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Preserve Samples for RNA Expression Microarrays RNAlater Around the World


RNAlater protects cellular RNA within specimens during sample collection and during shipping. Whether you are in the lab, in the OR, or out in the field, you can use this aqueous, non-toxic Tissue Collection:RNA Stabilization Solution from ambient temperatures down to -20C.

Characterization of disease mechanisms using high throughput technologies often involves collaborations with a core facility for processing samples and data. Tissue procurement is a critical first step in the path to quantifying gene expression. Standardization of this step enables more accurate expression profile comparisons--both within a study and across published reports. The two studies described below demonstrate how RNAlater can protect RNA expression profiles within samples destined for array analyses without requiring specialized equipment (e.g. liquid nitrogen and associated containers) or handling (e.g. RNAlater is non-toxic and samples are stable at ambient temperatures).


Microarrays with Human Uterine Tissue

To expedite transfer of discoveries in genomic medicine to clinical care, Dr. George Mutter and colleagues conducted a comprehensive study to assess the impact of tissue sample source, tissue processing protocol, and random noise on microarray analyses [1]. Single uterine myometrium biopsies from randomly selected
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