Navigation Links
Gladstone scientists identify strategy to reduce toxic proteins associated with Alzheimer's disease
Date:9/22/2010

enzyme known to add acetyl groups to proteins, the neurons had much less acetylated tau and toxic p-tau.

The research shows that the clearance of the toxic p-tau is blocked by acetylation. "The abnormally high levels of acetylation at early stages of the disease could lead to the formation of toxic protein aggregates in AD and other neurodegenerative diseases," explained Dr. Gan.

"This study suggests that interfering with tau acetylation may be a new approach for reducing tau-related pathology," said Dr. Mucke, GIND director. "In fact, Dr. Gan and her team have already identified a small molecule compound that eliminates toxic p-tau in neurons. It might represent a new class of anti-AD drugs."


'/>"/>

Contact: Valerie Tucker
vtucker@gladstone.ucsf.edu
415-734-2019
Gladstone Institutes
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology technology :

1. ORNL scientists reveal battery behavior at the nanoscale
2. Scientists observe single ions moving through tiny carbon-nanotube channel
3. Waters Corporation and UCLA to Convene Leading Life Scientists
4. Castor Bean Genome Published by Research Team Including Scientists from the Venter Institute
5. Scientists achieve highest-resolution MRI of a magnet
6. Univfy and Stanford Scientists Develop the First Personalized Prognostic Test to Predict Live Birth Outcomes with In Vitro Fertilization
7. Stanford scientists develop new way to grow adult stem cells in culture
8. Princeton scientists find unusual electrons that go with the flow
9. Twelve Women Scientists Announced as Winners of Elsevier Foundation TWOWS Awards
10. Scientists strive to replace silicon with graphene on nanocircuitry
11. Prestigious International Champalimaud Vision Award to US Scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... Kitware , a leading developer of ... award from the U.S. Department of Energy for the ... nuclear power industry. , Construction of nuclear power plants ... but the United States’ nuclear power industry has continued ... utilization through improved refueling, maintenance, and safety systems at ...
(Date:6/17/2013)... 17, 2013 NASA deployed ... that helps better monitor potentially harmful chemicals in the ... which was developed by Draper Laboratory , is ... Astronauts breathe air that is processed and re-circulated within ... in the air, even in trace amounts, endangers their ...
(Date:6/17/2013)... 2013  KaloBios Pharmaceuticals, Inc. (Nasdaq: KBIO ... Joseph as Chief Legal Officer.  Mr. Joseph brings ... and has worked in both public and private companies, ... (Logo: http://photos.prnewswire.com/prnh/20130225/MM66380LOGO ) "Don ... general counsel and senior executive and his knowledge and ...
(Date:6/17/2013)... June 17, 2013 As a leader in ... to finding a cure all for acne, rosacea, and eczema. ... AARS (Acne and Rosacea Society) has dedicated a ... helping to educate the public on treatment options. Probiotic Action ... announcing their daily news updates via social networks and online ...
Breaking Biology Technology:Kitware to Develop an Open-Source HPC Design-Analysis Environment for Nuclear Energy Research 2New Monitoring System Will Better Protect NASA Astronauts on ISS 2KaloBios Appoints Donald R. Joseph as Chief Legal Officer 2KaloBios Appoints Donald R. Joseph as Chief Legal Officer 3KaloBios Appoints Donald R. Joseph as Chief Legal Officer 4Acne and Rosacea Awareness Month: Probiotic Action Announces their Daily News Updates with Insight on the Most Common Skin Conditions 2
... ... The Chinese Biopharmaceutical Association-USA (CBA) announced ... 12 -13 in Maryland, US. ,The event will highlight ... It will also develop a platform for communication and collaboration ...
... the most resistant organisms on earth, carry an extra ... reports in the latest issue of the journal ... why spores of the bacteria that cause botulism, tetanus, ... study was conducted by researchers at New York University,s ...
... Technology, consisting of undergraduate student Sean Lyttle, along ... Zhenbo Fu and led by Professors David Cappelleri, ... of Mechanical Engineering, placed third in the Freestyle ... Technology (NIST) Mobile Microrobotics Challenge held at the ...
Cached Biology Technology:Chinese Biopharmaceutical Association Holds 15th Annual Conference in Rockville, MD, June 12 - 13 2Chinese Biopharmaceutical Association Holds 15th Annual Conference in Rockville, MD, June 12 - 13 3Biologists discover an extra layer of protection for bacterial spores 2Stevens team places third in 2010 IEEE/NIST Mobile Microrobotics Challenge 2
(Date:6/17/2013)... the U.S. exposed to high levels of air pollution while ... child with autism as women who lived in areas with ... of Public Health (HSPH). It is the first large national ... the U.S. , "Our findings raise concerns since, depending on ... study lived in areas where risk of autism was elevated," ...
(Date:6/17/2013)... locations with central nervous system infections may well be ... according to a study to be published in ... Society for Microbiology. Researchers have detected the virus in ... central nervous system infections of unknown cause, and in ... pigs and poultry, suggesting animals may serve as reservoirs ...
(Date:6/17/2013)... with severe brain infections in Vietnam. Further research is ... the symptoms of disease. , The virus was found ... with severe brain infections in the study, corresponding to ... patients with non-infectious brain disorders that were tested. , ... often fatal and patients who do survive, often young ...
Breaking Biology News(10 mins):Exposure to high pollution levels during pregnancy may increase risk of having child with autism 2New virus discovered in patients with central nervous system infections 2New virus discovered in patients with central nervous system infections 3New virus isolated from patients with severe brain infections 2New virus isolated from patients with severe brain infections 3
... designed to standardize and optimize the diagnosis, treatment, and ... uncommon and challenging form of thyroid cancer, have been ... ahead of print in Thyroid , a peer-reviewed ... ). The guidelines are available free online at ...
... step closer to building low cost networks of ... At the IEEE Reconfigurable Architectures Workshop in Rome, ... Jacobs School of Engineering presented a paper highlighting ... rather than competing hardware platforms for their experimental ...
... Aware, Inc. (Nasdaq: AWRE ), a leading ... results for its first quarter ended March 31, 2009. ... a decrease of 22% compared to $5.9 million in the ... and basic and diluted net income per share in accordance ...
Cached Biology News:First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal 2Toward cheap underwater sensor nets 2Toward cheap underwater sensor nets 3Aware, Inc. Reports First Quarter 2009 Financial Results 2Aware, Inc. Reports First Quarter 2009 Financial Results 3Aware, Inc. Reports First Quarter 2009 Financial Results 4Aware, Inc. Reports First Quarter 2009 Financial Results 5Aware, Inc. Reports First Quarter 2009 Financial Results 6
Goat polyclonal to SIAH Interacting Protein ( Abpromise for all tested applications)....
MAb to Transferrin Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business Days...
MAB3246 recognizes the neuro-endocrine specific protein (NSP) C....
PE Rat anti-Hu CD267 Storage Temperature: Refrigerate(2 to 8C)...
Biology Products: