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Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods

M News 1991; 57: 175-82.

2. Profos Endotoxin Compendium

3. Profos Endotoxin Compendium

4. Poltorak, A. et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282(5396):2085-8.

5. Shimazu, R. et al. (1999) MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189(11):1777-82.

6. Horng, T., Barton G.M. and Medzhitov, R. (2001) TIRAP: an adapter molecule in the Toll signalling pathway. Nat. Immunol. 2(9):835-41.

7. Rietschel, E.T. and Brade, H. (1992) Bacterial Endotoxins. Sci. Amer. 267:54-61.

8. Ulmer, A.J., Flad, H., Rietschel, T. and Mattern, T. (2000) Induction of proliferation and cytokine production in human T lymphocytes by lipopolysaccharide (LPS). Toxicology 152 (1-3):37-45

9. Spectral Diagnostics Inc. Endotoxin Activity Assay. www.spectraldx.com

10. Rylander R. Endotoxin in the environment - exposure and effects. J Endotoxin Res. 2002;8(4):241-52.

11. Hartung, et al. ECVAM workshop on novel pyrogen tests based on the human fever reaction. ATLA 29, 99-123, 2001.



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