Other automated methods of cell counting currently in use have not solved the critical points of reproducibility and rapidity to satisfaction. To date, automated viability determinations have been based on either the Trypan blue exclusion method or on differentiation between cells sizes using impedance. Many of these systems require frequent calibration for cell size or morphology prior to use; often, these requirements compromise the accuracy of the final result. As indicated in the example above, the NucleoCounter delivers reproducible precision and is a low-maintenance unit that does not require calibration for cell type or morphology.
Mr. Ioannides is an employee of New Brunswick Scientific Co., Inc., Box 4005, 44 Talmadge Rd., Edison, NJ, 08818-4005, U.S.A.; tel.: 877-723-3314; fax: 732-287-4222; e-mail: email@example.com; home page: www.nbsc.com/ABL7.htm. NucleoCounter , NucleoCassette, and NucleoView software are registered trademarks of ChemoMetec A/S, Allerd, Denmark, and are distributed exclusively in North America by New Brunswick Scientific Co., Inc.