Navigation Links
Chemical Stability of the Brinkmann Bottletop Dispenser ,,, and the Brinkmann Bottletop Buret

Chemical Stability of the Brinkmann Bottletop Dispenser and the Brinkmann Bottletop Buret

Bottletop dispensers are used in the lab for dispensing a wide range of different solvents from glass or stainless steel containers. These dispensers have to meet various requirements. For example, they must not give off any substances which may disturb trace analysis, have cytotoxic properties, distort optical tests or influence chromatographic methods and residue analysis.

Even after prolonged contact with the solvent, the materials of the dispenser must not be affected nor bind the solvent non-specifically. This means that there are very high demands on the chemical resistance of bottletop dispensers.

The Brinkmann Bottletop Dispenser and Brinkmann ChemSaver Bottletop Dispenser are made of material which is particularly resistant to chemicals. Only parts made of PFA (perfluor alkoxy), PTFE (polytetrafluor ethylene), boron silicate glass 3.3 and platinum / iridium come into contact with the solvents. The adapter rings for the screw connection are made of PP (polypropylene).

The following pages include an example on the use of a Bottletop Dispenser for residue analysis in the lab of a food manufacturer as well as a list of the materials of which the Bottletop Dispenser is made and their chemical resistence.

Dispensing ultrapure solvents for residue analysis at the Hipp plant in Pfaffenhofen, Germany

The residue analysis of foodstuffs places high demands on the solvents and the inertness of the lab equipment used to detect, for example, even the smallest traces of pesticides.

Therefore, contamination caused by lab equipment has to be avoided under all circumstances.

A series of experiments were performed to test the suitability of the Bottletop Dispenser for food analysis. Aim: to determine whether the Bottletop Dispenser is inert to the solvents commonly used in this field.

Two examples of these experiments are described briefly below:


Test A

100 ml of the solvent acetonitrile (CH3CN) were drawn from a larger supply with a Bottletop Dispenser, evaporated in a rotation evaporator and then dissolved in 1 ml of the solvent i-octane. This sample was examined using gas Chromatography.
Result: No other peak could be found in addition to the solvent peak. Therefore, no substances had been released from the Bottletop Dispenser.

Test B

A specific amount of the herbicide atrazine (50 pg / ml) 1) was added to a sample treated as in test A as a comparative standard for pesticides. In order to detect minute amounts of pesticide, the background in the chromato-gram must consistently be as low as possible.
Result: The atrazine peak can be clearly seen in the chromatogram without any ghost bands. This shows that minute amounts of pesticides can be detected with this system.

1) (EG drinking water limit: 100 pg / ml) signal time solvent peak A signal time solvent peak B Atrazine peak

For each chemical, 2 figures are stated. The figure on the left is stability at a test temperature of +20C, the figure on the right is the stability at +50C. Salts were tested as almost saturated solutions. All data are recommondations without guarantee. 1 = resistant 2 = sensitive (raw material is affected after longer contact) 3 = incompatible

CHEMICALS PFA PTFE Boron silicateglass 3.3 Bottletop Buret & Dispenser can be used PP Adapter rings
Acetaldehyde 1 / 1 1 / 1 1 / 1 1 / 1 1 / 3 *1
Acetic acid, 50% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Acetone *5 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Acetonitrile *5 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Acrylonitrile 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Adipic acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Allyl alcohol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Aluminum chloride 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Aluminum hydroxide 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Amino acids 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Ammonia 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Ammonium chloride 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Ammonium hydroxide, 30% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
n-Amyl acetate 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Amyl alcohol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Amyl chloride 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Aniline 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Aqua regia *2 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Barium chloride (BaCl2) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Benzaldehyde 1 / 2 1 / 1 1 / 2 1 / 1 1 / 1
Benzene 1 / 1 1 / 1 1 / 1 1 / 1 1 / 2 *1
Benzine 1 / 1 1 / 1 1 / 1 1 / 1 2 / 2 *1
Benzyl alcohol 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Biuret reagent 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Boric acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Bromine 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Bromoform (Tri Methanbromid) 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1

n-Butanol

1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
n-Butyl acetate 1 / 1 1 / 1 1 / 1 1 / 1 2 / 2 *1
Calcium chloride 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Carbon disulphide 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Carbon tetrachloride 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Chloroacetic acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Chromic acid, 10% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Chromic acid, 50% *2 1 / 1 1 / 1 1 / 1 1 / 1 2 / 2 *1
Chromic sulfuric acid, concentrated *2 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Cresol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 2 *1
Cupric sulphate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Decahydronaphtalene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Dibutyl phtalate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 2 *1
Dichlorobenzene 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Dichlorethane (Ethyl dichloride)*5 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Dichlormethane (Methylene chloride)*5 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Diethylene glycol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Diethyl ether 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Dimethylformamide 1 / 1 1 / 1 1 / 1 1 / 1 1 / 3 *1
1.4-Dioxan 1 / 1 1 / 1 1 / 1 1 / 1 2 / 2 *1
Ethanol 100% (Ethyl alcohol) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Ethyl acetate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Ethylene oxide 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Formaldehyde, 40% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Formic acid, 98-100% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Fuel oil 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Glycerol *4 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Glycol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
n-Hexane 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Hydrochloric acid 35% *5 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Hydrochloric acid 37% *5 1 / 1 1 / 1 1 / 1 1 / 1 1 / 3 *1
Hydrofluoric acid, 40% 1 / 1 1 / 1 3 / 3 3 / 3 1 / 1
Hydrogen peroxide, 30% *3 1 / 1 1 / 1 1 / 1 3 / 3 1 / 1
Iodine-Potassium iodide sol. 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Isobutanol (Isobutyl alcohol) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Isopropanol (Isopropyl alcohol) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Isopropyl benzene 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Lactic acid / Lactate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Magnesium chloride (MgCl) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Mercury 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Mercury (I) chloride 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Methanol (Methyl alcohol) *5 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Methyl propyl ketone 1 / 1 1 / 1 1 / 1 1 / 1 1 / 2 *1
Nitric acid, 10% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Nitric acid, 50% 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Nitric acid, 70% 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Nitrobenzene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Octane / iso octane 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Oil of turpentine 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Oxalic acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Pentane (n- / Iso-) *5 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Perhlorethylene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Perchloric acid, 10% 1 / 2 1 / 1 1 / 1 1 / 1 1 / 3 *1
Phenol, 100% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Phosphoric acid, 85% 1 / 1 1 / 1 2 / 3 2 / 3 1 / 1
Potassium chloride 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Potassium hydroxide , 50% 1 / 1 1 / 1 1 / 2 1 / 2 1 / 1
Potassium permanganate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Propanol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Propylene glycerol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Propylene oxide 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Pyridine 1 / 1 1 / 1 1 / 1 1 / 1 2 / 2 *1
Salicylaldehyde 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Salicylic acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Scintillation cocktail 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Silver acetate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Silver nitrate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Sodium acetate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Sodium dichromate 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Sodium hydroxide, 50% 1 / 1 1 / 1 1 / 2 1 / 2 1 / 1
Sulphuric acid, 60% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Sulphuric acid, 98% 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Tartaric acid 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Tenside (Tween-, Trition X-, Brij-dilutions) 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Tetrachloroethylene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Tetrahydrofuran 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Toluene 1 / 1 1 / 1 1 / 1 1 / 1 2 / 3 *1
Trichloroacetic acid, 10% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Trichloroethane 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Trichloroethylene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Trichlorofluorethane *5 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Tricloromethane (Chloroform) *5 1 / 1 1 / 1 1 / 1 1 / 2 2 / 2 *1
Triethylene glycol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Trifluoroacetic acid (fuming; strongest of halogenized acids)*5 3 / 3 1 / 1 3 / 3 3 / 3 3 / 3
Tripropylenglycol 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Urea 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Vinylidene chloride 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Xylene 1 / 1 1 / 1 1 / 1 1 / 1 3 / 3 *1
Zinc chloride, 10% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
Zinc sulphate, 10% 1 / 1 1 / 1 1 / 1 1 / 1 1 / 1
*1 PTFE adapter available
*2 Pt-Ir can be easily loosened from the srping
*3 catalytic reaction with Pt-Ir spring
*4 Liquid with high viscosity
*5 Liquid with high vapor pressure; gases leak (observe safety regulations)

Materials

Part Bottletop Dispenser ChemSaver Bottletop Dispenser Bottletop Buret Direct contact to dipensing fluid Valve block PFA PFA PFA Valve cock PTFE PTFE/PFA Filling valve ETFE ETFE ETFE Discharge valve ETFE ETFE/PFA ETFE/PFA Discharge valve PFA PFA PFA Spring for valve Pt-Ir Pt-Ir Valve ball Borosilicate (DURAN) Borosilicate (DURAN) Borosilicate (DURAN) Cylinder Borosilicate (DURAN) Borosilicate (DURAN) Borosilicate (DURAN) Telescopic filling tube FEP FEP FEP Indirect contact to dipensing fluid Piston (2.510 ml) PFA PFA PTFE/PFA Piston (25100 ml) ETFE ETFE Piston holder PP PP PTFE Cylinder casing PP PP PTFE/PFA Protective cylinder sleeve PTFE PTFE Valve block housing PP PP PP Discharge tube sleeve PP PP PP Discharge tube cap PVDF Air vent cup PP PP PP Volume adjustment knob PP PP O-ring for valve cock protection Viton Viton Viton Volume setting knob PP PP Discharge valve toggle PP PP PP Drying tube PP PP PP Wheel PP Display foil PE DURAN Borosilicate 3.3 PE Polyethylene ETFE Tefzel ETFE (Ethylene tetrafluorethylene) PTFE Polytetrafluoroethene FEP Teflon FEP (Tetrafluoroethylene perfluoropropylene) PVDF Polyvinylidene fluoride PFA Teflon PFA (Perfluoro-alkoxy-PTFE-Copolymer) Pt-Ir Platinum-Iridium PP Polypropylene
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

Related biology technology :

1. Chemical Stability of Disposables
2. Efficient Delivery of siRNAs to Human Primary Cells: Electroporation vs. Chemical Transfection
3. Optimizing Chemical Transfection and Electroporation of siRNAs
4. Determination of N-nitrosamines in Baby Bottle Rubber Teats by Liquid Chromatography-Atmospheric Pressure Chemical Ionization Mass Spectrometry
5. Screening of Corticosteroids in Urine by Negative Atmospheric Pressure Chemical Ionization LC/MS/MS
6. Direct On-Membrane MS/MS Analysis using the Chemical Printer (CHIP-1000) and AXIMA-QIT
7. DNA Stability with Oragene
8. Ergonomics and Liquid Handling How can BrinkmannTM Help ?
9. Brinkmann/Eppendorf SOP Standard Operating Procedure for Pipettes
Post Your Comments:
(Date:11/21/2014)... The California Healthcare Institute ... representing leading California academic institutions, biotechnology, medical device, ... today released a report revealing that California ... The trend shows a 4 percent increase between ... Industry Report indicates that, while biopharmaceutical and ...
(Date:11/21/2014)... (PRWEB) November 21, 2014 2014 ... Ferrocyanide Industry” is a professional and in-depth research ... Sodium ferrocyanide information, like its definition, classification, ... industry overview. This report covers the international market ... global (such as the US, Europe, Asia, China, ...
(Date:11/21/2014)... ON , Nov. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ... and nine month periods ended September 30, 2014.  Biorem,s complete 2014 ... ( www.sedar.com ). Financial Summary:Three-months ended September ... except per share data) , 2014 , ... 2,282 , 5,281 , 6,715 ...
(Date:11/18/2014)... Diego, CA (PRWEB) November 17, 2014 Athena ... of Salk , Dr. Beverly Emerson, a professor in the ... of genes. Her most recent discovery points to an “off ... Dr. Emerson’s career and how her local research is making ... will present her findings and then join host Cheryl K. ...
Breaking Biology Technology:California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 2California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 3California Healthcare Institute and PwC Report Boom in California’s Biomedical Industry 4Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 2Sodium Ferrocyanide Market: Analysis for Global & China Regions Development Trends Available at DeepResearchReports.com 3Biorem Reports Third Quarter Results 2Biorem Reports Third Quarter Results 3
... (Amex: IMA ) today announced that it has ... Australian company traded on,the Australian Securities Exchange, under which ... issued shares in Panbio for AUD 0.65 cash,per share. ... of,Panbio at approximately AUD 41 million, or approximately USD ...
... ExL Pharma, Cision and the PRSA have,joined ... biotech,public relations executives the first Pharmaceutical Public Relations,Symposium ... This,one-day event will cover the key issues and ... is under ongoing political and media scrutiny,most notably ...
... USC,s Increased Commitment to Research Advancements in Health ... Robust Life Science Industry in Los Angeles, LOS ... University of Southern California,s strengthened,commitment to advancing breakthrough research ... today the opening of an office,in the new Harlyne ...
Cached Biology Technology:Inverness Medical Innovations Agrees to Acquire Panbio Ltd. 2Leading Pharmaceutical Communication Executives Gather for the 1st Annual Pharmaceutical Public Relations Symposium 2The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 2The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 3The USC Stevens Institute for Innovation Opens Shop on US Health Sciences Campus 4
(Date:11/6/2014)... when that predator runs so fast that it essentially blinds ... the fastest creature on Earth. Some of these half-inch-long beetles ... miles per hour). The fastest human can do about five ... beetle, a person would have to hit 480 miles per ... peak speeds, everything becomes a blur. They can,t gather enough ...
(Date:11/5/2014)... Santamaria, associate professor of biology in the UTSA ... in the nation selected to receive a two-year ... for Exploratory Research (EAGER). The funding supports President ... researchers to create new technology that will demystify ... complex behaviors in neuroscience are broken into the ...
(Date:11/5/2014)... Janeiro, Brazil -Individuals show great diversity in their ability ... and females greatly differ in their perceptual evaluation of ... smell tests. , Sex differences in olfactory ... and may be connected to one,s perception of smell, ... Thus, women,s olfactory superiority has been suggested to be ...
Breaking Biology News(10 mins):The tiger beetle: Too fast to see 2UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3The female nose always knows: Do women have more olfactory neurons? 2
... green tea dramatically boosted production of a group ... levels of these beneficial proteins, according to researchers ... published in the August issue of Cancer Epidemiology, ... Association for Cancer Research, suggest that a green ...
... has shattered a long-held belief that no direct pathway ... cell nucleus. (The cell is the smallest metabolically functional ... material outside of a cell can migrate into a ... phagocytosis, in which extracellular material is captured by a ...
... Alcohol and smoking can be harmful, if not deadly. ... environmental cues, genomic factors also play an important role. The ... complex interactions with the environment. Adoption and twin studies have ... be inherited. Such studies have provided evidence that ones sex ...
Cached Biology News:Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless 2New, more direct pathways from outside the cell-to-cell nuclei discovered 2New, more direct pathways from outside the cell-to-cell nuclei discovered 3Does the desire to consume alcohol and tobacco come from our genetic makeup? 2Does the desire to consume alcohol and tobacco come from our genetic makeup? 3
...
... high-density serum biomarker chip to profile the ... antibody chip containing 120 human cancer serum ... biomarker discovery scientists to study panels of ... therapy and the likelihood of recurrence of ...
... Ventilates and removes chemical fumes, ... exhaust. Bonded charcoal filters remove ... ensure safe exhaust flow speed ... access opening. Includes air speed ...
Sigmas E-TOXATE (Limulus Amebocyte Lysate) test kits are intended for the detection and semiquantitation,of endotoxins for research purposes....
Biology Products: