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RNA Interference and Gene Silencing: History and Overview

i. USA 99(3):1443-1448.

  • Elbashir SM, Lendeckel W, and Tuschl T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev 15(2):188-200.

  • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, and Tuschl T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498. (Abstract)

  • Caplen NJ, Parrish S, Imani F, Fire A, and Morgan RA. (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrates and vertebrate systems. Proc. Natl. Acad. Sci. USA 98: 9746-9747.

  • Holen T, Amarzguioui M, Wiiger M, Babaie E, and Prydz H. (2002) Positional effects of short interferning RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Research 30(8):1757-1766.

  • Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. (2001) Functional anatomy of siRNA for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 20: 6877-6888.

  • Jarvis RA, and Ford LP. (2001) The siRNA Target Site Is an Important Parameter for Inducing RNAi in Human Cells. TechNotes 8(5): 3-5. (Article)

  • Brown D, Jarvis R, Pallotta V, Byrom M, and Ford L. (2002) RNA Interference in Mammalian Cell Culture: Design, Execution and Analysis
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