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deCODE's growing list of tests include deCODE T2(TM), for assessing
inherited risk of type 2 diabetes; deCODE AF(TM), for assessing risk of
atrial fibrillation, a common precursor of stroke; deCODE MI(TM), a
test for a major genetic risk factor for early-onset heart attack as
well as abdominal aortic and intracranial aneurysms; deCODE ProCa(TM),
which detects several significant genetic risk variants for prostate
cancer; and we have recently completed work on a test for assessing
inherited risk of a major type of glaucoma.
-- deCODEme(TM). Bringing together deCODE's leadership in human genetics
and recent advances in genotyping technology, in November 2007 deCODE
launched the first personal genome analysis service: deCODEme(TM). The
service takes advantage of deCODE's leadership in human genetics and
its whole-genome genotyping capabilities. Through deCODEme(TM),
subscribers can put themselves in the context of the latest discoveries
in genetics, learning what their own DNA says about their ancestry,
certain physical traits, as well as whether they have genetic variants
that have been associated with higher or lower than average risk of a
range of common diseases. This information is continually updated as
new discoveries are made, and is presented in the subscriber's secure
individual web page.
-- Arterial thrombosis: DG041. DG041 is deCODE's novel, first-in-class
antagonist of the EP3 receptor for prostaglandins E2, being developed
as a next-generation oral anti-platelet therapy for preventing arterial
thrombosis without increasing bleeding time. In a Phase II clinical
trial and additional clinical pharmacology studies completed in 2007,
DG041 was shown to dramatically inhibit platelet
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