Navigation Links
Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting
Date:7/14/2009

LAGUNA NIGUEL, Calif., July 14 /PRNewswire/ -- Inspiration Biopharmaceuticals today announced the presentation of positive preclinical safety, toxicology and preliminary pharmacokinetic data on its lead product, IB1001, a novel recombinant Factor IX product to treat patients with hemophilia B. The data were highlighted in an oral presentation yesterday at the XXII Congress of the International Society on Thrombosis and Haemostasis (ISTH) in Boston, Mass. IB1001 has completed preclinical testing and is currently being evaluated in a Phase 1/2-3 clinical study.

In the study, the safety, toxicology and pharmacokinetics of IB1001 were evaluated in animal models and compared to commercially available Factor IX products. Results showed that IB1001 has an excellent safety profile in animal models and a similar pharmacokinetic profile when compared to currently available Factor IX products.

"These results and the progress that we have made in advancing our protein manufacturing technology have facilitated the advancement of IB1001 into a Phase 1/2-3 clinical program," said Michael Griffith, Ph.D., President and CEO, Inspiration Biopharmaceuticals. "Our ultimate goal is to increase accessibility to prophylactic treatment and improve the quality of life for people suffering from hemophilia around the world. We expect to move IB1001 into a pivotal trial and look forward to updating you on all developments related to this program."

About IB1001

IB1001 is an intravenous recombinant Factor IX product for the acute and preventative treatment of the bleeding disorder associated with hemophilia B. IB1001 is produced with Inspiration's proprietary recombinant protein manufacturing technology, which significantly increases cell-line productivity.

About Hemophilia

Hemophilia is a lifelong, inherited bleeding disorder cause
'/>"/>

SOURCE Inspiration Biopharmaceuticals
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related biology technology :

1. Gyros Raises SEK 80 Million to Accelerate the Commercialization of its Gyrolab(R) Systems for the Cost-Efficient Development of Biopharmaceuticals
2. Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients
3. Keryx Biopharmaceuticals Announces Appointment of Ron Bentsur as Chief Executive Officer
4. Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology
5. Keryx Biopharmaceuticals, Inc. to Hold Conference Call on First Quarter 2009 Financial Results on Thursday, May 14, 2009 at 8:30am EDT
6. Keryx Biopharmaceuticals, Inc. Announces Michael P. Tarnok as Interim Chairman and Chief Executive Officer
7. Keryx Biopharmaceuticals Presents Encouraging Preclinical Data at Annual Meeting of the American Association of Cancer Research
8. XTL Biopharmaceuticals Ltd. Receives Notification of Delisting Determination by NASDAQ Listing Qualifications Panel
9. The Need for Safe and Affordable Biopharmaceuticals Drives the Development of the European Biosimilars Market, Says Frost & Sullivan
10. Keryx Biopharmaceuticals, Inc. Announces Fourth Quarter and Year-End 2008 Financial Results
11. Keryx Biopharmaceuticals, Inc. to Hold Conference Call on Fourth Quarter and Year-End 2008 Financial Results on Friday, March 13, 2009 at 8:30am EDT

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)... Health care employment gre... the only one to show consistent growth during the...spitals remain in trouble, and health systems are ...rsonnel, instead of just administrators. , ...lth care employment continued growing in October d...
(Date:11/24/2009)..., SEATTLE,Nov.24/PRNewswire/--BlueMarbleEnergyCo...evelopmentAuthority(OPDA)wererecentlyawarded$2mill...ionBoard(CERB)inaprivate/publicpartnershiptoconstr...nLincolnCounty,WA. ,, "Thisinvestmentwillsignif...over70greenjobstoLincolnCounty,"saidBlueMarbleEner...
(Date:11/24/2009)..., SANDIEGO,Nov.24,2009/PRNewswire-FirstCall/--Ar...odaythatthecompanyisscheduledtopresentatthePiperJa...9at11:30a.m.EasternTime(8:30a.m.PacificTime)attheN...esident andChiefExecutiveOfficer,isscheduledtoprov...lopmentanddiscoveryprograms. ,, Aliveaudiowebca...
(Date:11/24/2009)..., SEATTLE,Nov.24/PRNewswire-FirstCall/--CellTher...lpresentatthe21stAnnualPiperJaffrayHealthCareConfe...eNewYorkPalaceHotel. ,, CTIwillpresentonTuesday...).AliveaudiowebcastofCTI,spresentationwillbeavaila...ilableforreplayafterwards. , ,PiperJaffrayHealthC...
Breaking Biology Technology:The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 2The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 3The MedZilla Report for October 2009 - Health Care Employment Grows Again in October Even As Clinics, Specialty Centers Close 4Blue Marble Energy, OPDA Awarded $2M by WA's Community Economic Revitalization Board 2Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 2
...hibition and Anti-Tumor Activity , , SOUTH S...ay announced results from a series of in vitro a...47, the company,s oral proteasome inhibitor. Thes...reclinical Pharmacology and In Vitro Characterizat...some" (Abstract # 3671) at the 50th Annual Meetin...
...d,(Nasdaq: ARAY ), a global leader in the field ...fe(R) Robotic Radiosurgery Systems now have been i...hen Hospital Corporation of America,(HCA), a leadi...nife System in,collaboration with consultant clini...n. HCA,s addition of this CyberKnife System marks...
...today aims to reduce nutrient and sediment movemen... Mississippi River. Monsanto is partnering with,mu...re working with farmers to,help reduce runoff from... The Nature Conservancy, the Iowa Soybean Ass...oratively with farmers to remove nutrients and sed...
Other Biology Technology:Proteolix Presents Preclinical Data for Oral Proteasome Inhibitor PR-047 at the 50th Annual Meeting of the American Society of Hematology 2Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 2Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 3Accuray Achieves Milestone of 150th CyberKnife System Installed Worldwide 4New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 2New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 3New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 4New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 5New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 6New Initiative Focuses on Water Quality Improvement in the Mississippi River Basin and Gulf of Mexico 7
(Date:11/25/2009)...ts at the California Institute of Technology (Calt...n-like behavior in the fruit fly, Drosophila mela...nt to the relationship between the neurotransmitte...order (ADHD), are described in the December issue ...n contains only about 20,000 neurons and has long ...
(Date:11/25/2009)...hters, police officers and ambulance workers faced...ter complex. They battled to save people from the ...ckled fires and evacuated as many people as they c...0 people. And making their jobs even harder was th...rs and their relatives jammed mobile networks with...
(Date:11/25/2009)...etime, the heart pumps some 250 million liters of ...he muscle fibers of the heart have to be extremely...g Rottbauer, vice chair of the Department of Medic...n: Prof. Dr. H. A. Katus), has discovered a protei...llest muscular unit, the sarcomere. In cooperation...
Breaking Biology News(10 mins):Caltech scientists find emotion-like behaviors, regulated by dopamine, in fruit flies 2Caltech scientists find emotion-like behaviors, regulated by dopamine, in fruit flies 3Caltech scientists find emotion-like behaviors, regulated by dopamine, in fruit flies 4Magic box for mission impossible 2Magic box for mission impossible 3New genetic cause of cardiac failure discovered 2Recoveries Secured by Philadelphia Personal Injury Law Firm Feldman Shepherd Rank among Top 50 in Pennsylvania and Top 100 in U S 50647 1Recoveries Secured by Philadelphia Personal Injury Law Firm Feldman Shepherd Rank among Top 50 in Pennsylvania and Top 100 in U S 50647 2Recoveries Secured by Philadelphia Personal Injury Law Firm Feldman Shepherd Rank among Top 50 in Pennsylvania and Top 100 in U S 50647 3Predicting the return of prostate cancer 3A New Johns Hopkins study betters the odds of success 50643 1Predicting the return of prostate cancer 3A New Johns Hopkins study betters the odds of success 50643 2Grant received for eye disorder research 50639 1Grant received for eye disorder research 50639 2
...y mapping the evolutionary history of animals indi...ture whose characteristics can only be inferred fr...ably significantly more complex than previously be...ional Science Foundation (NSF), is the cover story...high-powered technologies for analyzing massive vo...
...se is available in German . , , Halle/Saale. Mig...but not distance. These are the findings of a team...ity of Marburg, the Ornithological Society in Bava...earch (UFZ), writing in the Journal of Ornithology... of Asian birds from the leaf-warbler and thrush ...
...John Bell said QUT had worked with a Canberra-base...solar cells that act as both windows and energy ge...said the solar cell glass would make a significant...ts and could in fact generate excess energy that c...he glass was one of a number of practical technolo...
Other Biology News:And the first animal on Earth was a... 2And the first animal on Earth was a... 3Flying off course 2Flying off course 3
...multaneously perform 96 assays on one plate. The n... with 96 (7mm x 7mm) individual printing surfaces ..., or screening analysis studies. Unlike other syst..., eliminating the presence of contaminating adhesi...
...e NanoChip 400 System is an automated multiplexing... for performing SNP detection, pathogen sequence d...le samples with multiple targets can be applied to...anoChip cartridge, which may be reused until all t...
Rat siTrio from B-Bridge International
Phage Display cDNA Library Screening Kit from Spring Bioscience
Biology Products: