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Madison-based Mithridion seeks to capitalize on Alzheimer's breakthrough

Springing out of a promising research breakthrough on Alzheimer's disease, UW-Madison researcher Jeff Johnson has co-founded Mithridion Inc. in hopes of commercializing an Alzheimer's-inhibiting drug.

Johnson and fellow researcher Thor Stein led a team that began about four years ago by asking a simple question: Why don't mouse neurons die when slammed by a protein thats been shown to kil......

Full article >>> ember through Biopons, a professional services company for which he also serves as CEO. Biopons specializes in creating and developing homegrown biotech companies and also is working on relocating a couple of overseas companies here in Wisconsin.

Johnson sat down with Biopons in October to discuss the science behind the company and concocted a proposal for forming Mithridion. The company ......

Full article >>> ng in the brains of Alzheimer's victims. But if that same parent protein is cut by a different enzyme, it generates another protein that counteracts the toxicity of the first.

"So it turns out that this 'good cut' protein from the big parent protein was actually causing this significant induction of these protective mechanism that blocked the bad protein toxicity. That was very interesti......

Full article >>> drug that stops the disease."

Lincoln Brunner is a WTN contributing editor and can be reached at

Full article >>>
'"/> By Lincoln Brunner 03/23/05

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