Navigation Links
Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease
Date:6/8/2009

Researchers at the National Institute on Aging, University College London, and Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson's disease (PD) patients - but at very low frequency in the general population. The signature is found in the LRRK2 gene located on chromosome 12. The work was led by Elizabeth Corder, PhD, Scientific director at Matrix Genomics, Inc.

(PRWEB) June 5, 2009 -- Researchers at the National Institute on Aging, University College London, and Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson's disease (PD) patients - but at very low frequency in the general population. The signature is found in the LRRK2 gene located on chromosome 12. The work was led by Elizabeth H. Corder, PhD, Scientific Director at Matrix Genomics.

Parkinson's disease is the second most common neurodegenerative disorder in the Western world, and a major cause of disability and distress among older Americans. Family studies have long indicated that Parkinson's is a genetic disorder when certain mutations are inherited. However, specific genetic factors relevant to the general population have been elusive.

The PD gene is called leucine risk repeat kinase 2 (LRRK2), which encodes a protein called dardarin, derived from the Basque word dardara, meaning tremor. Mutations in LRRK2 are a common cause of familial Parkinson's disease.

'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. NeoMatrix Announces Additional Funding for Breakthrough Breast Cancer Screening Test
2. BioNanomatrix Announces Issuance of Key Nanofluidics Patent Enabling Single Molecule Whole Genome Analysis
3. BioNanomatrix Receives New NCI Grant to Support Development of Chip-Based Nanofluidics Systems for Cell Fractionation
4. BioNanomatrix and Complete Genomics Receive $8.8 Million NIST-ATP Award to Develop Sequencing Platform for $100 Genome
5. TEI Biosciences Launches SurgiMend(TM) Collagen Matrix for Soft Tissue Reconstruction
6. Collagen Matrix, Inc. Launches OssiMend(TM) Bone Graft Matrix for Orthopedic and Spine Applications
7. Biosensors Receives CE Mark Approval for Its BioMatrix(R) Drug-Eluting Coronary Stent System
8. CombiMatrix and Clarient Collaborate to Market, Sell Novel Genomics-Based Test for Chronic Lymphotic Leukemia (CLL)
9. Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc.
10. Engineers make first active matrix display using nanowires
11. BioNanomatrix Named Best Management Team at the 2008 Ben Franklin Emerging Business Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... researchers have developed a battery that takes advantage of ... produce electricity. Anywhere freshwater enters the sea, such ... for a power plant using such a battery, said ... who led the research team. The theoretical limiting ...
... Marshall Edwards, Inc.(Nasdaq: MSHL ), an ... therapeutics targeting cancer metabolism, announced today that an abstract ... for a late-breaking poster presentation at the American Association ... 4, 2011 at 1:00 p.m. EDT at the Orange ...
... March 29, 2011 Soligenix, Inc. (OTC Bulletin Board: ... late-stage biopharmaceutical company, announced today its financial results for ... Soligenix,s revenues for the year ended December 31, 2010 ... year, representing a decrease of $868,409, or 31%.  During ...
Cached Biology Technology:Stanford researchers use river water and salty ocean water to generate electricity 2Stanford researchers use river water and salty ocean water to generate electricity 3Marshall Edwards to Report new Data on Mitochondrial Inhibitor Program at American Association for Cancer Research Annual Meeting 2Marshall Edwards to Report new Data on Mitochondrial Inhibitor Program at American Association for Cancer Research Annual Meeting 3Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 2Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 3Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 4Soligenix Reports Year-End 2010 Financial Results and Highlights Recent Accomplishments 5
(Date:4/15/2014)... April 15, 2014, Irvine, Calif. UC Irvine neurobiologists ... positive results when transplanted into the brains of mice ... pre-clinical trial is published in the journal Stem ... been shown to work in two different mouse models. ... forms of dementia, is associated with accumulation of the ...
(Date:4/15/2014)... know as early as 2020 how high sea levels ... team of researchers including Florida International University scientist Rene ... Science Foundation,s (NSF) Florida Coastal Everglades Long-Term Ecological Research ... in ecosystems from coral reefs to deserts, mountains to ... sea level rise is one of the most certain ...
(Date:4/15/2014)... Biologists at UC San Diego have succeeded in ... hormone responsible for growth and resistance to drought. ... studies to determine how the hormone helps plants ... by the continuing increase in the atmosphere,s carbon ... achievement appears in the April 15 issue of ...
Breaking Biology News(10 mins):UCI study finds modified stem cells offer potential pathway to treat Alzheimer's disease 2Long-term predictions for Miami sea level rise could be available relatively soon 2Biologists develop nanosensors to visualize movements and distribution of plant hormone 2
... --- Northwestern University has received a three-year, $1.6 million ... science research focused on understanding the chemical and biological ... The egg and sperm unite at the time of ... This single cell then divides many times, ultimately forming ...
... Ikaria Holdings, Inc., a fully,integrated critical care ... Drug Administration (FDA) has granted orphan drug designation,for ... of the incidence and,severity of delayed graft function ... Rosskamp, M.D., Executive Vice President of Research and,Development ...
... eventually led Joe Williams to hang from the limbs ... northeastern Australia. The things Williams, a University of ... amazing diversity in the world,s flowering plants, a question ... Darwin to today. Williams, findings, published online this ...
Cached Biology News:W.M. Keck Foundation grant funds reproductive science research 2W.M. Keck Foundation grant funds reproductive science research 3Ikaria(R) Receives FDA Orphan Drug Designation for Inhaled Carbon Monoxide for Delayed Graft Function in Solid Organ Transplants 2UT Knoxville professor finds unexpected key to flowering plants' diversity 2