Navigation Links
Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease
Date:6/8/2009

Researchers at the National Institute on Aging, University College London, and Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson's disease (PD) patients - but at very low frequency in the general population. The signature is found in the LRRK2 gene located on chromosome 12. The work was led by Elizabeth Corder, PhD, Scientific director at Matrix Genomics, Inc.

(PRWEB) June 5, 2009 -- Researchers at the National Institute on Aging, University College London, and Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson's disease (PD) patients - but at very low frequency in the general population. The signature is found in the LRRK2 gene located on chromosome 12. The work was led by Elizabeth H. Corder, PhD, Scientific Director at Matrix Genomics.

Parkinson's disease is the second most common neurodegenerative disorder in the Western world, and a major cause of disability and distress among older Americans. Family studies have long indicated that Parkinson's is a genetic disorder when certain mutations are inherited. However, specific genetic factors relevant to the general population have been elusive.

The PD gene is called leucine risk repeat kinase 2 (LRRK2), which encodes a protein called dardarin, derived from the Basque word dardara, meaning tremor. Mutations in LRRK2 are a common cause of familial Parkinson's disease.

'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. NeoMatrix Announces Additional Funding for Breakthrough Breast Cancer Screening Test
2. BioNanomatrix Announces Issuance of Key Nanofluidics Patent Enabling Single Molecule Whole Genome Analysis
3. BioNanomatrix Receives New NCI Grant to Support Development of Chip-Based Nanofluidics Systems for Cell Fractionation
4. BioNanomatrix and Complete Genomics Receive $8.8 Million NIST-ATP Award to Develop Sequencing Platform for $100 Genome
5. TEI Biosciences Launches SurgiMend(TM) Collagen Matrix for Soft Tissue Reconstruction
6. Collagen Matrix, Inc. Launches OssiMend(TM) Bone Graft Matrix for Orthopedic and Spine Applications
7. Biosensors Receives CE Mark Approval for Its BioMatrix(R) Drug-Eluting Coronary Stent System
8. CombiMatrix and Clarient Collaborate to Market, Sell Novel Genomics-Based Test for Chronic Lymphotic Leukemia (CLL)
9. Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc.
10. Engineers make first active matrix display using nanowires
11. BioNanomatrix Named Best Management Team at the 2008 Ben Franklin Emerging Business Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... -- This report analyzes the worldwide markets for Bioinformatics in ... Biocontent. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2013 ... these markets. Market data and analytics are derived from primary ...
(Date:9/16/2014)... University scientists who created a deicing film for radar ... a transparent coating for glass. , The new ... could keep glass surfaces from windshields to skyscrapers free ... radio frequencies (RF). , The technology was introduced ... Applied Materials and Interfaces . , The material ...
(Date:9/16/2014)... , Sept. 16, 2014  The Council ... entrepreneurial support organization in the country, today released ... Report . It showed that ... North Carolina startups in the technology, ... more global investment from a variety of sources. Significant ...
(Date:9/16/2014)... BARBARA, Calif. , Sept. 16, 2014 /PRNewswire-iReach/ ... Strength index (BMSi) test identifies patients with bone ... cannot.  Over 160 million people worldwide are at ... detected by today,s standard bone strength test, the ... the 2014 American Society for Bone and Mineral ...
Breaking Biology Technology:Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23Nanoribbon film keeps glass ice-free 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 3CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 4ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 2ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 3
... of PCR reactions with Herculase enhanced DNA,polymerase ... ,Stratagene , Stratagene recently released Herculase ... that provides,superior performance in both routine and demanding ... exhibits greater fidelity than,commercial DNA polymerase blends, in ...
... ,Single-tube amplification method for high-throughput screening of HSV ... Peter Pingerelli ,Melanie Palmer Dwight DuBois ,Stratagene , ... , ff ,a single-tube ... Because,it is performed in a closed-tube system and requires ...
... developed for,highfidelity PCR , , Kirk B. Nielson ... Barbara McGowan * Holly Hogrefe ,Stratagene Cloning Systems, Inc. ... Precision PCR system,* to an expanding line of PCR ... mixture of Taq2000 and Pfu DNA polymerases and a ...
Cached Biology Technology:Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 2Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 3Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 4Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 5Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 6Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 7Unique Enhanced DNA Polymerase Delivers High Fidelity and Great PCR,Performance 8HSVision Molecular Beacon Detection Module Rapidly Detects Herpes Simplex,Virus DNA 2HSVision Molecular Beacon Detection Module Rapidly Detects Herpes Simplex,Virus DNA 3HSVision Molecular Beacon Detection Module Rapidly Detects Herpes Simplex,Virus DNA 4High-Fidelity PCR with a Novel Polymerase Mixture 2High-Fidelity PCR with a Novel Polymerase Mixture 3High-Fidelity PCR with a Novel Polymerase Mixture 4High-Fidelity PCR with a Novel Polymerase Mixture 5High-Fidelity PCR with a Novel Polymerase Mixture 6High-Fidelity PCR with a Novel Polymerase Mixture 7High-Fidelity PCR with a Novel Polymerase Mixture 8High-Fidelity PCR with a Novel Polymerase Mixture 9High-Fidelity PCR with a Novel Polymerase Mixture 10High-Fidelity PCR with a Novel Polymerase Mixture 11
(Date:9/16/2014)... Three years after the Hesperides vessel returned to Spain ... researchers have an increasingly clear picture of how the ... Specifically, the input of pollutants from the atmosphere is ... the most remote areas of the planet, and it ... findings are presented this week in CSIC Residence for ...
(Date:9/16/2014)... a peacock show its extravagant, colorful tail feathers in ... have used a special camera developed by an engineer ... female northern swordtail fish choose their mates based on ... of Texas at Austin used a bioinspired polarization camera ... science & engineering at Washington University, to make the ...
(Date:9/16/2014)... the salmon-rich waters of Southeast Alaska to the white ... lobster, lumber and tourist towns, coastal residents around the ... environments divide along political lines. That,s a primary finding ... sociologists published this month in the journal Society ... of environment-related differences from place to place to place. ...
Breaking Biology News(10 mins):The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 2The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 3Camera developed at WUSTL sheds light on mate choice of swordtail fish 2Politics divide coastal residents' views of environment, UNH research finds 2Politics divide coastal residents' views of environment, UNH research finds 3
... MADISON A discovery at the University of Wisconsin-Madison ... create a "hydrogen economy" that would use this abundant ... hydrogen is the ultimate non-carbon, non-polluting fuel for storing ... for energy, hydrogen produces water but no carbon dioxide. ...
... the bacteria that form the base of the ocean,s ... a new study. In climate change, as in ... dioxide levels and temperature rise globally, scientists increasingly want ... perish in the environment of tomorrow. The answer ...
... Brookhaven National Laboratory have identified two promising candidates for ... of ailments ranging from colds to gastrointestinal disorders to ... , a journal of the Federation of European Biochemical ... compounds to determine which might block the effects of ...
Cached Biology News:New catalyst could cut cost of making hydrogen fuel 2Greenhouse gas likely altering ocean foodchain 2Scientists identify promising antiviral compounds 2Scientists identify promising antiviral compounds 3
Recombinant Mouse Wnt-3a...
... There are at least 20 structurally ... of the TGF-beta superfamily. BMPs were originally ... bone formation. They are also involved in ... organs. BMPs regulate the growth, differentiation, chemotaxis ...
RABBIT ANTI HUMAN TRRAP (CT) Immunogen: Recombinant C-terminal kinase-related domain of human TRRAP....
RABBIT ANTI HUMAN CHYMOTRYPSIN...
Biology Products: