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Quantification of Nucleosomes in Serum,,,by the Cell Death Detection ELISAplus

the acidic DNase II [18]. Summarizing our studies, we recommend the preanalytic handling of the blood samples as indicated in Table 1.



Our first findings seem to indicate that the quantification of the concentration of nucleosomes in serum is a sensitive and fast method useful for monitoring the efficacy of antitumor therapy and estimating the individual sensitivity to therapy. Further studies with more samples, defined tumors and therapeutic regimens will have to prove its significance in clinical practice.




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