Navigation Links
Is Z' factor the best assessment for the quality of cellular assays delivering higher content?


High information-content image-based cellular assays have properties distinct from more traditional screening assays, and their evaluation may therefore require adoption of additional statistical metrics.

S:N calculations that take into account standard deviation of both positive and negative controls are less prone to error than those derived from the standard deviation of negative controls only.

Both S:N and Z factor may provide valuable information during assay and image analysis optimization.

The theoretical relationship between Z factor and S:N (method B) has been shown to be well supported by the results of several cell-based assays performed using IN Cell Analyzer 3000 and IN Cell Analyzer 1000.


back to top
'"/>

Source:


Page: All 1 2 3 4

Related biology technology :

1. Critical factors for successful microarray and real-time PCR analyses
2. Using the Agilent 2100 bioanalyzer for quality control of protein samples prior to MS-analysis
3. Advancing the quality control methodology to assess isolated total RNA and generated fragmented cRNA
4. Evaluation of RNA isolated from human tissues: quality control for surgical and postmortem samples
5. Enzyme Immunoassay for Studying Intracellular Levels of cAMP
6. Cis-Reporting System Monitors Intracellular Calcium Mobilization
7. Cis-Reporting System Monitors Intracellular Calcium Mobilization
8. Mycobacterium intracellulare
9. Mycobacterium intracellulare
10. Detection of antibody-stained cell surface and intracellular protein targets with the Agilent 2100 bioanalyzer
11. Measuring Intracellular Enhanced Green Fluorescent Protein With the VersaFluor Fluorometer

Post Your Comments:
(Date:11/9/2009)...a research industry first, allowing veterinary res...afety study data to be managed in one software app... NJ (PRWEB) November 9, 2009 -- Xybion Medical Sys...™ VM, an integrated enterprise software solu...d care of veterinary research subjects. Pristima&t...
(Date:11/8/2009)... Complete Genomics, a third-generation human genom...of a report in the journal Science describing it...nalysis of sequence data from three complete human...omes sequenced on the proof-of-principle genomic D...to $1,726 for 45x coverage for the samples describ...
(Date:11/6/2009)...tCall/ -- BioSpecifics Technologies Corp. (Nasdaq:...irst-in-class collagenase-based products, today an...r ended September 30, 2009. ,, "We were extrem...,s Arthritis Advisory Committee unanimously recomm...TM) for the treatment of Dupuytren,s disease, and ...
(Date:11/6/2009)...wire/ -- EUCODIS Bioscience, a company,developing,... for the,chemical industry announced today that it...dus, the leading biopharmaceutical company in Lati...Bioscience exclusive access - for the search,of en...ection of,psychrophilic bacteria strains and other...
Breaking Biology Technology:Xybion Unveils Pristima™ VM, an Integrated Enterprise Software Solution for Vivarium and Veterinary Care Management 2Complete Genomics publishes in Science on low-cost sequencing of 3 human genomes 2Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 2Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 3Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 4Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 5Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results 6EUCODIS Bioscience to Explore Novel Enzymatic Activities in Antarctic Bacteria Library From Bio Sidus 2
...in Shipping Dronabinol Soft Gel Capsules Immediate...ical Companies, Inc. (NYSE: PRX ) today announced... Food and Drug Administration for its,Abbreviated ...sion of,Solvay Pharmaceutical,s Marinol(R), a CIII... treat nausea and vomiting associated with cancer,...
...alif., June 30 As most doctors face the,Congressi...s next week,Arcadian Health Plan, Inc. announced t...network physicians at the same level of payment as...o supporting its physician,partners as they contin...,members., Arcadian recognizes the value and qual...
...H, Mass. June 30 Joseph B. Bolen, Ph.D., CSO,of M... Cancer track IBC,Life Sciences Drug Discovery & D...nd Exhibition taking place August 4-7 at the World.... The cancer track presentations will,focus on the...ncers, and,Clinical Biomarkers., Bolen has confir...
Other Biology Technology:Par Pharmaceutical Receives Final Approval to Market Generic Marinol(R) CIII (Dronabinol) Capsules 2Par Pharmaceutical Receives Final Approval to Market Generic Marinol(R) CIII (Dronabinol) Capsules 3Joseph B. Bolen, Ph.D. from Millennium to Conference Chair Cancer Sessions at IBC's Drug Discovery & Development of Innovative Therapeutics Conference 2
(Date:11/5/2009)... , The National Association of Biology Teachers (...or of biological sciences at Naugatuck Valley Comm...th the 2009 Evolution Education Award during the N...be held 11-14 November 2009 in Denver, Colorado. ,... the American Institute of Biological Sciences,(A...
(Date:11/4/2009)... , Heavy traffic corridors in the cities of Long ...ant proportion of preventable childhood asthma, an...ons on the disease has likely been underestimated,...thern California (USC). , The study, which appe...of Public Health , estimated that nine percent of ...
(Date:11/4/2009)... , PORTOLA VALLEY, Calif., Oct. 19 /PRNewswir...nced molecular sensing and imaging devices which s...today that it has signed exclusive distribution de...and Sensors. The markets covered include Australi...urg (Benelux), Suriname, Italy, France, Spain, Por...
Breaking Biology News(10 mins):Biologists, educators recognize excellence in evolution education 2USC study finds big air pollution impacts on local communities 2Spectros Signs New International Distribution Deals 2Illinois Medical District Recognizes Officers of its District Security Group 47860 1Illinois Medical District Recognizes Officers of its District Security Group 47860 2Pharmaxis Announces Placement of 2447 Million and Share Purchase Plan 12459 1Pharmaxis Announces Placement of 2447 Million and Share Purchase Plan 12459 2Orlando Dermatology Aesthetic 26 Clinical 28ODAC 29 Conference Announces Its 2010 Event 47854 1Orlando Dermatology Aesthetic 26 Clinical 28ODAC 29 Conference Announces Its 2010 Event 47854 2
...ered that two microRNA (miRNA) molecules help cont...of B-cell chronic lymphocytic leukemia (B-CLL), th...r findings, published in the December 15 issue of ...ing as powerful regulators of gene expression in c... drug treatment, the investigators say. , In t...
...blem could be eliminated simply by dusting slag on...& Industry, the magazine of the SCI. , In the ...f damage annually. , Researcher David Cowen and...t applying slag to wheat growing in greenhouses ha...orporate the silica and express it as spiky struct...
... of plants to defend themselves by accumulating hi...me insects, and that such adaptation potentially e...ites may in turn evolve to deal with high levels o...zabeth Pilon-Smits of Colorado State University an...rnia, Berkeley, appear in the November 21st issue ...
Other Biology News:Pair of microRNA molecules controls major oncogene in most common leukemia 2New moth variety disarms plants guarded by selenium 2
...ystem - dUTP with CyScribe GFX Purification Kit, 5...f Cy3- and Cy5-labeled cDNA.Optimized reagents are...purification.Flexible and optimized protocols can ...her Cy3- or Cy5-labeled nucleotides.Reliable purif...
Canine serum from Equitech-Bio
Rabbit Anti-TOLLIP Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
... mA, 100 W maximum.Constant voltage, constant curr...ts in settings and read-outs for precision and rep...tstanding choice for non-IEF ultrathin flatbed gel...Electrophoresis Systems & Standards & Reagents, Po...
Biology Products: