Navigation Links
Merrimack to Present Pre-Clinical Data on MM-121 and MM-111 at the 101st Annual Meeting of American Association for Cancer Research (AACR)
Date:4/17/2010

MM-121 studies in breast cancer models and xenograft response prediction. MM-111 breast cancer study in combination with trastuzumab.

Cambridge, MA (PRWEB) April 17, 2010 -- Merrimack Pharmaceuticals, Inc. announced today that it will present pre-clinical data on MM-121 and MM-111, the two lead candidates in the company’s pipeline of five novel cancer antibodies, at the 101st Annual Meeting of the American Association for Cancer Research (AACR) being held April 17 – 21, 2010, in Washington, D.C.

MM-121
Two posters will show pre-clinical data on MM-121, a monoclonal antibody designed to block signaling of the ErbB3 receptor. The ErbB receptor family has been known for years to have an impact on cancer signaling. Merrimack gained insight into the critical role of the ErbB3 receptor in cancer biology through the use of their Network Biology platform that led to the novel design of MM-121.

Poster 1806 shows pre-clinical data on MM-121’s efficacy as a single agent, and in combination with tamoxifen and paclitaxel, in ER+ and triple negative breast cancer studies.

Title: Efficacy of MM-121 in ER+ and triple negative breast cancer studies
Poster Session: Clinical Research 7
Number: 1806
Date/Time: Monday April 19, 2010 9:00 AM - 12:00 PM
Location: Exhibit Hall A-C, Poster Section 32 Permanent Abstract


MM-121
Poster 3756 shows pre-clinical data on efforts to derive a predictive biomarker signature that identifies tumors responsive to MM-121.

Title: Prediction of xenograft response to MM-121, an anti-ErbB3 inhibitor, using computational modeling and measurements of five biomarkers
Poster Session: Clinical Research 13
Number: 3756
Date/Time: Tuesday April 20, 2010 9:00 AM - 12:00 PM
Location: Exhibit Hall A-C, Poster Section 33


MM-111
MM-111 is a bispec
'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved

0

GOOD

Page: 1 2 3

Related biology technology :

1. Clet Niyikiza, Merrimack's Executive Vice President of Development, to Present at BioVisionAlexandria 2010
2. Merrimack Pharmaceuticals Promotes William Sullivan to Vice President of Finance
3. Merrimack Pharmaceuticals Recognized for Innovative Talent Management in HR Executive Magazine's ‘Best HR Ideas for 2010' Issue
4. Merrimack Pharmaceuticals Initiates Enrollment in Phase 1/2 Combination Study of MM-121 and Tarceva in Patients with Non-Small Cell Lung Cancer
5. Merrimack Pharmaceuticals Acquires Hermes Biosciences, Inc.
6. Merrimack Pharmaceuticals Names Clet Niyikiza, Ph.D. Senior Vice President, Development
7. Merrimack Pharmaceuticals Promotes Ulrik B. Nielsen, Ph.D. to Chief Scientific Officer and Edward J. Stewart to Senior Vice President of Business Development
8. Merrimack Pharmaceuticals Initiates Enrollment in a Phase 1 Study of MM-121, an ErbB3 Antagonist
9. Merrimack Pharmaceuticals Raises $60 Million in Private Financing
10. Merrimack Pharmaceuticals Announces the Addition of Robert Gay to its Board of Directors
11. Zimmer Holdings to Present at Barclays Capital 2010 Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013 Patheon Inc ., a ... the global pharmaceutical industry, will host a complimentary webinar ... Testing” on Tuesday, June 4, 2013 at 11 a.m. ... required to comply with regulations for cleaning validation. ... scientific underpinning and little evaluation of risk. Some ...
(Date:5/23/2013)...  Rahal Letterman Lanigan Racing (RLL) and StemCyte, Inc., ... banking and therapeutics, announced today that StemCyte has become ... Indy car driven by James Jakes ... IndyCar 2013 season.   StemCyte, Inc. and Rahal ... of umbilical cord blood banking and its educational initiative ...
(Date:5/23/2013)... Auburn, MA (PRWEB) May 23, 2013 ... one inch wide and provide 15 mm travel ... nanometers. The small dimensions make these new ... in confined spaces. A vacuum rated version is ... Datasheet:, Drawings, specifications and datasheets can be found ...
(Date:5/23/2013)... Calif. , May 23, 2013  Saddleback Memorial ... recently became the first hospital on the West ... technology. This new surgical option provides women with a ... Marc Winter , M.D., a ... and surgeon and medical director of minimally invasive surgery ...
Breaking Biology Technology:Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Precision Positioning System Uses Miniaturezed Piezo Linear Motor: LPS-24 Linear Stage by PI 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 3
... project management isnt always so common , ,Despite ... are still late, over budget and without the results they ... project is over we rationalize that there wasn't enough time ... team were ridiculous. But when you research and analyze the ...
... Standard Networks announced Tuesday its MOVEit family of ... of capabilities to help guarantee server file delivery. The ... confirmation. , ,MOVEit DMZ servers and MOVEit clients now ... a file is successfully delivered. Files that fail at ...
... College of Engineering, Dean Paul Peercy and his faculty ... includes what it takes to be competitive in todays ... System and the Wisconsin Technical College System, a joint ... with four-year baccalaureate degrees and in what disciplines ...
Cached Biology Technology:Part 3 Project performance Get on the path to continuous improvement 2Part 3 Project performance Get on the path to continuous improvement 3Wisconsin must produce more science-savvy students to remain competitive 2Wisconsin must produce more science-savvy students to remain competitive 3
(Date:5/23/2013)... year, carrying more than 284 million tons of cargo, transit ... in toll fees for the Panama Canal Authority. Each time ... water are used from Gatun Lake, which is also a ... the isthmus. , However, the advent of very large ... ships at sea, has demanded change. The Panama Canal is ...
(Date:5/23/2013)... DNA around nucleosomes in the cell nucleus makes ... Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism ... from nucleosomes for transcription. , In higher organisms ... nucleus, wrapped around disk-shaped particles called nucleosomes, each ... proteins and accommodating two loops of DNA. Packed ...
(Date:5/23/2013)... A new report from the Institute of Medicine says ... at least 60 minutes of vigorous or moderate intensity ... half of American youth meet current evidence-based guidelines of ... physical activity daily, according to the report, which was ... for nearly half of their waking hours, the committee ...
Breaking Biology News(10 mins):Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3Biochemistry: Unspooling DNA from nucleosomal disks 2Schools should provide students with daily physical activity, IOM recommends 2
... Calif. The University of California, Riverside has signed ... , a South African company, to market ,GEM, an ... According to the agreement signed last month, Westfalia will ... world. Currently, in the United States, the Californiabased ...
... "Metabolism is Not Boring!" asserts the introduction to a ... 3 December 2010). On the contrary, the ways in ... the building blocks of macromolecules are crucial for life. ... the single-celled to multicellular organisms. This gives special importance ...
... clinical trials prove successful, a new discovery published in ... represent a major scientific leap toward human tissue regeneration ... scientists provide evidence to support a major paradigm shift ... added to a graft before implantation are the building ...
Cached Biology News:UC Riverside licenses leading South African company to market 'GEM' avocados 2UC Riverside licenses leading South African company to market 'GEM' avocados 3Yale scientists discover new method for engineering human tissue regeneration 2
... GenoStat Inducible Expression System provides tightly regulated ... cells and is capable of repeated on/off ... mediated by the highly specific interaction between ... nuclear receptor complex. Gene expression levels are ...
... is extensively scrutinized, including negative ... All horses are of U.S. ... are controlled and documented to ... Pricing: $12/unit for ...
... sets added in Dec 2005 , ... , Detection from as little as 25 ... primers available for hundreds of mammalian miRNAs ... RT-PCR , Ideal for validating expression ...
jub, ajuba homolog (Xenopus laevis)...
Biology Products: