( for delivery of valuable reagents such...)New Tools for Making and Processing Protein Microarrays.

A ProteinArray Workstation is comprised of:

(1) a Reagent Delivery System and

(2) up to 4 ProteinArray Processors.

The Reagent Delivery System supplies the 6 bulk buffers to the ProteinArray Processor, or Processors, as well as pressure and vacuum lines that control the system. All of the reagent reservoirs are contained within an enclosure enabling safe storage of buffers and reducing dust contamination.

The ProteinArray Processors can be stacked to minimize the system footprint and save laboratory bench space. Each ProteinArray Processor can be operated independently and can process up to 12 protein microarrays in parallel. As each successive ProteinArray Processor is incorporated the total protein microarray capacity of the entire system increases from 12 to 24, to 36 or to 48 microarrays, with each Processor remaining independently controllable.

Once one Processor has been installed, the system can be easily upgraded by adding further Processors, as the researchers needs increase. This enables the system to be used by a small or large research laboratory, by single or multi-users, or even in a core facility where high throughput capability in a multi-user environment is required. Since the Processors are independently controlled, different assay methods can be processed concurrently on each Processor, enabling high throughput, flexible operation and fast method development.

Core to the ProteinArray Processor is the unique design of the microfluidics and sample injection system. Each ProteinArray Processing Cell is comprised of a stack of components with micro channels and valves that are firmly clamped into position and are not normally disassembled by the operator
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