( ing low or higher siRNA amounts as req...)FlexiPlate siRNA

Easy access
At QIAGENs GeneGlobe Web portal, it is easy to search for siRNAs for genes of interest and to arrange plate layouts to suit screening experiments. Lists of gene names, Entrez Gene IDs, RefSeq IDs, siRNA names, or catalog numbers can be uploaded, making the process of plate ordering fast and easy. Plates can be ordered immediately or saved for later changes or ordering. Plate layouts can also be downloaded for your records (Figure 1).

Easily Create and Order FlexiPlate siRNA

Figure 1 Create plates at www.qiagen.com/GeneGlobe

Cutting-edge siRNA design
New advances in the siRNA design process ensure that QIAGENs highly innovative and sophisticated HP OnGuard siRNA Design delivers potent and specific siRNA. siRNAs are designed using neural-network technology based on an extremely large set of data from RNAi experiments (1). siRNA design is then checked for homology to all other sequences of the genome using an up-to-date, nonredundant sequence database and a proprietary homology analysis tool which incorporates exciting new features (Figure 2).

New design features:
siRNA target sequence from up-to-date NCBI databases
siRNAs are designed against the most up-to-date gene sequences from the NCBI. Using the latest sequence information ensures accurate design and potent knockdown.

3' UTR/seed region analysis
Several studies have shown that off-target effects are frequently caused by matches of the seed region of the siR
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