Navigation Links
A new wide field-of-view confocal imaging system and its applications in drug discovery and pathology

de field-of-view confocal system presented in here, the reflectance imaging mode shares the same illumination and detection optics with the fluorescence mode. Neutral density filter attenuation of laser power at the detection path is used for reflectance imaging, in place of the fluorescence emission filters. In reflectance imaging, the laser light reflected/scattered from the detection volume of the specimen is collected by the laser scan lens, descanned by the scanning mirror, and detected by the same confocal detector used in fluorescence imaging (with appropriate filter changes).

2.5. Transmission Imaging

Transmission (brightfield) microscopy is the most commonly used method in the examination of histological samples, based on the absorption of the illumination light by structures in the specimen. In a conventional widefield microscope, the commonly used light sources are tungsten filament lamps with a continuum of blackbody radiation, or xenon arc lamps with a continuum between 300 and 800 nm.21 However, in the brightfield detection mode of the wide field-of-view imaging system presented in this paper, the red, green and blue (RGB) lasers are used as the illumination source to focus simultaneously through the specimen. RGB imaging is based on the color perception theory. In general, a mixture of relative amounts of red, green and blue light can present most colors to the human eye. For example, the perception of yellow (e.g., 560 nm) can be evoked by either the presence of that wavelength or the presence of comparable intensities of red (600 nm) and green (530 nm). Broadly speaking, when transilluminated as in brightfield microscopy, if a sample appears green, the red and blue lights are absorbed.

As discussed in Sect. 1.1.1, in brightfield microscopy, the tissue sections are usually stained with one or more chromophores
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31

Related biology technology :

1. Kodak in vivo imaging system: precise coregistration of molecular imaging with anatomical X-ray imaging in animals
2. Rapid hit confirmation and early hERG liability testing using the IonWorks HT system
3. High-content screening of GPCR activation with MetaXpress, AcuityXpress and the Transfluor assay system
4. Matched siRNAs and Assays: Ambion + Applied Biosystems = RNAi Success
5. Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system
6. Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system
7. Multiplex protein detection with the ECL Plex fluorescent Western blotting system using the Ettan DIGE Imager
8. Performance of Ad-A-Gene Cyclic AMP Response Element-Nitroreductase (CRE-NTR): an adenoviral vector gene delivery system
9. Amplified Fragment Length Polymorphism (AFLP) Analysis on Applied Biosystems Capillary Electrophoresis Systems
10. A technique for increasing yields in bioreactors and disposable cell-culture systems
11. An Assessment of the Eppendorf twin.tec plate performance in PCR* applications
Post Your Comments:
(Date:11/27/2014)... Ottawa, Ontario (PRWEB) November 27, 2014 ... Korean Ministry of Food and Drug Safety (MFDS) regulatory ... The system provides genetic results in less than 60 ... system is indicated as an aid for doctors to ... 2C19 genetic pathway. These include some of the world’s ...
(Date:11/26/2014)... 26, 2014 Publicis Healthcare Communications Group ... the organization has won a total of 20 awards ... LifeBrands was honored with a Silver Award and 11 ... eight Awards of Excellence. , The Annual Rx ... and promotion. The Awards provide a forum for the ...
(Date:11/26/2014)... In keeping with the holiday spirit, ... of last-minute Thanksgiving savings. The company is offering up ... product lines this holiday weekend as well as a ... and Cyber Monday are right around the corner, and ... loyal customers and those looking to explore their ancestry, ...
(Date:11/26/2014)... November 26, 2014 On January, 14, ... Baltimore and Washington D.C. science community to the UMBC ... event, sponsored by the Protein Society, will take place ... Center, Room 312. Through discussion, presentations and workshops, ... importance of proteins, their role in the industry and ...
Breaking Biology Technology:Spartan Bioscience Receives Korean Regulatory Approval for First Rapid DNA Test of Mutations Affecting Metabolism of Common Drugs 2Spartan Bioscience Receives Korean Regulatory Approval for First Rapid DNA Test of Mutations Affecting Metabolism of Common Drugs 3Publicis Healthcare Wins 20 Rx Club Awards 2Publicis Healthcare Wins 20 Rx Club Awards 3DNA Spectrum Offers Last Minute Thanksgiving Coupons 2DNA Spectrum Offers Last Minute Thanksgiving Coupons 3
... Mass., March 19 Biopure,Corporation (Nasdaq: ... Kingdom,s,Medicines and Healthcare products Regulatory Agency (MHRA) ... manufacturing facility. The,inspection report contained no "Critical" ... manufacturing practices. The MHRA report identified,shortcomings characterized ...
... 19 AdvanDx announced it received,Frost & ... Award in the,field of rapid in-vitro molecular ... on AdvanDx,s easy-to-use, molecular-based,PNA FISH(TM) diagnostics to ... days. The rapid PNA FISH results enable ...
... MacroChem,Corporation (OTC Bulletin Board: MACM) today announced ... of Chief Financial Officer, effective,immediately. Mr. Luci has ... Development since joining the Company in December,2007., ... Inc. prior to its,successful merger transaction with Genzyme ...
Cached Biology Technology:Biopure Completes U.K. Regulatory Agency Inspection 2AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 2AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 3AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 4MacroChem Appoints David P. Luci as New CFO 2MacroChem Appoints David P. Luci as New CFO 3
(Date:11/4/2014)... 2014 – University of Utah engineers developed the first ... fuel produce electricity without needing to ignite the fuel. ... portable electronics, off-grid power and sensors. , A study ... American Chemical Society journal ACS Catalysis . , ... reaction between a fuel and an oxygen-rich source such ...
(Date:11/4/2014)... Think about the way our bodies are assembled during ... that they are supposed to become a nerve or ... the correct place and alignment? Researchers at the University ... In a new study, UM researchers describe the signaling ... neighbors, at the head-trunk region. Their discovery may have ...
(Date:11/4/2014)... A majority of Madagascar,s 101 species of lemurs are ... for the rainforests they call home. A new study ... can have on rainforest tree populations, which raises concerns ... the region,s rich biodiversity. , A large proportion of ... Lemurs in turn disperse the seeds of their ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2The inside story: How the brain and skull stay together 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... engineer has been awarded a $394,300 grant from the ... flow in the new facilities of the 150-mile Integrated ... of civil engineering, will investigate the best methods and ... effort to eliminate biological growths in the new pump ...
... awarded $12.7 million to match nine academic research ... to explore new treatments for patients in eight ... and schizophrenia. The collaborative pilot initiative, called Discovering ... by the National Center for Advancing Translational Sciences ...
... 10% of breast and ovarian cancers are familial in ... attributable to inherited mutations from the parents in genes ... mutations, PARP inhibitors, which are currently in clinical trials, ... option for personalised cancer treatment, an alternative to standard ...
Cached Biology News:UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2NIH to fund collaborations with industry to identify new uses for existing compounds 2NIH to fund collaborations with industry to identify new uses for existing compounds 3NIH to fund collaborations with industry to identify new uses for existing compounds 4An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer 2
Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP). [Source:Uniprot/SWISSPROT;Acc:P08697] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Mouse polyclonal antibody raised against a partial recombinant CSRP3. NCBI Entrez Gene ID = 8048...
Mouse monoclonal antibody raised against a partial recombinant EOMES. NCBI Entrez Gene ID = EOMES...
...
Biology Products: