Navigation Links
deCODE Discovers Genetic Risk Factor Linking Susceptibility to Four Major Vascular Diseases
Date:7/12/2010

REYKJAVIK, Iceland, July 12, 2010 /PRNewswire-FirstCall/ -- Points to Novel Pathway for Drug Discovery, Will be Incorporated Into Tests to Improve Screening and Early Detection of Abdominal Aortic Aneurysm, Heart Attack and PAD

Scientists at deCODE genetics and academic colleagues from the Netherlands and twelve other countries across Europe and North America today report the discovery of a common single-letter variation (SNP) in the sequence of the human genome conferring risk of a range of vascular diseases. The SNP confers risk of abdominal aortic aneurysm (AAA), early-onset heart attack, peripheral artery disease (PAD), and pulmonary embolism, independent of other known risk factors. It will be integrated into deCODE's DNA-based tests to improve the assessment of individual risk and the targeting of screening and prevention strategies. The SNP, rs7025486, is located in an intron of the DAB21P gene on chromosome 9q33. The gene encodes an inhibitor of cell growth and survival that is expressed in cardiovascular tissue.

"This is the sort of discovery that makes human genetics such an exciting field of endeavour. By incorporating this with other major genetic risk factors we include in our tests, such as those on 9p21, we are empowering physicians to identify greater numbers of those at high risk and who should therefore benefit from closer monitoring and prevention strategies. In the case of AAA, for example, this can be used along with traditional risk factors to identify those who should have ultrasound screening, leading to the detection of more aneurysms earlier, potentially saving lives," said Kari Stefansson, deCODE's executive
'/>"/>

SOURCE DeCODE Genetics Inc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. deCODE Finds Genetic Factors Impacting Key Clinical Measurements of Heart Activity and Disease Risk
2. deCODE Receives Delisting Notice From Nasdaq, Plans to Appeal
3. deCODE genetics, Inc. Announces Approval of First Day Motions by Bankruptcy Court
4. Amaizing: Corn genome decoded
5. deCODE Receives Nasdaq Bid Price Deficiency Notice
6. deCODE genetics Announces Second Quarter 2009 Financial Results
7. deCODE genetics Announces Webcast of Conference Call to Discuss Second Quarter 2009 Financial Results
8. Its Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer
9. deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis
10. deCODE Reinstated to Nasdaq Global Market
11. deCODE Genotyping Laboratory Receives College of American Pathologists Accreditation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... April 17, 2015 Reed Technology ... in regulatory data management, preparation, and submission to the ... availability of a new Lot Distribution Report (LDR) service ... to remain compliant with the FDA’s new rule on ... FDA to monitor the volume and timing of particular ...
(Date:4/17/2015)... April 17, 2015 /PRNewswire/ - SQI Diagnostics Inc. (TSX-V: ... company that develops and commercializes proprietary technologies and ... that it has received approval from the TSX ... outstanding common share purchase warrants ("the Warrants") of ... the Company,s May 2013 private placement financing. ...
(Date:4/17/2015)... , April 17, 2015  US-Australian drug discovery company, ... Memorandum of Understanding with the Feinstein Institute for ... York to collaborate with the objective ... The collaboration brings together the drug discovery ... expertise of the Feinstein Institute in neurosciences and ...
(Date:4/17/2015)... LC Sciences LLC, a leading developer ... it is seeking beta testers for the VariantPro™ ... targeted sequencing technology. The system offers cost-effective, minimal ... detection of rare variants. It utilizes novel and ... will collaborate with beta testers to generate test ...
Breaking Biology Technology:Reed Tech Announces FDA Lot Distribution Report (LDR) Service for Manufacturers of Biologic Products 2Reed Tech Announces FDA Lot Distribution Report (LDR) Service for Manufacturers of Biologic Products 3SQI Diagnostics to Extend Warrant Expiry 2SQI Diagnostics to Extend Warrant Expiry 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 2LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 3
... Online brand protection firms could be the answer to a ... , ,The Internet does connect you with your customers ... and e-mails that could damage your reputation and sales. Here ... from the simple to the sophisticated, and suggestions for dealing ...
... Editor's note: As the director of technology programs for the ... is at the forefront of trends in information technology workforce ... the market need for courses that help IT professionals in ... part two next week. , , Scott Converse also ...
... Madison, Wis. - When Cytochroma , a ... acquired the Madison-based Proventiv Therapeutics last year, executives indicated ... $25 million in venture capital from Canadian and American ... from two Canadian funds. , ,The company, which says ...
Cached Biology Technology:Protecting your business against online brand abuse 2Protecting your business against online brand abuse 3Biotech with Madison ties raises $21M in capital 2
(Date:3/23/2015)... Mar. 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... the growing mobile commerce market, announces its biometric payment technology, ... on CNBC television starting March 30 th . ... in New York markets. ... are excited about our new ad campaign following the recent ...
(Date:3/20/2015)... Conn. , March 20, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... smart wallet is one of the products featured in ... March 20th at 11:00 PM EST on the DIY ... to Las Vegas , site of ...
(Date:3/18/2015)... March 18, 2015 As mobile payments ... revolutionary smart wallets and apps continue to be introduced into ... in the mobile payment industry in focus today are:  NXT-ID, ... (NYSE: BABA ), Apple Inc. (NASDAQ: ... Facebook Inc. (NASDAQ: FB ) NXT-ID, ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
... with water to produce hydrogen almost instantaneously, according to ... experiments, the scientists created spherical silicon particles about 10 ... reacted to form silicic acid (a nontoxic byproduct) and ... cells. The reaction didn,t require any light, heat ...
... working out the structure of a cell-killing protein produced ... , researchers stumbled on a bit of unusual biochemistry. ... different, three-dimensional ring structures in the protein, one of ... findings, reported in Nature Chemical Biology , should ...
... 2012) Wildlife Conservation Society scientists have documented a thriving ... grassland-dwelling herbivore with the trunk-like snout living in ... border. Using a combination of camera traps, ... WCS estimates at least 14,500 lowland tapirs in the ...
Cached Biology News:Just add water: How scientists are using silicon to produce hydrogen on demand 2Study: Odd biochemistry yields lethal bacterial protein 2Study: Odd biochemistry yields lethal bacterial protein 3Paradise found for Latin America's largest land mammal 2