Prominence UFLC has been designed to achieve Ultra-Fast HPLC by utilizing the Prominence hardware series. In this respect, we are successful in demonstrating high speed and separation performance without resorting to high pressure, while providing high reliability and expandability not available with other fast LC systems.
Smaller particle columns such as sub-2m columns generate higher pressures but also produce high separation efficiency. Sub-2m columns often require specialized instruments that can operate under high pressure to demonstrate high separation efficiency. Our Shim-pack XR-ODS column was developed with the intention of creating a new high-speed analysis column at much lower pressure than experienced with sub-2m columns. The Prominence UFLC has been optimized to enable highspeed analysis using the Shim-pack XR-ODS.
Shim-pack XR-ODS for High Speed and High Separation Efficiency
The Shim-pack XR-ODS, which is packed for use in reverse-phase chromatography, has 2.2m diameter particles of totally porous high-purity silica gel with chemically bonded octadecylsilane (ODS) as the base material. Generally, columns using smaller particles provide good separation when using shorter length columns and help to minimize the reduction in column efficiency even if the mobile phase flow rate is high. This makes them well suited to high-speed analysis. However, since column pressure increases inversely proportional to the square of the diameter of the packing material particle, special HPLC instruments that have resistance to high pressure are required.
The specialized instruments that allow use of sub-
2m columns often sacrifice operability, reliability and
application flexibility. The design of the