Navigation Links
Proteomics in Bladder Cancer Research: Protein Profiling of Bladder Squamous Cell Carcinomas, Rev C

disease may exhibit expression profiles and immunofluorescent staining patterns that closely resemble those observed in the invasive tumors. These lesions, if detected, may provide important clues about protein expression profiles and immunofluorescence patterns that may be associated with bad prognosis.

To illustrate the approach, Figure 4 shows immunofluorescent staining of cryostat sections of an SCC tumor (Figures 4B, E, H, K, and N) and urothelium with field disease (Figures 4C, F, I, L, and O) obtained from a patient with invasive disease. As depicted in the figure, the tumor does not stain with keratin 19 antibodies (Figure 4B), is BG3C8-antigen positive (Figure 4E) (Celis et al. 1996b), keratin 13 negative (Figure 4H), keratin 14 positive (Figure 4K), and psoriasin negative, with the exception of the pearls (Figure 4N). Similar analysis of the urothelium with field disease revealed a small area (indicated with large arrows) that stained weakly with the keratin 19 antibody (Figure 4C, indicated with an arrow) and that is BG3C8-antigen positive (Figure 4F), keratin 13 negative (Figure 4I), keratin 14 positive (Figure 4L), and psoriasin negative (Figure 4O). Other regions of the urothelium, one of which is indicated with small arrows, showed immunofluorescence patterns that were clearly different from those observed in the invasive tumor. We believe that a thorough analysis of the different antigen expression patterns detected in tumors and urothelium with field disease may prove instrumental in identifying those that may progress to invasive disease. As reference, we show in Figures 4A, D, G, J, and M immunofluorescence pictures of cryostat sections from normal urothelium obtained from another patie
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11

Related biology technology :

1. Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
2. Cancer siRNA Oligo Set Version 1.0
3. Cancer-Related miRNAs Uncovered by the mirVana miRNA Microarray Platform
4. Detection of Mutant K-ras in a Kindred With Hereditary Pancreatic Cancer by DGGE
5. Detection of p53 Gene in Breast Cancer by Denaturing Gradient Gel Electrophoresis and the DCode System
6. Genome Wide Profiling of Paired Cancerous and Normal Breast Tissues and Rapid Interpretation of Gene Expression Data
7. A New C-Terminal GST Vector for Protein Production in S. pombe
8. New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
9. Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
10. Simple, Sensitive, and Rapid Detection of FLAG -Tagged Fusion Proteins
11. New Yeast Cloning System for Producing Proteins with Native Amino Acid Sequences
Post Your Comments:
(Date:12/24/2014)... PharmaBoardroom,s new report, , ... available for free download , digs deep into this ... in the sector today. One area where ... in developing a homegrown pharmaceutical manufacturing base, even if the ... some way off. A cursory comparison with neighboring ...
(Date:12/22/2014)... Md. , Dec. 22, 2014 /PRNewswire/ ... SYN), a developer of pathogen-specific therapies for ... on protecting the microbiome, today announced positive ... Phase 1a clinical trial of SYN-004, the ... prevention of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... The American Journal of Hematology/Oncology, ... and editorials addressing developments and pathways related to ... provocative article exploring the role of follicle-stimulating hormone ... of prostate cancer. , The article references ... that there could be a connection to prostate ...
(Date:12/19/2014)... 2014 BioPlus Specialty Pharmacy ... the promotion of Nick Maroulis, Pharm.D. to the newly ... , In this position, Dr. Maroulis will continue ... the directors of our multi-site pharmacies as the company ... and during that time he has served in many ...
Breaking Biology Technology:PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2
... ... Ingredients for Follow-on Biologics in Chicago. , ... Chicago (Vocus) April 22, 2010 -- Therapeutic Proteins Inc. ... (or biosimilars) manufacturing facility constructed to meet U.S. Food and Drug Administration (FDA) requirements. ...
... iCardiac ... , ... (PRWEB) April 22, 2010 -- iCardiac Technologies, Inc., a provider of next generation cardiac ... a cardiac safety study leveraging iCardiac’s COMPAS technology platform including advanced ECG biomarker analyses., ...
... Promega Corporation now ... whole blood. , ... 21, 2010 -- Promega Corporation now offers the Maxwell® 16 LEV Blood DNA Kit ... work on the Maxwell® 16 instrument, eliminates the need for a buffy coat step while ...
Cached Biology Technology:Therapeutic Proteins Inc. Completes First Independent, Dedicated Biosimilars Manufacturing Facility in U.S. 2Therapeutic Proteins Inc. Completes First Independent, Dedicated Biosimilars Manufacturing Facility in U.S. 3Therapeutic Proteins Inc. Completes First Independent, Dedicated Biosimilars Manufacturing Facility in U.S. 4Another Top 10 Pharmaceutical Company Awards Cardiac Safety Study to iCardiac 2New Promega Maxwell 16 LEV Blood DNA Kit Surpasses Concentration Standards in Less Time 2
(Date:12/17/2014)... Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ... "Samsung Galaxy S5 - Home Button Synaptics Fingerprint ... http://photos.prnewswire.com/prnh/20130307/600769 ... than the iPhone 5S, Samsung introduces for the ... The Galaxy S5 home button presents ...
(Date:12/17/2014)... 16, 2014 Research and Markets ... the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major trend ... for medical sensors in biomedical applications. Chemical sensors ... and correct diagnosis during surgical procedures. The Global ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has ... in India 2015-2019" report to their offering. ... this market is the adoption of multimodal biometric ... characteristic of an individual for verification and identification ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... climate changes over the past several decades have led ... squirrels, birds and mosquitoes, according to University of Oregon ... the June 9 issue of SCIENCE, William E. Bradshaw, ... show that diverse animal populations have changed genetically in ...
... University of Florida scientists conducting experiments with mice have ... of cells in the eye essential for healthy vision. ... cell layer vital for eyesight called the retinal pigment ... writing in a recent issue of Investigative Ophthalmology & ...
... of human autoimmune disorders and other diseases works by dialing ... production, University of Michigan researchers have found. , "Many drugs ... Gary Glick, who is the Werner E. Bachmann Collegiate Professor ... volume control, so we're able to dial enzyme activity down ...
Cached Biology News:Recent, rapid climate change is driving evolution of animal species 2Bone marrow may restore cells lost in vision diseases 2Bone marrow may restore cells lost in vision diseases 3Drug dials down the energy within cells, UM researchers find 2
Cell Culture Flask, 175 cm, tissue-culture treated polystyrene, barcoded...
... Stabilizer is an aqueous solution that contains ... chemicals in a PBS buffer (phosphate buffered ... product contains a combination of 0.02% methylisothiazolone ... StabilCoat Plus Stabilizer provides optimum performance for ...
... Anti-PSD-95, clone K28/86.2, PDZ Domain ... Immunogen : GST fusion to residues ... 0.01M Tris pH 7.4, 0.075M NaCl ... routinely evaluated by immunoblot on rat ...
... Immunodepletion Kit specifically removes 20 of the ... serum in preparation for further proteomics analysis. ... plasma proteome whether you use one- or ... go straight to mass spectrometry. This is ...
Biology Products: