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A simple and rapid LC-MS/MS method for the simultaneous determination of nine antiretroviral drugs commonly used in Europe (protease Inhibitors and non-nucleoside reverse transcriptase inhibitors)

tion of antiretrovirals by liquid chromatography-tandem mass-spectrometry. Clinical Biochemistry 2002; 35:99-103.

2. Ghoshal AK, Soldin SJ. Improved Method for Concurrent Quantification of Antiretrovirals by LC-MSMS. Therapeutic Drug Monitoring 2003; 25:541-543.

3. Koal T, Dieters M, Casetta B, Kaever V. Simultaneous determination of 4 immunosuppressants by means of high speed and robust on-line SPEHPLC- MSMS. Journal of Chromatography 2004; B, 805:215-222.

Acknowledgements

Applied Biosystems/MDS SCIEX acknowledges Hlne Belva-Besnet and Bruno Casetta, and our collaborators Maryse Gravier, Yves Tavet and Didier Olichon from Laboratoire Pasteur Cerba, Cergy Pontoise, France, for providing the method, samples and data for this application note.


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