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RNA Interference and Gene Silencing: History and Overview

T, Pollien JM, and Vaucheret H. (1998) Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J 16: 4738-4745. (Article)

  • Guo S, and Kempheus KJ. (1995). Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81: 611-620. (Abstract)

  • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, and Mello CC. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811. (Article)

  • Timmons, L., and Fire, A. (1998) Specific interference by ingested dsRNA. Nature 395: 854.

  • Timmons L, Court D, and Fire A. (2001) Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263:103-112. (Abstract)

  • Hunter CP. (2000) Shrinking the Black Box of RNAi. Current Biology 10: R137-R140. (Article)


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