Navigation Links
Antibodies for Studying NMDA Receptor Protein Expression and,,,Synapse-Specific Immunolabeling

New antibodies for neuroscience research


Danny Q. Hoang Michael Browning Xinping Yang Peter Pingerelli
Stratagene Cloning Systems, Inc.


Stratagene introduces affinity purified antibodies for NMDA receptor subunits that are useful for studying expression of the NR2A, NR2B and NR2C subunit proteins in different cell types and brain regions. These antibodies have been used in Western blot analysis of rat brain to study expression of specific NMDA receptor subunits. In addition, these antibodies can be used for immunoprecipitation and immunohistochemistry. Stratagene also introduces an antibody for synapsin I, the synapse-specific protein, that is useful for studying synaptogenesis and synapse elimination.

Glutamate is a major excitatory neurotransmitter in the mammalian central nervous system. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). The NMDAR plays a critical role in long-term potentiation (LTP), a putative cellular substrate of memory.1 This receptor has also been linked to conditions involving injury neurotoxicity and in pathological states, such as epilepsy and Parkinsons, Huntingtons and Alzheimers diseases.2

Molecular cloning studies indicate that five NMDA receptor genes exist, including NMDAR1 (NR1) and four NR2 subunits (NR2A-D).3 When reconstituted in vitro, the functional properties of neuronal NMDAR appear to be conferred by the combination of an NR1 subunit with any of the four NR2 subunits.4 In addition, there are a number of different splice variants of the N
'"/>

Source:


Page: All 1 2 3 4

Related biology technology :

1. Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
2. Optimizing Transfection Conditions for Studying Signal Transduction Pathways
3. Enzyme Immunoassay for Studying Intracellular Levels of cAMP
4. New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction Pathways
5. New Fusion Trans-Activator Plasmids for Studying Signal Transduction Pathways
6. Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue
7. pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins
8. Gene-Specific Primers for NMDA Receptor Subunits
9. TKB1 Cells Identify Receptor Tyrosine Kinase Interacting Proteins
10. Quantification of the Purinergic Receptor P2X3 using ICAT and Orthogonal 2D LC-MS/MS with an Ion Trap Mass Spectrometer
11. Isolation of Low Molecular Weight Digestion Products of the Human Platelet Thromboxane A2 Receptor, Rev A
Post Your Comments:
(Date:2/25/2015)... 25, 2015 truBrain , creator ... in this week,s Power Pitch segment of CNBC,s  ... the company,s traction and growth strategy, as well ... funding site CircleUp. The segment highlights ... validated by neurotechnology, while also discussing its decision ...
(Date:2/25/2015)... KONG, Feb. 25, 2015 China Cord Blood ... "Company"), China,s leading provider of cord blood collection, laboratory ... services, today announced its preliminary unaudited financial results for ... 2015 ended December 31, 2014. Third Quarter ... third quarter of fiscal 2015 increased by 10.7% to ...
(Date:2/25/2015)... Salt Lake City, Utah (PRWEB) February 25, 2015 ... was recently awarded a $604,000 grant from ... Science, Technology, Engineering, and Mathematics (STEM) program. , ... students demonstrating a financial need, enabling them to ... or bachelor’s degree in a STEM discipline. Institutions ...
(Date:2/25/2015)... NY (PRWEB) February 25, 2015 ... Reality” conference will take place on March ... Medicine in New York City. This single-day conference ... key investors, and other stakeholders to discuss in-depth ... field of cancer immunotherapy. The conference format is ...
Breaking Biology Technology:CNBC's Power Lunch Features Neurotechnology Start-up truBrain 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 2China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 3China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 4China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 5China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 6China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 7China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 8China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 9China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 10China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 11China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 12China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 13China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 14China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 15China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 16China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 17China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 18China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 19China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 20China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 21China Cord Blood Corporation Reports Financial Results for the Third Quarter and First Nine Months of Fiscal 2015 22SLCC Receives $600K National Science Foundation Grant 25th Annual "Cancer Immunotherapy: A Long- Awaited Reality" Conference Taking Place March 26, 2015 in New York City 25th Annual "Cancer Immunotherapy: A Long- Awaited Reality" Conference Taking Place March 26, 2015 in New York City 3
... Ltd, a specialty,biopharmaceutical company focused on controlling ... successfully raised GBP11 million ($21.8,million) in an ... new investors Goldman Sachs and Invesco Perpetual, ... and Lansdowne,Partners., "Completing this financing is ...
... at Northwestern Universitys Center for Quantum Devices (CQD) ... detecting single photons in the ultraviolet region (360-200 ... only available technology in the short wavelength UV ... detection sensitivity. However, these fragile vacuum tube devices ...
... Researchers at Rensselaer Polytechnic Institute and Polyset Company ... could lead to dramatic cost savings and efficiency ... , Along with allowing enhanced performance and cost ... called polyset epoxy siloxane (PES), should also enable ...
Cached Biology Technology:Circassia Raises GBP11 Million ($21.8 Million) in Oversubscribed Second Round Funding 2Tiny avalanche photodiode detects single UV photons 2New polymer could improve semiconductor manufacturing, packaging 2
(Date:2/18/2015)... , Feb. 18, 2015  Cepheid (NASDAQ: CPHD ... the following conferences, and invited investors to participate via webcast. ... Boston, MA Tuesday, March 3, 2015 at 11.20 ... Orlando, FL Wednesday, March 4, 2015 ... To access the live webcasts for these events, please visit ...
(Date:2/11/2015)... , February 11, 2015 ... research report "Access Control Market by Product (Cards and ... Residential, Military and Defense, Government, Industrial, Healthcare, Education) and ... published by MarketsandMarkets, the Access Control Market ... 2020, growing at a CAGR of 10.6% ...
(Date:2/5/2015)... 5, 2015  Marken is starting its 35 th ... launched a new marketing campaign to solidify its place ... new campaign focuses on First as a ... The first headline in the series, ... with its client,s priorities. Marken recognizes the need to ...
Breaking Biology News(10 mins):Cepheid to Webcast Upcoming Financial Presentations 2Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken Launches New Patient-Centric Campaign 2
... The same mechanism that stabilises the DNA in the ... function of vertebrate muscle cells. This has been established ... of Physiology) in cooperation with American and German colleagues. ... Hsp90, which then forms a complex with the muscle ...
... paddy fields in Japan with salty sludge, scientists are near ... collaboration, a new method for marker assisted breeding is being ... traits such as salt tolerance. Details of the new method, ... on Sunday so they can be used by scientists and ...
... work with engines traveling on straight tracks, a team ... Oxford have successfully used DNA building blocks to construct ... tracks with multiple switches. The findings, published in the ... Nanotechnology , are expected to lead to further developments ...
Cached Biology News:How protein networks stabilize muscle fibers: Same mechanism as for DNA 2Science to help rice growers affected by Japan's tsunami 2