Navigation Links
Near Infrared Technology and Optical Agents For Molecular Imaging

ion with the subsequent generation of light upon contact with luciferin. This approach requires the creation of modified cells, and analysis is limited to cells expressing the luciferase gene. Thus it is not translatable to clinical practice.

In a second approach, cells engineered to express fluorescent proteins can be used to mark tumors. The recombinant tumor cells can be implanted into animals and, following excitation with an appropriate light source, the fluorescence from the expressed fluorescent proteins can be detected by means of a CCD camera. The excitation and emission wavelengths of commercially available fluorescent proteins are generally in the visible region of the spectrum. As discussed in this publication, this region can be compromised by tissue autofluorescence and nonspecific background. Also, this method requires transgenic cell lines and is thus limited in its ability to detect a variety of potential targets. Similar to bioluminescent imaging, this method cannot translate to the clinic.

A more flexible and direct approach employs targeted imaging agents consisting of antibodies, receptor binding ligands, small molecules, or peptides labeled with fluorochromes. The fluorescent labels can be visualized by excitation with an appropriate light source and the emitted photons captured via a CCD camera or other optical detector.

For fluorescent imaging, there are generally three parameters which are used to characterize the interaction of photons with tissues. The three processes are light absorption, light scattering, and fluorescent emission. A fundamental consideration in optical imaging is maximizing the depth of tissue penetration. Absorption and scattering of light is largely a function of the wavelength of the excitation source1. In general, light absorption and scattering decreases with increasing wavelength2. Be
'"/>

Source:


Page: All 1 2 3 4 5 6 7

Related biology technology :

1. Innovative Tissue Array Technology for High-Throughput Screening of Gene Expression
2. Enhancing Ruggedness and Full-Scan MS Sensitivity Using Ion Sweep Technology
3. Novel MicroRNA Array Technology for Sensitive miRNA Profiling
4. Use of FlashPlate Technology for In Vitro Measurement of [35S]-GTPγS Binding in CHO Cells Expressing the Human 5-HT1B Receptor
5. Use of Novel FlashPlate Technology to Measure cAMP Accumulation in Chinese Hamster Ovary Cells Expressing Human -2 Adrenoreceptors
6. Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor
7. DNA purification from pig ears to bird blood using proven DNeasy Technology
8. Eagle Eye Optical Filter Optimized for Imaging Silver-Stained Gels
9. Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
10. Genotyping Single Nucleotide Polymorphisms with Molecular Beacons
11. New Protocols for Isolating High- Molecular-Weight Genomic DNA
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Near Infrared Technology and Optical Agents For Molecular Imaging

(Date:9/2/2015)... ... ... Temarry Recycling's new $100,000 waste to energy capital project ... to contribute to the sustainability of our natural resources. , Waste to Energy ... operating at their Mexico facility, Recicladora Temarry, for the last 7 years. While ...
(Date:9/1/2015)... , ... September 02, 2015 , ... Spirax Sarco ... features to its eCommerce site Spirax Sarco Anytime. This platform, offering unique online ... to place your next order? Log on to Spirax Sarco Anytime and within ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... of the new ImageXpress® Micro Confocal High-Content Imaging System. This transformative system ... that use 3D cellular models such as spheroids, tissues, and organisms. ...
(Date:9/1/2015)... Sept. 1, 2015 The Dohmen Company ... , Ph.D., MBA as Chief Science Officer (CSO) ... newly created role, Dr. Floyd will lead Dohmen,s ... portfolio of pre-commercial and post approval outsourced services ... medical communications.  Dr. Floyd brings decades of experience ...
Breaking Biology Technology:Temarry Recycling’s New $100,000 Waste to Energy Renovation 2Spirax Sarco Announces New Features to Anytime Platform 2ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 2ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 3Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 2Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 3
... Council , a policy advisor to the governor and ... additions to its board of directors. , ,The new ... that includes more than three dozen members of the ... leaders: , , Eric Apfelbach, president and CEO of ...
... of the 35 Midwestern venture capital deals reported during ... isn\'t alarmed. , ,A MoneyTree Report released ... of $185 million during the quarter, compared to three ... state\'s historic difficulty with attracting venture capital, some view ...
... which provides software and services to the financial and ... up 13 percent to $1.1 billion. , ,Net income ... the company made in the first quarter of 2005 ... the first quarter included repurchasing 5.4 million shares of ...
Cached Biology Technology:Angel investing should lead to more venture funding, Ward says 2Angel investing should lead to more venture funding, Ward says 3
(Date:9/2/2015)... 2015 Security of data and assets ... government organizations, telecommunications, hospitals, as well as individuals. ... being used to prevent unauthorised access. Technological advancements ... individuals could gain access to secure premises after ... hardware devices and numeric codes. However, hackers also ...
(Date:8/28/2015)... According to a new market ... Type (Pen & Paper Based, Hosted, Biometrics), Service, Application ... Research), Vertical and Region - Global Forecast to 2020", ... grow from USD 2.4 Billion in 2015 to USD ... Rate (CAGR) of 25.6% from 2015 to 2020. ...
(Date:8/20/2015)... 2015 The wearable technology market has ... and healthy. However, wearable technology has the potential ... help improve diagnostic capabilities and therapeutic outcomes. Today, ... Wearable Technologies Conference 2015 , where Barrett ... in healthcare.    "Over the past ...
Breaking Biology News(10 mins):Global Biometrics Spending Market in the Government Sector 2015-2019 2Global Biometrics Spending Market in the Government Sector 2015-2019 3Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 2Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 3Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 4Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3
... Madison WI November 17 2010 There is ... animal hormones have on surface water. Higher concentrations of ... and sexual impairment in fish and other aquatic species. ... examined estrogen concentrations runoff from agricultural fields fertilized with ...
... The most widely adopted measure for assessing the state ... in nearly half the ecosystems where it was applied. ... fisheries scientists, and is reported in this week,s issue of ... it,s like flipping a coin; half the time you get ...
... Annual Meeting 2011 will feature the latest findings ... research. This year,s Annual Meeting focuses on innovative ... clinical trials and new approaches to cancer prevention. ... the Annual Meeting, the program schedule and related ...
Cached Biology News:Pelletized manure reduces toxic runoff 2Widely adopted indicator of fisheries health questioned 2Widely adopted indicator of fisheries health questioned 3Widely adopted indicator of fisheries health questioned 4
One-step, microplate or cuvet, colorimetric, linear detection range 0.6 mM to 100 mM. Procedure: 2 min....
[5,6,8,9,12,14,15(n)-3H]Prostaglandin D2, 925 kBq, 25 uCi. Methanol:water:acetonitrile (3:2:1) solution.> 3.0 TBq/mmol, > 80 Ci/mmol.3.7 MBq/ml, 100 uCi/ml. Category: Radiochemicals &Radiation Safety...
EnzChek cellulase substrate *blue fluorescent, 339/452...
Request Info...
Biology Products: