Navigation Links
A new wide field-of-view confocal imaging system and its applications in drug discovery and pathology

and drug effects in humans, is increasingly being used for testing in drug discovery. Zebrafish have all of the equivalent organs found in mammals, and most human genes have homologues in zebrafish.60-62

Figures 10 - 13 are inverted fluorescence images of coronal sections of zebrafish larvae stained with H & E, plastic sectioned at 1 μm thickness. Figure 10 is an overview image of the slide taken using a green (535 nm) laser and a 700/75 nm bandpass emission filter. There are six larva sections in it. Figure 11 is an overview of the inverted fluorescence image of one of the zebrafish larva sections in Fig. 10, depicting entire organism in a coronal section. It is recorded with green laser (532 nm) excitation and a 570/50 nm bandpass emission filter, at 0.5/0.25 μm optical/pixel resolution. Figure 12 is a transposed and magnified part of the fluorescence image in Fig. 11. This section view depicts lower coronal section of the transition region from pharyngeal portion to abdomen of the zebrafish larva. Figure13 is the actual pixel image of an eye of the zebrafish larva shown in Fig. 11. The overlaying cornea, round lens and retinal layers are observed clearly.

3.3. Whole Mouse Section Imaging

Figures 14 - 17 are inverted fluorescence images of or a part of a sagittal whole mouse section stained with Thioflavin-S. The images were recorded using green (535 nm) laser excitation and 700/75 nm bandpass emission filter. Figure 14 is an overview of a 20 by 65 mm whole mouse section on a standard microscope slide (25.4 by 76.2 mm) at 2.0/1.0 μm optical/pixel resolution, showing the entire saggital section with the anterior (head) end on the right and the (posterior) tail end on the left s
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31

Related biology technology :

1. Kodak in vivo imaging system: precise coregistration of molecular imaging with anatomical X-ray imaging in animals
2. Rapid hit confirmation and early hERG liability testing using the IonWorks HT system
3. High-content screening of GPCR activation with MetaXpress, AcuityXpress and the Transfluor assay system
4. Matched siRNAs and Assays: Ambion + Applied Biosystems = RNAi Success
5. Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system
6. Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system
7. Multiplex protein detection with the ECL Plex fluorescent Western blotting system using the Ettan DIGE Imager
8. Performance of Ad-A-Gene Cyclic AMP Response Element-Nitroreductase (CRE-NTR): an adenoviral vector gene delivery system
9. Amplified Fragment Length Polymorphism (AFLP) Analysis on Applied Biosystems Capillary Electrophoresis Systems
10. A technique for increasing yields in bioreactors and disposable cell-culture systems
11. An Assessment of the Eppendorf twin.tec plate performance in PCR* applications
Post Your Comments:
(Date:9/17/2014)... 2014 The global consumption of squalene / squalane ... a natural skin-identical chemical that finds applications in various end ... pharmaceuticals, and in other applications like high grade lubrication, and ... few major players and is regionally segregated. Sophim ( ... Co. Ltd. ( Japan ), SeaDragon Marine Oils ...
(Date:9/17/2014)... , Sept. 17, 2014  MiMedx Group, Inc. ... processor and marketer of patent protected regenerative biomaterials ... today the publication of another peer-reviewed clinical study.    ... A Multi-center Randomized Controlled Clinical Trial Evaluating the ... Membrane Allografts and Multi-layer Compression Therapy vs. Multi-layer ...
(Date:9/17/2014)... Franklin, MA (PRWEB) September 17, 2014 ... pre-engineered version of its TerraPure tank . This ... tanks is molded from FDA-compliant linear polyethylene and available ... seven pre-installed fittings and ships in two weeks or ... same features and benefits found in Terracon’s existing TerraPure ...
(Date:9/17/2014)... SAN FRANCISCO, Calif. , Sept. 17, 2014 /PRNewswire/ ... ), a molecular diagnostics company pioneering the field of ... Hall to chief operating officer. Mr. Hall ... spearhead the company,s commercial entry into endocrinology. Since 2012, ... operations, as well as managed care and billing functions. ...
Breaking Biology Technology:Squalene Market by Source (Animal & Vegetable) & by End-user Industry (Cosmetics, Pharmaceuticals & Food Industry) - Global Trends & Forecasts to 2019 2Squalene Market by Source (Animal & Vegetable) & by End-user Industry (Cosmetics, Pharmaceuticals & Food Industry) - Global Trends & Forecasts to 2019 3MiMedx Multi-Center Randomized, Controlled VLU Clinical Study Published In Peer-Reviewed Journal 2MiMedx Multi-Center Randomized, Controlled VLU Clinical Study Published In Peer-Reviewed Journal 3MiMedx Multi-Center Randomized, Controlled VLU Clinical Study Published In Peer-Reviewed Journal 4Terracon Introduces Pre-Engineered TerraPure® Tank for Ultrapure Water Applications 2Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 2Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 3Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 4
... Collaboration will leverage HUYA,s growing Chinese bioscience network , ... 15 HUYA Bioscience International, a leader in US/China ... subsidiary, N.V. Organon. Schering-Plough has selected HUYA to identify ... lead, preclinical and clinical drug candidates in specific therapeutic ...
... VIENNA, Austria, December 15 bwin, the world,s,leading online ... Health Alliance, a Harvard Medical School Teaching Affiliate, have,just ... The,research objective is to use scientific evidence to create ... of the,world,s largest longitudinal study. , ...
... (Nasdaq: PRXL ), a leading global ... been named the "Best Contract,Research Organization (CRO)" by ... PAREXEL at the fourth annual Scrip Awards ceremony ... Scrip Awards are designed to,celebrate innovation and a ...
Cached Biology Technology:HUYA Bioscience Announces Agreement to Provide Schering-Plough With Drug Development Candidates From China 2HUYA Bioscience Announces Agreement to Provide Schering-Plough With Drug Development Candidates From China 3bwin and Harvard Medical School Faculty Sign 5-Year Research Cooperation Agreement 2PAREXEL Receives Best CRO Award from Scrip 2PAREXEL Receives Best CRO Award from Scrip 3PAREXEL Receives Best CRO Award from Scrip 4
(Date:9/17/2014)... as an EC-FP5 four-year project, delivering its first release ... successful participations in several EC projects, as a part ... project (EU BON), to increase the general awareness of ... the general dissemination of the Fauna Europaea results, the ... its novel e-Publishing tools to prepare data papers for ...
(Date:9/17/2014)... Copenhagen Centre for Social Evolution and Yale University offers ... weight and -length can partially predict the likelihood of ... and schizophrenia later in life. The study analyzed medical ... diagnoses for up to 30 years, and adjusted for ... published today in the Proceedings of the Royal ...
(Date:9/17/2014)... the human retinoblastoma protein gene are a leading cause ... turned to fruit fly eyes to unlock the secrets ... paper featured on the cover of the current issue ... State University researchers provide the first detailed examination of ... the human cancer gene, said Irina Pushel, MSU undergraduate ...
Breaking Biology News(10 mins):Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2Size at birth affects risk of adolescent mental health disorders 2Size at birth affects risk of adolescent mental health disorders 3Abnormal properties of cancer protein revealed in fly eyes 2
... flamingos are a curiosity of nature. Now a new discovery ... oddity that helps flamingos eat: erectile tissue. , Flamingos are ... water, they bend their necks, tilt their bills upside down ... large tongue acts like a piston, sucking water into the ...
... have interfered with the brain's ability to control an animal's ... published in the latest issue of the Proceedings of the ... is based on the identification of a gene - CPT1c ... According to the researchers, the CPT1c gene protects against weight ...
... neighborhood to a friend's house or deciding on a ... can make decisions based on incomplete information and update ... of such sophisticated decision making in the cerebral cortex, ... studied and little understood," according to Wako Yoshida and ...
Cached Biology News:Ohio University researchers discover evolutionary oddity in flamingos 2Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat 2Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat 3Where we change our mind 2
... and M.W. Turner (1997). ... step-by-step methods for the ... molecules, the use of ... analytical probes and as ...
Request Info...
LabFax: Immunochemistry...
Edited by P.J. Delves (1997) An up-to-date review of antibody-raising technologies, this volume provides researchers with immediate access to the protocols they require every day....
Biology Products: