The limit of detection (LOD) is estimated to be <30 fg/μL in solution corresponding to a LOD of <3 pg/g in shrimp according to the U.S. FDA method.
The choice of either product ion for quantitation is especially important when complex matrices interfere with one of the product ions. The Varian 1200L LC/MS/MS system demonstrates excellent sensitivity, reproducibility and performance for the analyses of chloramphenicol and is able to assist in the detection of potentially harmful substance in food imports/ exports to improve food safety throughout the world.
1. B.K. Neuhaus, J.A. Hurlbut. and W. Hammack LC/MS/MS Analysis of Chloramphenicol in Shrimp. U.S. FDA Laboratory Information Bulletin No. 4290, Volume 18, No. 9, September 2002 .