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Lung Rx and ImmuneWorks Announce Collaboration in Idiopathic Pulmonary Fibrosis and Primary Graft Dysfunction
Date:2/10/2010

SILVER SPRING, Md., and INDIANAPOLIS, Feb. 10 /PRNewswire-FirstCall/ -- Lung Rx, LLC, a wholly-owned subsidiary of United Therapeutics Corporation (Nasdaq: UTHR), announced today that it has entered into a Development Agreement with ImmuneWorks, Inc. to pursue development of ImmuneWorks' lead compound, IW001, a purified bovine Type V Collagen oral solution for the treatment of Idiopathic Pulmonary Fibrosis (IPF) and Primary Graft Dysfunction (PGD) in patients receiving lung transplant.  The parties expect to commence human clinical testing in 2010.  In November 2009, the U.S. Food and Drug Administration granted orphan drug exclusivity to IW001.

"We are delighted to form this alliance with ImmuneWorks in these areas of high unmet medical need," said Lung Rx President and CEO Martine Rothblatt, Ph.D.  "This development program further solidifies our commitment to clinical research in diseases with few, if any, approved therapeutic options."

In addition to funding the development program, Lung Rx has been granted an option to acquire all of the issued and outstanding capital stock of ImmuneWorks.  Financial terms of the transaction were not disclosed.

"We are extremely pleased to align with Lung Rx and United Therapeutics, companies that share our commitment to bringing novel treatments to patients suffering from incurable lung diseases such as idiopathic pulmonary fibrosis and those undergoing lung transplantation," said Wade A. Lange, President & CEO of ImmuneWorks.  "We strongly believe that the coupling of United Therapeutics' track record of innovation and our novel therapeutic approa
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SOURCE United Therapeutics Corporation
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