ome that impact
bone mineral density (BMD) and predispose to fracturing of bones. BMD is a
principal measure of the presence and severity of osteoporosis, a common,
progressive and often debilitating condition in which bones become thinner
and more prone to fracture, even from minor falls or blows. As an editorial
in the New England Journal of Medicine points out, although BMD has long
been known to have a significant inherited component, these are the first
validated and replicated genetic variants ever linked to BMD through a
genome-wide scan of SNPs. Although these variants confer an increase in
risk that is in the range of 5-15% compared to non-carriers of the
variants, they are all quite common and so may account for a sizable
proportion of the inherited component of low BMD.
About deCODE
deCODE is a biopharmaceutical company applying its discoveries in human
genetics to the development of diagnostics and drugs for common diseases.
deCODE is a global leader in gene discovery -- our population approach and
resources have enabled us to isolate key genes contributing to major public
health challenges from cardiovascular disease to cancer, genes that are
providing us with drug targets rooted in the basic biology of disease.
Through its CLIA-registered laboratory, deCODE is offering a growing range
of DNA-based tests for gauging risk and empowering prevention of common
diseases, including deCODE T2(TM) for type 2 diabetes; deCODE AF(TM) for
atrial fibrillation and stroke; deCODE MI(TM) for heart attack; deCODE
ProCa(TM) for prostate cancer; and deCODE Glaucoma(TM) for a major type of
glaucoma. deCODE is delivering on the promise of the new genetics.(SM)
Visit us on the web at http://www.decode.com; on our diagnostics site at
http://www.decodediagnostics.com; and, for our pioneering personal genome analysis
service, at
SOURCE deCODE genetics Copyright©2008 PR Newswire. All rights reserved | |
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