Navigation Links
FluoroMax multiwavelength capability

Simultaneously monitoring the levels of relevant metabolites and cell parameters is necessary to properly assess the effectiveness of drugs on living cells. The FLUOROMAX spectrofluorometer allows the user to monitor up to eight wavelength-pairs of emission and excitation wavelengths. Coupling this capability with the proper probes can produce a real-time analysis of unfolding biological processes.

One research application that used simultaneous observation of multiple wavelength-pairs was performed by M. Kimura, et al., at the University of Medicine and Dentistry of New Jersey. 1 Their evaluation of Thapsigargin, a hypertensive drug, was performed on a FLUOROMAX spectrofluorometer. The results demonstrated that the effect of the drug in human platelets was not limited to the elevation of the Ca2+ but produced substantial changes in the overall ionic balance.

Figure 1 shows a sample screen display taken from DATAMAX (FLUOROMAX software for Windows). Note how DATAMAX makes the monitoring of up to eight wavelengthpairs a simple matter of selection.

FLUOROMAX, with DATAMAX software, allows the user to monitor wavelengthpairs to characterize processes in living cells and other biological systems. The measurement is feasible in real time because of the FLUOROMAX spectrofluorometers ability to scan rapidly (up to 200 nm s1).

1 Kimura, M.; et al. J. Physiol. 1993, 494, 113.

back to top


Page: All 1

Related biology technology :

1. Photoluminescence Spectroscopy of Quantum Dots, monitored by the Spex FluoroMax
2. Near IR capability of the FluoroLog
Post Your Comments:

(Date:11/24/2015)...  Clintrax Global, Inc., a worldwide provider of clinical research services ... that the company has set a new quarterly earnings record in ... growth posted for Q3 of 2014 to Q3 of 2015.   ... , with the establishment of an Asia-Pacific ... United Kingdom and Mexico , ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... This fall, ... at competitive events in five states to develop and pitch their BIG ideas to ... from each state are competing for votes to win the title of SAP's Teen ...
(Date:11/24/2015)... 24, 2015 SHPG ) announced today that ... Piper Jaffray 27 th Annual Healthcare Conference in ... at 8:30 a.m. EST (1:30 p.m. GMT). --> SHPG ... will participate in the Piper Jaffray 27 th Annual Healthcare ... Tuesday, December 1, 2015, at 8:30 a.m. EST (1:30 p.m. GMT). ...
(Date:11/24/2015)... -- Tikcro Technologies Ltd. (OTCQB: TIKRF) today announced that its Annual General Meeting ... Israel time, at the law offices of ... th Floor, Tel Aviv, Israel . ... Izhak Tamir to the Board of Directors; , election of ... approval of an amendment to certain terms of options granted to our ...
Breaking Biology Technology:
(Date:11/2/2015)... 2015  SRI International has been awarded a contract ... services to the National Cancer Institute (NCI) PREVENT Cancer ... expertise, modern testing and support facilities, and analytical instrumentation ... toxicology studies to evaluate potential cancer prevention drugs. ... Cancer Drug Development Program is an NCI-supported pipeline to ...
(Date:10/29/2015)... JOLLA, Calif. , Oct. 29, 2015  The ... a new report titled, "DNA Synthesis and Biosecurity: Lessons ... well the Department of Health and Human Services guidance ... issued in 2010. --> ... but it also has the potential to pose unique ...
(Date:10/29/2015)... ARBOR, Mich. , Oct. 29, 2015 /PRNewswire/ ... Eurofins Genomics for U.S. distribution of its DNA ... DNA-seq kit and Rubicon,s new ThruPLEX Plasma-seq kit. ... to enable the preparation of NGS libraries for ... plasma for diagnostic and prognostic applications in cancer ...
Breaking Biology News(10 mins):