 436442.

5) C Korch and H Drabkin. Improved DNA sequencing accuracy and detection of heterozygous alleles using manganese citrate and different fluorescent dye terminators, Genome Research, Jun 1999; 9: 588595.

6) AB Kotlyar, N Borovok, T Molotsky, L Fadeev, and M Gozin. In vitro synthesis of uniform poly(dG)poly(dC) by Klenow exo-fragment of polymerase I, Nucleic Acids Research, Jan 2005; 33: 525535.

7) JK Bonfield, C Rada, and R Staden. Automated detection of point mutations using fluorescent sequence trace subtraction, Nucleic Acids Research, Jul 1998; 26: 3404 3409.


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