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COSMCPREP HIGH AND LOW COPY PLASMID PURIFICATION

CosMCPrep is a versatile SPRI-based, plasmid purification system that uses a single protocol to purify a variety of high and low copy number template types. This flexible system is easily automated and produces high quality templates. The single protocol, ease of automation and high quality results make CosMCPrep an ideal solution for all template purification needs.

COSMCPREP FEATURES
  • High quality plasmid purification
  • Single protocol for all template types
  • Fully automated protocols
  • No centrifugation or filtration steps
  • Superior downstream sequencing results

    FLEXIBLE PURIFICATION

    CosMCPrep can be used for purification of:
  • BACs
  • Cosmids
  • Fosmids
  • Low copy plasmids
  • High copy plasmids





    LOW COPY PLASMID PURIFICATION

    Purification of low copy plasmids can be challenging due to the low numbers per cell. CosMCPrep enables efficient, fully-automated purification of low copy plasmids such as fosmids (Figure 1) and BACs. CosMCPrep-purified plasmids are high quality and result in improved sequencing performance (Figure 2). Figure 3 shows a BAC end sequence with a Phred20 read length of 700bp.

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