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RNA Interference and Gene Silencing: History and Overview

of the siRNA Effect. TechNotes 9(1): 3-5. (Article)

  • Brummelkamp TR, Bernards R, and Agami R. (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553.

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  • Miyagishi M, and Taira K. (2002). U6-promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells. Nature Biotechnol. 20:497-500.

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