als of 1 ml each.
β-Glucuronidase from E. coli K12
New improved quality!
Roche Applied Science recently introduced an improved
β-Glucuronidase (GRD) formulation which replaces the
previous product. The new quality exhibits higher purity
and specific activity compared with products previously
on the market (Figure).
GRD hydrolyses β-glucuronic acid (β-GlcA) esters
(β-glucuronosides) of a variety of compounds, including
steroids, aryl alcohols, drugs, and metabolites. GRD also
hydrolyses polysaccharides that contain β-GlcA linked to
other sugars. GRD is highly specific for the carbohydrate
portion of the molecule but has very little specificity for
the molecule conjugated to β-GlcA. The main research
- Analysis of steroid conjugates
- Doping analysis (horses)
- Drug and alcohol testing
- Tests in pathology labs
The performance in steroid analysis and doping analysis
was demonstrated by Ute Mareck, German Sport
University, Cologne, Germany, and Thierry Rousseau, National Doping Testing Laboratory (LNDD), Chtenay-