Navigation Links
A new wide field-of-view confocal imaging system and its applications in drug discovery and pathology

confocal imaging in reflection and fluorescence modes. In addition, an RGB brightfield (non-confocal) imaging mode is also available.

2.1. Laser Scan Lens

One of the most important and expensive components of the wide field-of-view imaging system is the custom- designed laser scan lens. Currently, two proprietary scan lenses have been designed and built, with specimen magnification, excitation NA and fluorescence collection NA of 10X/0.20/0.35 and 40X/0.50/0.50, respectively. They have a working distance, lateral and axial resolution of 6mm/2μm/25μm and 3mm/0.5μm/4μm, respectively.

The laser scan lenses are color-corrected, infinity-corrected, telecentric and F*Theta (or F *Θ) lenses with the entrance pupil outside the lens system. A infinity-corrected lens allows greater flexibility in the imaging system design. Various dichroic beamsplitters and other accessories can be readily inserted into the collimated beam. With the entrance pupil located outside the scan lens, it is possible to use a scanning mirror of the smallest size to fill the entrance pupil with the excitation beam. On the contrary, the entrance pupil of a standard microscope objective is located inside the lens system. If used for scanning imaging, it is necessary to use relay optics to place the pivot point of the scanning beam at the entrance pupil position.50

The laser scan lens has telecentric and F*Theta properties, which are essential for optimal imaging flat specimens and performing linear scan. In a telecentric scan lens, the chief ray always emerges parallel to the optical axis during the scan, i.e., the chief ray of the converging cone of light always is perpendicular to the specimen plane/focal plane. Telecentricy guarantees that the optical measurement is independent of the imaging position acros
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31

Related biology technology :

1. Kodak in vivo imaging system: precise coregistration of molecular imaging with anatomical X-ray imaging in animals
2. Rapid hit confirmation and early hERG liability testing using the IonWorks HT system
3. High-content screening of GPCR activation with MetaXpress, AcuityXpress and the Transfluor assay system
4. Matched siRNAs and Assays: Ambion + Applied Biosystems = RNAi Success
5. Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system
6. Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system
7. Multiplex protein detection with the ECL Plex fluorescent Western blotting system using the Ettan DIGE Imager
8. Performance of Ad-A-Gene Cyclic AMP Response Element-Nitroreductase (CRE-NTR): an adenoviral vector gene delivery system
9. Amplified Fragment Length Polymorphism (AFLP) Analysis on Applied Biosystems Capillary Electrophoresis Systems
10. A technique for increasing yields in bioreactors and disposable cell-culture systems
11. An Assessment of the Eppendorf twin.tec plate performance in PCR* applications
Post Your Comments:
(Date:8/28/2015)... -- According to a new market research ... Thawing Equipment, Alarms), by Biospecimen (Human Tissue, Stem Cells, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... Million by 2020 from USD 2,150.48 Million in 2015, ... 2020. Browse 74 Tables and 95 ...
(Date:8/28/2015)... ... ... of FireflySci Inc. (FFS) in early 2015, the company continues to shake up the cuvette ... in a lab coat and Large Marge have been posted on the company’s Facebook page ... is proud to be the only cuvette manufacturer is the world that has an online ...
(Date:8/27/2015)... -- The National Necrotizing Fasciitis Foundation (NNFF) ... doctors at Vanderbilt University Hospital in Nashville, ... Dr. John Crew , director of the ... in Daly City, CA. ... by Dr. Crew, that had previously saved the lives ...
(Date:8/27/2015)... ... 27, 2015 , ... Inc. Magazine released its annual list of the 5,000 ... in growth for the three years through 2014. Being named to the Inc. 5000 ... in the country. , “We are thrilled to make the Inc. 5000 list ...
Breaking Biology Technology:Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3
... eye uses tiny muscles to focus on different distances. ... some sensors do not require these external controls. , ... Engineering are investigating a liquid lens design that ... in a variety of commercial applications, including medical diagnostic ...
... Wis. - Although the third major storm ... Chris, fizzled into a low-pressure system recently, apprehensions ... circulate across the country. , ,A Wisconsin telecommunications ... that apprehension away. , ,To address concerns of ...
... Inc. , a supplier of DNA microarrays for genome ... experience managing large entrepreneurial growth companies. , ,David Snyder ... raising, finance, and general management in a range of ... ,In a statement released by NimbleGen, President and CEO ...
Cached Biology Technology:"Smart" lenses hold commercial potential 2Wisconsin firm leads testing of alerts by cell phone 2Wisconsin firm leads testing of alerts by cell phone 3NimbleGen names CFO with capital-raising past 2
(Date:8/12/2015)... MINNETONKA, Minn. , Aug. 12, 2015   ... that supports the entire spectrum of clinical research, is ... ™ , the company,s comprehensive SaaS-based eClinical technology platform, ... growth during the first two quarters of 2015.   ... and second largest quarters measured by contract value sold ...
(Date:8/10/2015)... and TELTOW, Germany , August ... (SMI), a world leader in Eye Tracking Technology ... of its OEM Eye Tracking Platform for integration into ... Platform contains reference designs for seamless integration of eye ... virtual reality HMDs and augmented reality smart glasses. Omnivision,s ...
(Date:8/5/2015)... 2015 According to a new ... Software, Services, Vertical (BFSI, Airport, IT & Telecom, Utilities, ... Forecast to 2020", published by MarketsandMarkets, defines and segments ... various segments. The global PIAM Market is estimated to ... by 2019, at a CAGR of 14.9 % from ...
Breaking Biology News(10 mins):MedNet Solutions Experiences Explosive Corporate Growth 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4
... team at Stevens Institute of Technology is working to ... thoracic surgeries. Five undergraduate Biomedical Engineering students have invented ... catheter design and introduces a potentially profitable new product ... of the Stevens Innovative Fluid Extraction System (SIFES) Senior ...
... Asia for its medicinal benefits has been found to ... development in mice during early trials, new Queensland University ... (PSP), which is extracted from the ,turkey tail, mushroom, ... suppress tumour formation in mice, an article written by ...
... Boston, MA The physical forces that guide how cells ... a coordinated fashion inside the living body are poorly understood. ... the Institute for Bioengineering of Catalonia (IBEC) have, for the ... collective cellular migration. Their surprising conclusion is that the cells ...
Cached Biology News:Stevens thoracic catheter senior design team takes 1st place at regional ISPE competition 2Stevens thoracic catheter senior design team takes 1st place at regional ISPE competition 3Mushroom compound suppresses prostate tumors 2The dance of the cells: A minuet or a mosh? 2The dance of the cells: A minuet or a mosh? 3
Anti-human C5/C5b, Clone 568, Monoclonal Antibody...
Proline-serine-threonine phosphatase-interacting protein 2...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Anti-ACTH Immunogen: Porcine ACTH conjugated to BSA. Available Date: 38566...
Biology Products: