Navigation Links
Exploiting the Life Science Data Explosion to Speed New Drug Discovery

This is an obvious and reasonable approach to creating a complex relational data model, and we have found that this technique is well established in its application to life sciences. Experience has shown that in the longer term, however, this approach presents us with scalability and performance issues because it relies on 3 major dependencies:

1.A consistent data set – relational integrity plays an increasingly important role as the rows in the data sets are updated and/or superceded.

2.Speed of loading – how do we take a large, structured data set into another data set with a large number of related tables/indices and, as the dataset grows, maintain an acceptable loading performance?

3.Query performance – to achieve a sufficient level of performance, we must heavily index each table in this structure, simply to reassemble the data into the form that the user will eventually require.

Nested Relational Approach
The Nested Relational approach that GE Healthcare Informatics employs is significantly simpler. Instead of trying to force square pegs into round holes and creating a large conceptual overhead, we will leave some pegs square and allow the round holes to have slightly square-like edges.

In many cases, data must be queried from the private database similarly to how it was found in the original system, but with some additional ”added value” information, such as cross functional references. To do this, we must consider the three issues identified above: we must provide a high performance load and query method that also adds inherent integrity in order to create a highly scalable, added value relational database.

By taking advantage of recent advances in database technology, we can enable a relational database to adopt an
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

Related biology technology :

1. Advantages of Roche Applied Science amplification products
2. Tools for Proteomic Science II
3. Automation of the Eppendorf Perfectprep BAC 96 DNA Kit on the Caliper Life Sciences Sciclone ALH 3000
4. World Class Life Science and Pharmaceutical Companies Leverage DoveBid s Global Reach for Asset Management and Disposition
5. HiSpeed Plasmid Kits
6. siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)
7. Rapid, High Throughput Mutation Discovery Using Fluorescent SSCP on the ABI PRISM 3100 and 3100Avant Genetic Analyzers
8. Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS
9. Increased Analyte Sensitivity through the Utility of Enhanced Mass-Resolution on the FinniganTSQ Quantum Discovery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Exploiting the Life Science Data Explosion Speed New Drug Discovery

(Date:1/14/2014)...  RXi Pharmaceuticals Corporation (OTCQX: RXII), a biotechnology company ... addressing major unmet medical needs using RNA-targeted technologies, ... Allowance from the United States Patent and Trademark ... for the treatment of fibrosis. The patent covers ...
(Date:1/14/2014)... , Jan. 14, 2014   Kinaxis ®, provider of ... ) and sales and operations planning ( S&OP ) service, ... Biomanufacturing Summit , which will be held at the Hilton ... conference, join Kinaxis customer Elisabeth Kaszas , Director of ...
(Date:1/14/2014)... January 14, 2014 Kerr Corporation, a leading ... and additional how-to information about dual arch impressions on its ... Dual Arch Impressions,” the blog entry serves up a list ... houses a step-by-step demonstration by Dr. David Little as he ...
(Date:1/14/2014)... Independent publisher Bitingduck Press, with offices in Altadena ... ideas for 2014 in production and sales of interactive ... high-quality, low-cost, DRM-free ebooks and to use the sales ... first major development will be bookstore sales in local ...
Breaking Biology Technology:RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... 21, 2011 MO BIO Laboratories, Inc., ... purification, announces the launch of the RTS DNase™ Kit, ... enzyme. (Photo: http://photos.prnewswire.com/prnh/20110921/LA65994 ) ... from RNA preparations while protecting valuable RNA samples from ...
... Silence Therapeutics plc (AIM: SLN) ("Silence", the "Group" or ... company, today announces the appointment of Tony Sedgwick PhD, ... Sedgwick will be based in Silence,s London office and ... Tony Sedgwick is an experienced biotechnology and pharmaceutical ...
... SANTA CRUZ, Calif., Sept. 20, 2011 SomaGenics, Inc., ... data on the efficacy of RNA interference (RNAi) therapeutics ... sshRNA platform. SomaGenics, along with its ... in a poster entitled "Synthetic Short shRNAs are Potent ...
Cached Biology Technology:MO BIO Laboratories, Inc. Launches the RTS DNase™ Kit 2Appointment of Chief Business Officer 2Appointment of Chief Business Officer 3SomaGenics' sshRNA Technology Demonstrates Efficacy of RNAi Against Hepatitis C Virus 2SomaGenics' sshRNA Technology Demonstrates Efficacy of RNAi Against Hepatitis C Virus 3
(Date:4/24/2014)... published in the Scientific Reports journal. , CSIC ... joint centre of CSIC and Pompeu Fabra University-UPF), explains: "When ... we saw that it did not match with the DNA ... the complete genome and to make a functional interpretation in ... Louis XVI". , The functional genome analysis was based ...
(Date:4/24/2014)... Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified ... system to discriminate between viral and endogenous RNAs ... they take control of cellular metabolism and hijack ... This process is dependent on viral RNA molecules ... of RNA viruses) and/or newly synthesized in the ...
(Date:4/24/2014)... State University and the University of North Carolina at ... could help identify arterial plaque that is at high ... stroke. , At issue is the plaque that builds ... plaque are deemed "vulnerable," meaning that they are more ... heart attack or stroke. , "Existing state-of-the-art technologies are ...
Breaking Biology News(10 mins):The blood preserved in the pumpkin did not belong to Louis XVI 2Viral infections: Identifying the tell-tale patterns 2Viral infections: Identifying the tell-tale patterns 3New ultrasound device may add in detecting risk for heart attack, stroke 2
... researchers have shown natural radioactivity within DNA can alter ... The research, recently published in Biochimica et ... at natural radioactivity within human DNA on the atomic-scale. ... as well as in every living organism across the ...
... 2013 In the past decade, a single strain of ... become the main cause of bacterial infections in women and ... a study published today in the American Society for Microbiology,s ... resistant to antibiotics, the strain H30-Rx gained an unprecedented ability ...
... climate and biosphere modelling suggests that the length of time ... known as ,residence time, - is the key "uncertainty" in ... all life - will respond to higher CO2 levels and ... time in vegetation as the negative impacts of climate change ...
Cached Biology News:Radioactivity muddles the alphabet of DNA 2Epidemic of Escherichia coli infections traced to 1 strain of bacteria 2Epidemic of Escherichia coli infections traced to 1 strain of bacteria 34 degree rise will end vegetation 'carbon sink' 24 degree rise will end vegetation 'carbon sink' 3
Mouse monoclonal [MN-8C4] to zona radiata ( Abpromise for all tested applications). Antigen: Purified eggshell proteins (zona radiata proteins and small amounts of zona pellucida proteins) from ...
Rabbit polyclonal to KIAA1276 ( Abpromise for all tested applications). entrezGeneID: 27146 SwissProtID: Q9ULE4...
Phospho-Chk1 (Ser296) Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Mouse monoclonal [CRC64] to Integrin alpha 2b + beta 3 ( Abpromise for all tested applications). Antigen: Human platelets Entrez Gene ID: 23295 Swiss Protein ID: P05106...
Biology Products: