eriencing an industrialization of what were previously cottage industries. Where it was once acceptable to depend solely on data from your own lab, it is now essential to become part of a global data community. The need to manage data in a secure, organized and controlled manner has become a major issue. Quite simply, hard coded, hand managed systems are no longer good enough. Likewise, proprietary ‘integrated warehouses’ become cumbersome and costly to manage. Such solutions simply do not scale and do not meet the ever-increasing pace of drug discovery.
Making Biological Data Accessible
In an increasingly heterogeneous world, we find data sources crossing the bounds of technology. While this has been a reality in the IT world for some time, the requirements for data integration in the life sciences arena differs from traditional IT requirements in several important ways. The IT problem is characterized by the need to deal with data held in a variety of different systems within the organization, each a controlled system. In the life sciences space, data must be integrated from internal and external sources, where external sources are public and not under the control of the using organization. Public sources are, by their nature, dynamic: constantly, new data is added and existing data updated. To complicate the picture further, the methods available to access this data are often unstable, subject to revision by the controlling agency in response to their own changing requirements.
A variety of methods are needed to make this data accessible. First, you need an architecture that removes the physical storage and access mechanisms from the usability issues. Second, you need a consistent mediation point within the architecture that accepts a single ‘language’, which can be leveraged to efficiently query against disparate data sources. Standard IT based languages are not equippedPage: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Related biology technology :1
. Advantages of Roche Applied Science amplification products2
. Tools for Proteomic Science II3
. Automation of the Eppendorf Perfectprep BAC 96 DNA Kit on the Caliper Life Sciences Sciclone ALH 30004
. World Class Life Science and Pharmaceutical Companies Leverage DoveBid s Global Reach for Asset Management and Disposition5
. HiSpeed Plasmid Kits6
. siRNA screening of the cell cycle with two dynamic GFP sensors (from Discovery Matters Issue 1, July 2005)7
. Rapid, High Throughput Mutation Discovery Using Fluorescent SSCP on the ABI PRISM 3100 and 3100Avant Genetic Analyzers8
. Quantitation of Acrylamide in Food Samples on the Finnigan TSQ Quantum Discovery by LC/APCI-MS/MS9
. Increased Analyte Sensitivity through the Utility of Enhanced Mass-Resolution on the FinniganTSQ Quantum Discovery