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Anti-NMDAR2A recognizes a predominant band, migrating at approximately 180 kDa, from a rat brain homogenate preparation. In immunoprecipitation experiments, this antibody does not cross-react with NR2B or NR2C. Strong and specific immunolabeling was also demonstrated for Anti-NMDAR2B. Anti-NMDAR2C can be used as a pan antibody for all three proteins, as it labels a 140-kDa, NR2C band and 180-kDa, NR2A and NR2B bands.
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