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Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

ScreenReady Targets for HTS assays.

ScreenReady Targets offer the following advantages:
Homogeneous assays with high reproducibility
Ready-to-use for radioligand binding assays
Stable for three months at 4C
Microformatted assays (25 μl or higher)
Resistant towards DMSO (1% - 5%)
Integration into automated systems such as PerkinElmers PlateTrak, MiniTrak and MultiPROBE II
Supplied with the appropriate PerkinElmer radioligand

ScreenReady Targets reagents have been developed for 21 GPCRs to date demonstrating the versatility and broad applicability of this new line of HTS reagents. Please contact us at gold.service@perkinelmer.com for an updated listing of all ScreenReady Targets available.

References

Feighner et al . (1999) Science 284, 2184-2188.

Thielemans et al . (2001) Brain Res. 895, 119-128

Tonini et al . (1996) Pharmacol. Res. 33, 217-226. Watson et al . (1994) The G-protein linked receptor Facts Book, ed. Academic Press, 1-427.

Zhang et al . (1999) J. Biomol. Screening 4, 67-73.

Related Publications

ScreenReady Targets poster presentation: Boissonneault M. et al . (2001) Development of the Motilin Receptor as a ScreenReady Targets for High Throughput Screening.


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