Navigation Links
Near Infrared Technology and Optical Agents For Molecular Imaging

luorescent proteins. In addition, NIR optical imaging has a further advantage in that it has the potential to translate into the clinic. Several NIR imaging ins-truments for use on humans are currently under development. De Grand and Frangioni have described a prototype NIR optical imaging system for use with NIR fluoro c h rome-labeled optical agents in non-inva s i ve intraoperative imaging procedures12. The authors envision the system being eventually used for imageguided cancer resection with real-time assessment of surgical margins, sentinel lymph node mapping, and intraoperative mapping of normal and tumor vasculature. Furthermore, Gurfinkel et al. , Hawrysz and Sevick-Muraca, and Chen et al. , have described NIRbased imaging instruments directed at the early detection of breast cancer3, 13, 14. These instruments potentially could be used for guiding fine needle biopsies and sentinel lymph node monitoring during surgery.

There are several biological barriers that should be taken into consideration when using NIR dye - labeled optical probes. The probe must be able to reach its target in sufficient concentration and with sufficient binding affinity that it can be imaged. In this respect, optical probes are similar to a pharmaceutical agent in that considerations of absorption, distribution, metabolism, exc retion, and tox i c i t y need to be evaluated. In addition to non-specific binding, trapping, rapid excretion, and metabolic effects, there are delivery barriers to be overcome. For example, the size and characteristics of the dye labeled ligand may prevent it from crossing the blood-brain barrier. However, the combination of an NIR labeling agent such as IRDye 800CW and NIRbased imaging instruments used for both small animal and clinical imaging has the potential to provide both good spatial resolution and sensitive detection of targeted molecule
'"/>

Source:


Page: All 1 2 3 4 5 6 7

Related biology technology :

1. Innovative Tissue Array Technology for High-Throughput Screening of Gene Expression
2. Enhancing Ruggedness and Full-Scan MS Sensitivity Using Ion Sweep Technology
3. Novel MicroRNA Array Technology for Sensitive miRNA Profiling
4. Use of FlashPlate Technology for In Vitro Measurement of [35S]-GTPγS Binding in CHO Cells Expressing the Human 5-HT1B Receptor
5. Use of Novel FlashPlate Technology to Measure cAMP Accumulation in Chinese Hamster Ovary Cells Expressing Human -2 Adrenoreceptors
6. Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor
7. DNA purification from pig ears to bird blood using proven DNeasy Technology
8. Eagle Eye Optical Filter Optimized for Imaging Silver-Stained Gels
9. Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
10. Genotyping Single Nucleotide Polymorphisms with Molecular Beacons
11. New Protocols for Isolating High- Molecular-Weight Genomic DNA
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Near Infrared Technology and Optical Agents For Molecular Imaging

(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Biotech Inc. (TSX:,ONC, NASDAQ: ONCY) announced today ... a poster presentation entitled "In Vivo Efficacy ... in,Nude Mice Bearing Human Melanoma Xenografts" at ... Cancer Therapeutics. SAIC-Frederick is,the prime contractor to ...
... Biosystems,Inc. (OTC Bulletin Board: WGBS), a leading developer ... cell research systems,today announced that Alnoor Shivji, WaferGen,s ... presentation at the Seventh,Annual BIO Investor Forum. The ... Palace Hotel in San Francisco, WaferGen,s presentation ...
... Soliris(R) in U.S. and Europe, Reported Net Sales ... Quarter Shipments, Company Revises Revenue Guidance Upward and ... 2008, Pipeline Progress in Hematology, Oncology, Transplant, Neurology, ... (eculizumab) net product sales of $76.5 million in Q3,2008 ...
Cached Biology Technology:Oncolytics Biotech Inc. Collaborators Present Reovirus and Melanoma Research at EORTC-NCI-AACR Symposium 2Oncolytics Biotech Inc. Collaborators Present Reovirus and Melanoma Research at EORTC-NCI-AACR Symposium 3WaferGen to Present at the Seventh Annual BIO Investor Forum 2Alexion Reports Third Quarter 2008 Results 2Alexion Reports Third Quarter 2008 Results 3Alexion Reports Third Quarter 2008 Results 4Alexion Reports Third Quarter 2008 Results 5Alexion Reports Third Quarter 2008 Results 6Alexion Reports Third Quarter 2008 Results 7Alexion Reports Third Quarter 2008 Results 8Alexion Reports Third Quarter 2008 Results 9Alexion Reports Third Quarter 2008 Results 10Alexion Reports Third Quarter 2008 Results 11Alexion Reports Third Quarter 2008 Results 12Alexion Reports Third Quarter 2008 Results 13Alexion Reports Third Quarter 2008 Results 14
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a ... announced that its DigitalPersona ® Pro Enterprise ... have been deployed throughout First Bank branch locations ... South Carolina and Virginia. First Bank, ... Southern Pines, North Carolina , selected ...
(Date:11/21/2014)... November 18, 2014 According to ... by Systems (Video, RFID, Access Control, Intrusion Detection, Parking ... Banks, Government), Component Service Geography - Global Forecasts to ... is projected to be around $25 Billion in 2014 ... growing at a CAGR of 8.69%. Browse ...
(Date:11/21/2014)... REDMOND, Wash. , Nov. 20, 2014 ... access for the Internet of Things (IoT), today announced ... position of chief operating officer. Previously a strategic advisor ... marketing, finance, and operations. Mr. Traynor is based out ... . He reports to Chris Muench , ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... HERNDON, Va., Aug. 5, 2011 GTSI Corp. (NASDAQ: ... integrator for federal, state and local governments, announced today ... by the U.S. Army.  This contract will provide war ... of persons of interest in the field. The contract ...
... PARK, Md. -- New computer modeling work shows that by ... atmosphere to less than 40 percent higher than it is ... means of reducing emissions. This includes more nuclear and renewable ... that capture and store carbon dioxide, and even using forests ...
... dinosaurs that lived near the South Pole, sometimes in the ... similar to dinosaurs that lived everywhere on the planet, according ... surprising fact falsifies a 13-year-old study and may help explain ... million years, said Holly Woodward, MSU graduate student in the ...
Cached Biology News:GTSI Wins Department of Defense Contract to Provide Biometric Automated Toolset Systems for U.S. Army 2Human influence on the 21st century climate: 1 possible future for the atmosphere 2Human influence on the 21st century climate: 1 possible future for the atmosphere 3Human influence on the 21st century climate: 1 possible future for the atmosphere 4New Montana State research sheds light on South Pole dinosaurs 2New Montana State research sheds light on South Pole dinosaurs 3
KNP-1 (HES1) Purified Anti-Mouse, Anti-Rat, Anti-Human, Anti-Dog, Anti-Chicken clone 35, Isotype Mouse IgG 1 , 150 µg Consult technical datasheet for details....
NATIVE RAT OSTEOCALCIN...
Form: Ready to use Applications: ELISA...
Goat polyclonal to p27 KIP 1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-KRPATDDS STQNK, corresponding to Internal sequence amino acids 153-165 of Human p27 KIP 1 ...
Biology Products: