Navigation Links
Assess the In Vivo Activation of Signal Transduction Pathways with,,,PathDetect Reporting Systems

which is convenient, sensitive, and quantitative. The plasmids included in the PathDetect reporting systems are highly purified, functionally tested, and transfection ready; all plasmids can be purchased separately.

Table 1: Pathways Available

Pathway

Transcriptional Activator

PathDetect System

Plasmids available

JNK (c-Jun N-Terminal Kinase)

c-Jun

PathDetect c-Jun Trans-Reporting System

pFA2-cJun plasmid
pFC-MEKK plasmid

MAPK (Mitogen-Activated Protein Kinase)
and JNK

Elk1

PathDetect Elk1 Trans-Reporting System

pFA2-Elk1 plasmid
pFC-MEK1 plasmid

PKA
(Cyclic AMP-Dependent Protein Kinase)

CREB

PathDetect CREB Trans-Reporting System

pFA2-CREB plasmid
pFC-PKA plasmid

p38 MAP Kinase

CHOP

PathDetect CHOP Trans-Reporting System

pFA-CHOP
pFC-MEK3

Uncharacterized pathway

c-Fos

pFA-cFos

Uncharacterized pathway

ATF2

pFA-ATF2

REFERENCES

  1. Karin, M. and Hunter, T. (1995) Curr. Biol. 5: 747-757.

  2. Boulikas, T. (1995) Crit. Rev. Eukaryot. Gene Expr. 5: 1-77.

  3. Wingender, E. (1990) Crit. Rev. Eukaryot. Gene Expr. 1: 11-48.

  4. Treisman, R. (1996) Curr. Opin. Cell Biol. 8: 205-215.

  5. Xu, L., S
    '"/>



Source:


Page: All 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats
2. An Assessment of the Eppendorf twin.tec plate performance in PCR* applications
3. A New Way to Assess siRNA Delivery Efficiency
4. Assessing Gene Function with siRNA Libraries
5. Fast, Accurate Assessment of siRNA-induced Gene Silencing
6. Qualitative and Quantitative Assessment of Plasmid DNA Isolation, Rev A
7. Assessing UV damage of hair
8. Caspase-3 Activation - An Indicator of Apoptosis in Image-Based Assays
9. Ca++-Induced G Protein Coupled Receptor (GPCR) Activation Monitored via Aequorin Luminescence in the LMax Microplate Luminometer (MaxLine Application Note #42)
10. Optimizing Transfection Conditions for Studying Signal Transduction Pathways
11. Signal Transduction Reporting Systems Using Cis-Acting Enhancer Elements
Post Your Comments:
(Date:12/4/2008)...ent Construction of Synthetic Genomes , , ...Researchers at the J. Craig Venter Institute (JCVI... have published a paper describing a significant a...w assemble the whole bacterial genome, Mycoplasma.... Lead author Daniel G. Gibson, Ph.D. and his team...
(Date:12/4/2008)...r 4 AC Immune SA, a leader,in Alz... that the World,Economic Forum has elected AC Imm...ments as an innovation leader and for its breakthr...business and society. , Furthermore, AC Imm...cal,milestones in the development of innovative t...
(Date:12/4/2008).../ -- Azur Pharma Limited ("Azur") today,announced...ith BioSante,Pharmaceuticals, Inc ("BioSante")(Na...(TM). Elestrin is a fast drying gel formulation of...f moderate to severe vasomotor symptoms,associate.... Food and Drug,Administration ("FDA") in Decembe...
(Date:12/4/2008)...irstCall/ -- Delcath Systems, Inc. (Nasdaq: DCTH...., has stepped down from his position as a directo... Lewis advised the Company that his decision to le...mmitments to new leadership positions. , , ...118/NY46990LOGO ) , , Dr. Harold Koplewicz,...
Breaking Biology Technology:J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology 2J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology 3J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology 4J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology 5Technology Pioneer 2009 - AC Immune Highlights Significant Clinical Milestones in Alzheimer's Disease Drug Development 2Azur Pharma Ltd. Enters Into Definitive Agreement With BioSante Pharmaceuticals Inc [nasdaq: BPAX], to Acquire U.S. Rights to Elestrin (TM) 2Jonathan Lewis, M.D., Ph.D. Steps Down From Delcath Systems Board of Directors 2
...for 100 mg tissue samples. Mouse kidney, , ...y extracted with approximate , yields of 70...terials , , , ...zor blade or scissors , 55C inc...lease-free 2.0 ml microfuge , t...
...storage , solution that stabili... tissues. (Ambion,s new RNA later -ICE is...e with frozen tissues - see "<A , ...ml">Stop , Grinding Frozen Tiss... harvested and immediately submerged in RNA l...
...THIS ARTICLE: <A , href="#2...href="#3">RNA , Isolation, Probe Gene...ophoresis, , Transfer > <A , ... Detection > <A , href="#6">S..., , , Northern an...
...th fluorescent , dyes (i.e. Cy3 or Cy... directly incorporated during cDNA synthesis,...reverse transcription (RT) reaction, or attached v...formed after any enzymatic reactions , ...nzymatic , incorporation of a Cy-labe...
Other Biology Technology:Genomic DNA Preparation from RNAlater Preserved Tissues 2Genomic DNA Preparation from RNAlater Preserved Tissues 3RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 2RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 3RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 4RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 5RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 6RNArticles: Keeping RNA Intact Prior to RNA Isolation - RNAlater 7Northern Analysis: The Basics 2Northern Analysis: The Basics 3Northern Analysis: The Basics 4Northern Analysis: The Basics 5Northern Analysis: The Basics 6Northern Analysis: The Basics 7Northern Analysis: The Basics 8Northern Analysis: The Basics 9Northern Analysis: The Basics 10Northern Analysis: The Basics 11Northern Analysis: The Basics 12Northern Analysis: The Basics 13Northern Analysis: The Basics 14Northern Analysis: The Basics 15Northern Analysis: The Basics 16Northern Analysis: The Basics 17Northern Analysis: The Basics 18Northern Analysis: The Basics 19Amino Allyl Labeling for Array Analysis 2
(Date:12/3/2008)...rd H. Jones, deputy executive director of the Inte...nergy Outlook 2008" Dec. 9 at Rice University,s Ba...dress such questions as: Is the world facing a sup...ment? What type of post-Kyoto policy framework mig... levels, and what impact might such a policy frame...
(Date:12/3/2008)...SVILLE, Fla. The wild pea pod is big and heavy, w...of its parent plant. , And yet, like a grounded ...it manages if it has a reasonable chance of escap...t the world,s largest experimental landscape devot...s or other natural areas have discovered the pea ...
(Date:12/3/2008)... a harmless virus to insert a corrective gene into...n,s Research Hospital have alleviated sickle cell ...rs found that the treated mice showed essentially ...tists caution that applying the gene therapy to hu...y believe that the new therapy will become an impo...
(Date:12/3/2008)...ti-institution team of investigators led by resear...sity of Southern California (USC) has received $19...f Mental Health (NIMH) for a groundbreaking effort...ds of patients in order to study the genetic risks...USC Center for Genomic Psychiatry and Massachusett...
Breaking Biology News(10 mins):'World Energy Outlook' to be presented at Rice University Dec. 9 2Rooted plants move mysteriously down greenways, scientists say 2Rooted plants move mysteriously down greenways, scientists say 3Gene therapy corrects sickle cell disease in laboratory study 2Gene therapy corrects sickle cell disease in laboratory study 3USC researchers head global effort to study genetic risks that contribute to psychiatric diseases 2USC researchers head global effort to study genetic risks that contribute to psychiatric diseases 3Nutraceutical to Present at Canaccord Adams Healthy Living Conference 27315 1Nutraceutical to Present at Canaccord Adams Healthy Living Conference 27315 2Nutraceutical to Present at Canaccord Adams Healthy Living Conference 27315 3Sunlight exposure plus low antioxidant levels may place older adults at risk for eye disease 27311 1Sunlight exposure plus low antioxidant levels may place older adults at risk for eye disease 27311 2Hospital based smoking cessation program after heart attack adds to success 27308 1Carnegie Mellon International Autism Symposium to Feature Groundbreaking Research Oct 17 18 27307 1Carnegie Mellon International Autism Symposium to Feature Groundbreaking Research Oct 17 18 27307 2
...gists have learned where and how some plant seeds ...rking to improve the iron content of plants. Their...ron deficiency and malnutrition in humans. , The t...scular system of the seed of Arabidopsis, a model ...red in the vacuole, a plant cell,s central storage...
... the latest in high tech tools, researchers have i...ve of chronic lung rejection up to 20 months befor...ts have the highest mortality rate of organ recipi...gator and pulmonologist Chris Wendt. Currently, th...s will fail, and when signs of chronic rejection a...
...tists have answered a long-standing molecular stum...olecule bend and coil without requiring large amou...from the United States and the Netherlands, led by...DNA is much more flexible than previously believed... used a technique called atomic force microscopy t...
...ungs of patients suffering chronic obstructive pul...astic fibers, a new finding that contradicts the c...t lung. , The study "Evidence for attempted region...done by Jason Woods, Kristin Castillo, Alexander P...ty, St. Louis, Mo.; Joel Cooper of the University ...
Other Biology News:Plant studies reveal how, where seeds store iron 2Proteins may predict lung transplant rejection 2Proteins may predict lung transplant rejection 3Penn researcher shows that DNA gets kinky easily at the nanoscale 2Lungs try to repair damaged elastic fibers 2
SAGE (serial analysis of gene expression) technology allows comprehensive genome-wide expression analysis. Expression profiles generated by SAGE are sensitive enough to detect low-abundance transcrip
Sheep Serum US Origin
...or the ultimate in utility and flexibility press-t...t the needs of the researcher. They are available ...as sheet material that can be easily trimmed to pr...utoclavable and non-cytotoxic and can be used to i...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine.
Biology Products: