Navigation Links
deCODE genetics Announces Third Quarter 2007 Financial Results
Date:11/5/2007

e have recently completed two studies confirming the lack of undesirable drug-drug interactions, as well as a pharmacology study of its effects in the presence and absence of aspirin. The results of that study provide further evidence that DG041 inhibits platelet activation and aggregation through a crucial pathway that is not targeted by existing medications. In order to manage risk and expand our therapeutic pipeline, we are actively investigating partnership opportunities for these and earlier stage programs. Our financial results this year demonstrate our ability to create valuable assets through product development while leveraging our capabilities to generate near-term revenue streams," Dr. Stefansson concluded.

Recent highlights include:

Product Development

-- Heart attack. In its drug development program targeting the leukotriene

pathway for the prevention of heart attack, deCODE last month began

enrolling patients for its Phase IIa clinical trial for DG051, the

company's leukotriene A4 hydrolase inhibitor. In Phase I studies

completed earlier this year, DG051 significantly reduced the production

of leukotriene B4 (LTB4) in a dose dependent manner. LTB4 is a pro-

inflammatory molecule that deCODE's gene discovery and functional

biology work identified as a key factor in modulating risk of heart

attack. The Phase I studies showed DG051 to be safe and well-tolerated

at all dose levels tested, with a favourable pharmacokinetic profile.

DG051 was also recently evaluated in a 28-day Phase I study that

further demonstrated that the drug can deliver significant, sustained

reductions in LTB4 levels with once-daily dosing. The Phase IIa is a

randomized, double-blind, placebo-controlled trial that will examine

the impact of DG051 on the production of LTB4 as well as the compound's

pharmacokinetic and safety and tole
'/>"/>

SOURCE deCODE genetics
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. deCODE genetics to Webcast Presentation at Thomas Weisel Partners Annual Healthcare Conference
2. deCODE genetics Announces Webcast of Conference Call to Discuss Third Quarter 2007 Financial Results
3. Digital Unions RT1(TM) Software Creates Telegenetics Network for Region 3 Genetics Collaborative
4. Response Genetics Reports Second Quarter 2007 Financial Results
5. ZymoGenetics Will Hold Conference Call Today at 5:00 p.m. Eastern Time to Provide Update on rThrombin
6. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
7. ZymoGenetics to Webcast Presentation at Two Upcoming Conferences
8. Interleukin Genetics Announces Management and Board Appointments
9. Response Genetics Announces Presentations/Webcasts at Upcoming Investor Conferences
10. Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference
11. CellCyte Genetics Corp. Forms Device Division to Develop and Manufacture Stem Cell Cultivation and Replication Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... D.C., September 30, 2014 Applying a well-known ... researchers at Harvard University has demonstrated the ability ... -- work that holds promise for making future, ... detailing the sides of next-gen rocket ships and ... light passes through oil in water, it becomes ...
(Date:9/30/2014)... 30, 2014 Shimadzu Scientific Instruments ... easy-to-use and highly precise tool for measuring displacement ... elongation. With 1000-mm maximum movement distance, the DSES-1000 ... a gauge length of 10 mm. In addition, ... above 50-mm stroke and within +/- 100 µm ...
(Date:9/30/2014)... Md. , Sept. 30, 2014  RegeneRx ... today announced that it has received a Canadian ... by Actin-Sequestering Peptides.  This patent includes claims using ... numerous other actin-sequestering peptides for these purposes.  The ... About RegeneRx Biopharmaceuticals, Inc. ( www.regenerx.com ) ...
(Date:9/30/2014)... Sept. 30, 2014  KemPharm, Inc., a clinical-stage ... development of proprietary new molecular entity (NME) prodrugs, ... Trademark Office (USPTO) issued U.S. Patent No. 8,816,083 ... Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid ... Use Thereof." The patent, which extends ...
Breaking Biology Technology:Taking thin films to the extreme 2Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2RegeneRx Receives Canadian Patent for Inhibition or Reversal of Skin Aging 2KemPharm, Inc. Receives Patent from the USPTO for Novel Prodrug of Hydromorphone, KP511 2
... Vice President of Regulatory Affairs and Vice President of ... ... NGSX ), a biopharmaceutical company focused on developing novel,pain management ... of Regulatory Affairs and Russell Kawahata, Ph.D. as,the Vice President of ...
... WAYNE, N.J., Oct. 9 A homegrown New ... that safeguards,the pedigree of pharmaceuticals everywhere. Secure Symbology, ... been chosen as an,Honored Finalist as Emerging Business ... being recognized for its vision to wipe out ...
... University HealthSystem Consortium With Broad ... Portfolio of ... (NYSE: BAX ) announced today that Novation, the University ... extension on behalf of UHC valued at over $200 million ...
Cached Biology Technology:NeurogesX Expands Senior Management Team 2NeurogesX Expands Senior Management Team 3Secure Symbology: Making New Jersey Proud While Saving Lives 2Baxter and Novation Sign Multi-Year Contract Extension Valued at Over $200 Million for Medication Delivery Products 2Baxter and Novation Sign Multi-Year Contract Extension Valued at Over $200 Million for Medication Delivery Products 3
(Date:9/30/2014)... of tourists visit the Mediterranean each year, but ... underway on Earth. Almost 1,000 alien species, including ... other seas through human activities. In the open-access ... multinational team of researchers analyzed data from a ... to show how the introduction of alien species ...
(Date:9/30/2014)... watermelon, salmon, and strawberries all have in common? ... of chromosomes and are diploid, these organisms are all ... chromosomesseedless watermelon and salmon have 3 and 4 sets ... this might seem surprising, in fact most plant species ... over a century ago, but only recently, with the ...
(Date:9/30/2014)... Prenatal exposure to tetrachloroethylene (PCE) in drinking water ... abruption, according to a new study led by ... , The study, published in the journal ... 1,019 unexposed pregnancies among 1,766 women in Cape ... late 1960s to the early 1980s by the ...
Breaking Biology News(10 mins):Biodiversity in the Mediterranean is threatened by alien species 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4Contaminated water linked to pregnancy complications, BU study finds 2
... A team of scientists from The Scripps Research Institute, ... among other institutions, has created a genetically modified fruit ... common neurodegenerative disorder that strikes about one out of ... As described in an article published in an Early ...
... , This release is available in ... of cells. Underneath their smooth surface they harbor an ... bottleneck like invaginations, which expand into elongated cavities (cristae). ... the cristae (,crista junction,) allows separation of the intracristal ...
... A two-tiered scanning-protocol for inspecting all containers at international ... containers moving through the global transportation system are not ... at a services special interest group meeting of the ... , The authors challenge the federal scheme now in ...
Cached Biology News:Scripps Research scientists observe human neurodegenerative disorder in fruit flies 2Scripps Research scientists observe human neurodegenerative disorder in fruit flies 3How mitochondria get their membranes bent 2Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 2Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 3Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 4
...
...
LECHNER AND LaVECK MEDIUMfor the clonal growth of normal human bronchial and other epithelial cells. Requires additives. With glutamine.Recommended storage condition:oC to 8oCIntended use(s):research...
... The GeneSwitch Cell Lines stably ... pSwitch. Each cell line is functionally ... transfection with the expression control vector ... expression after treatment with mifepristone (Figure ...
Biology Products: