PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clini...(at all the riskthat Soliris will not gen...)

Date:8/20/2007

at all, the risk that Soliris will not generate interest among physicians, the risk that estimates regarding the number of PNH patients are inaccurate, the risk that pending litigation may be resolved adversely, and a variety of other risks set forth from time to time in Alexion's filings with the Securities and Exchange Commission, including but not limited to the risks discussed in Alexion's Quarterly Report on Form 10-Q for the period ended June 30, 2007 and in our other filings with the Securities and Exchange Commission. Alexion does not intend to update any of these forward-looking statements to reflect events or circumstances after the date hereof, except when a duty arises under law.

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(3) Socie G, Mary J Yves, de Gramont A, et al. Paroxysmal nocturnal

haemoglobinuria: long-term follow-up and prognostic factors. Lancet

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(4) Hillmen P. Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history

of paroxysmal nocturnal hemoglobinuria. N Engl J Med 1995;

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(6) Araten DJ, Thaler HT, Luzzatto L. High incidence of thrombosis in

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SOURCE Alexion Pharmaceuticals, Inc. Copyright©2007 PR Newswire.

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