Navigation Links
deCODE genetics Announces Third Quarter 2007 Financial Results
Date:11/5/2007

rability profiles in heart patients.

The company will use the results from this study to inform dose

selection for a larger Phase IIb trial planned to commence early next

year. The company is at the same time advancing the reformulation of

DG031, which also targets the leukotriene pathway for the prevention of

heart attack. The company has completed an accelerated 3-month

stability study with its lead reformulation and expects to complete

pharmacokinetic analysis of its bioequivalence study before the end of

this year.

-- DG041 for arterial thrombosis. In the past quarter deCODE has

successfully completed additional clinical studies with DG041, its

novel, first in class antagonist of the EP3 receptor for prostaglandins

E2. deCODE is developing DG041 as a next-generation oral anti-platelet

therapy -- a mechanism specific means of preventing arterial thrombosis

without increasing bleeding time. Clinical studies completed early this

summer demonstrated that in a concentration-dependent manner DG041

dramatically inhibits platelet activation mediated through vasodilator-

stimulated phosphoprotein (VASP) as well as platelet aggregation.

Moreover, the desired effect on VASP -- a biomarker useful for gauging

platelet activation -- appears to be achievable at doses lower than

previously anticipated. The company has built on those results in the

past quarter with the completion of two drug-drug interaction studies

that showed DG041 to have a very satisfactory DDI profile. Moreover, in

a double-blind, placebo-controlled clinical study, DG041 was shown to

have the desired effect on VASP, and in a significant and

concentration-dependent manner, irrespective of whether subjects were

also receiving aspirin. This supports DG041's development as a compoun
'/>"/>

SOURCE deCODE genetics
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. deCODE genetics to Webcast Presentation at Thomas Weisel Partners Annual Healthcare Conference
2. deCODE genetics Announces Webcast of Conference Call to Discuss Third Quarter 2007 Financial Results
3. Digital Unions RT1(TM) Software Creates Telegenetics Network for Region 3 Genetics Collaborative
4. Response Genetics Reports Second Quarter 2007 Financial Results
5. ZymoGenetics Will Hold Conference Call Today at 5:00 p.m. Eastern Time to Provide Update on rThrombin
6. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
7. ZymoGenetics to Webcast Presentation at Two Upcoming Conferences
8. Interleukin Genetics Announces Management and Board Appointments
9. Response Genetics Announces Presentations/Webcasts at Upcoming Investor Conferences
10. Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference
11. CellCyte Genetics Corp. Forms Device Division to Develop and Manufacture Stem Cell Cultivation and Replication Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... Each year in the US, ... attention. In the military, burn injury is a ... medical care. More than 800 service members sustained ... heal slowly, remain inflamed and often become infected, ... and functionally damaging. While developments in supportive care ...
(Date:9/29/2014)... the start of the military conflicts in Iraq and ... United States with traumatic brain injury caused by exposure ... improvised explosive devices, or IEDs. Symptoms of traumatic brain ... headaches and nausea, to more severe impairments in memory ... of Defense has recognized the critical importance and complexity ...
(Date:9/29/2014)... Sept. 29, 2014 Research and Markets ... Market by Product & Services, End-User , Application - ... The global oligonucleotide synthesis market is ... million in 2014, growing at a CAGR of 9.8% ... is categorized on the basis of products and services, ...
(Date:9/29/2014)... food security, emerging diseases and biodiversity loss requires ... in Science Express that was co-authored ... College of Agriculture and Life Sciences. , For ... scientists has reviewed progress in addressing a broad ... management using approaches that consider evolutionary histories and ...
Breaking Biology Technology:Faster Healing with Fewer Scars 2Modeling shockwaves through the brain 2Modeling shockwaves through the brain 3Modeling shockwaves through the brain 4Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 2Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 3Evolutionary biology: It's not just for textbooks anymore 2Evolutionary biology: It's not just for textbooks anymore 3
... breaches - ... - ... 29 Protein Sciences Corporation,("PSC") announced today that the sale of ... Inc. (NYSE: EBS ),and its affiliate (collectively "Emergent") has been ...
... 29 /PRNewswire-FirstCall/ - Par,Pharmaceutical Companies, Inc. (NYSE: PRX ... and live webcast on Friday, August 8, 2008 at ... ended June 28, 2008. The,Company will release results after ... release will be available on the Par website at, ...
... Event Expected to Attract a Record Number of ... ... DeviceSpace(TM), the world,s,leading online medical device and diagnostics job board ... Minnesota on,Monday, September 8, 2008. The event will take place at ...
Cached Biology Technology:Protein Sciences Announces Termination of Deal to Sell to Emergent BioSolutions 2DeviceSpace(TM) to Host Medical Device and Diagnostics Career Fair in Minneapolis 2
(Date:9/30/2014)... research, involving mice and published in the October 2014 ... , suggests that just because you can do ... team of Italian scientists have found that using marijuana ... immune system. This damage may result in autoimmune diseases ... bowel disease and rheumatoid arthritis in adulthood. , "I ...
(Date:9/30/2014)... some hope: A new research report published in October ... , explains how scientists developed a synthetic version of ... development in human and mouse eggs similar to the ... during fertilization. , "We believe that the results of ... understanding of human fertilization by providing a precise answer ...
(Date:9/30/2014)... of perilous threats in today,s ocean. From overfishing ... fragile coral ecosystems are disappearing at unprecedented rates ... of corals surrounding the island of Moorea in ... tropical environment: coral guard-crabs. New research from the ... scientist Seabird McKeon and the museum,s predoctoral fellow ...
Breaking Biology News(10 mins):Adolescent exposure to thc may cause immune systems to go up in smoke 2Synthetic sperm protein raises the chance for successful in vitro fertilization 2Smithsonian scientists discover coral's best defender against an army of sea stars 2
... of different cancers actually share something in common ?a molecular ... microRNA (miRNA) that target key cancer genes and promote malignant ... as an emerging class of gene regulators and may also ... , The study appears online in the Proceedings of ...
... have for the first time reconstructed the Darwinian evolution ... research was led by Joe Thornton, assistant professor of ... and Evolutionary Biology, and will be published in the ... can drive the evolution of complex molecular systems ?those ...
... UT Southwestern Medical Center ophthalmologists will be the first in ... to fix nearsightedness. , "Think of it as a contact ... who is inserting the new implantable collamer lens, or ICL, ... , The ICL can replace or reduce the need for ...
Cached Biology News:Common molecular 'signature' identified in solid tumors 2Common molecular 'signature' identified in solid tumors 3Evolution of 'irreducible complexity' explained 2New 'implanted contacts' designed to fix nearsightedness 2
... from KUBTEC is a dual capability system with ... representation of the specimen under test. While the ... images, the micro focus source also allows the ... standard 2D images. The 50 mm x 50 ...
... electroporation products and specialty electrodes, has developed ... experiment optimization and large volume electroporation. The ... Molecular Delivery. The days of researchers struggling ... the number of samples and cell types ...
... (PR) Competitor Assay Kits are ideal ... receptor binding compounds using fluorescence polarization ... fusion of glutathione transferase to the ... receptor [PR-LBD(GST)] and a proprietary, fluorescently ...
... Kodak Companys Molecular Imaging Systems group ... Station 4000 Digital Imaging Systems, featuring ... for comprehensive fluorescence, luminescence, radiographic and ... million pixel CCD and 10x optical ...
Biology Products: