Navigation Links
deCODE Discovers Fourth Major Set of Common Genetic Variants Linked to Risk of Estrogen Receptor-Positive Breast Cancer
Date:4/27/2008

chromosome 5p12.

deCODE gratefully acknowledges the participation of the patients and researchers who took part in this study.

About Breast Cancer

Breast cancer is the most common cancer and the second leading cause of cancer deaths among women. Breast cancers are classified as ER+ or ER- according to whether tumors are found to contain estrogen receptors; in women of European descent approximately three-quarters are ER+, and in women of African descent approximately 50% are ER+. An estimated 178,000 cases are diagnosed in the US every year and over 40,000 deaths will result from breast cancer. Though a substantial portion of risk of this common disease is clearly familial, it has taken painstaking research to find genetic variants predisposing to its common forms. The strongly predisposing mutations in the BRCA1 and BRCA2 genes have a less than 0.5% frequency in the general population in the US and Europe. These mutations are estimated to account for only 1-3% of all breast cancer cases. There is evidence that a substantial portion of the uncharacterized risk for breast cancer is genetic, and this has encouraged the search for additional breast cancer predisposition genes.

About deCODE

deCODE is a biopharmaceutical company applying its discoveries in human genetics to the development of diagnostics and drugs for common diseases. deCODE is a global leader in gene discovery - our population approach and resources have enabled us to isolate key genes contributing to major public health challenges from cardiovascular disease to cancer, genes that are providing us with drug targets rooted in the basic biology of disease. Through its CLIA-certified laboratory, deCODE is offering a growing range of DNA-based tests for gauging risk and empowering prevention of common diseases, including deCODE T2(TM) for type 2 diabetes; deCODE AF(TM) for atrial fibrillation and stroke; deCODE MI(TM) for heart attack; and deCODE PrCa(TM) for prostate can
'/>"/>

SOURCE deCODE genetics
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. deCODE Lauds Federal Legislation to Ban Discrimination on the Basis of Genetic Information
2. deCODE genetics Announces Webcast of Conference Call to Discuss First Quarter 2008 Financial Results
3. U.S. Preventive Medicine and deCODE Genetics Sign Letter of Intent to Expand Personalized Medicine Platform
4. A Smoking Gene: deCODE Shows How a Single Variant in the Sequence of the Genome Confers Nicotine Dependence and Risk of Lung Cancer and Other Disease
5. deCODE genetics to Webcast Presentation at 15th Annual Future Leaders in the Biotech Industry Conference
6. deCODE genetics to Webcast Presentation at Lehman Brothers Eleventh Annual Global Healthcare Conference
7. deCODE Genetics Announces Full-year 2007 Financial Results
8. deCODE genetics Announces Webcast of Conference Call to Discuss Full-year 2007 Financial Results
9. deCODE genetics to Webcast Presentation at BIO CEO and Investor Conference
10. deCODE Discovers Gene Variants that May Help to Distribute the Work of Evolution between Men and Women
11. deCODE genetics to Webcast Presentation at JPMorgan Annual Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... May 17, 2013 New ... most innovative thought leaders of the medical device ... East conference and expo, from June 18-20 in ... (Photo: http://photos.prnewswire.com/prnh/20130517/613829 ) , ... deliver industry professionals practical presentations and implementable solutions ...
(Date:5/17/2013)... , May 17, 2013 /PRNewswire-iReach/ -- Aridis is ... reached with Switzerland -based Kenta ... human monoclonal antibody (mAb) products, and technologies. This ... products for treatment of infections by common pathogens ... aureus , Pseudomonas aeruginosa , Acinetobacter ...
(Date:5/17/2013)... 2013 The paradigm of ‘one drug, ... that can help predict the adverse and therapeutic effects ... Head of Computational Biology at the Genomics Laboratory, Covance, ... ensure high-quality genomics when used as part of the ... complex data sets to identify key clinical targets even ...
(Date:5/17/2013)... IAC Industries wants to share with you the success ... set up and furnish a research lab knowing that the ... year’s time. How does a company make choices in lab ... is efficient and cost-effective? , The solution was the ... planners at DisperSol determined that the concept of modular lab ...
Breaking Biology Technology:MedTech Innovate Seminars: New Interactive Learning Forums at 2013 MD&M East 2Aridis Pharmaceuticals Announces Acquisition of Monoclonal Antibody Products and Technologies From Kenta Biotech 2Aridis Pharmaceuticals Announces Acquisition of Monoclonal Antibody Products and Technologies From Kenta Biotech 3New Downloadable Success Story: “How To Outfit a Dynamic Lab in Flux” 2
... Mass., July 23 NxStage Medical,Inc. (Nasdaq: ... today announced ongoing public access to current summary,information ... end-stage,renal-disease (ESRD) who undergo hemodialysis at home on ... to the conventional regimen of therapy,received three times ...
... WILMINGTON, Del., July 23 More than a ... AZN ) to inquire about the,company,s prescription savings ... pharmacists, according to a year-long survey of more ... percent of the patients who called,AstraZeneca,s information center ...
... Future, CAMBRIDGE, Mass., July 23 Genzyme Corporation,(Nasdaq: ... growth in the second,quarter, along with significant progress in ... to approximately $1.171 billion from,$933.4 million in last year,s ... areas of the business., GAAP net income was ...
Cached Biology Technology:NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 2NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 3NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 4NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 5AstraZeneca Survey: Healthcare Professionals Leading Source of Information on Company's Prescription Savings Programs 2AstraZeneca Survey: Healthcare Professionals Leading Source of Information on Company's Prescription Savings Programs 3Genzyme Reports Strong Second-Quarter Growth 2Genzyme Reports Strong Second-Quarter Growth 3Genzyme Reports Strong Second-Quarter Growth 4Genzyme Reports Strong Second-Quarter Growth 5Genzyme Reports Strong Second-Quarter Growth 6Genzyme Reports Strong Second-Quarter Growth 7Genzyme Reports Strong Second-Quarter Growth 8Genzyme Reports Strong Second-Quarter Growth 9Genzyme Reports Strong Second-Quarter Growth 10Genzyme Reports Strong Second-Quarter Growth 11Genzyme Reports Strong Second-Quarter Growth 12Genzyme Reports Strong Second-Quarter Growth 13Genzyme Reports Strong Second-Quarter Growth 14Genzyme Reports Strong Second-Quarter Growth 15Genzyme Reports Strong Second-Quarter Growth 16Genzyme Reports Strong Second-Quarter Growth 17
(Date:5/16/2013)... MD FASEB MARC (Maximizing Access to Research ... for The Society for Developmental Biology (SDB) 72nd ... 2013. These awards are meant to promote the ... groups into the mainstream of the basic science ... scientists at the SDB 2013 Annual Meeting. , ...
(Date:5/16/2013)... the stability of today,s largest ice sheets in Greenland and ... ago, for example when Earth was going through a ... high sea level due to ice sheet collapse at that ... if the world,s largest ice sheets collapsed in the past, ... progressively warming world. , However, a new groundbreaking study ...
(Date:5/16/2013)... -- Injectable nanoparticles developed at MIT may someday ... diabetes to constantly monitor their blood-sugar levels and ... designed to sense glucose levels in the body ... insulin, thereby replacing the function of pancreatic islet ... 1 diabetes. Ultimately, this type of system could ...
Breaking Biology News(10 mins):World's biggest ice sheets likely more stable than previously believed 2Nanotechnology could help fight diabetes 2Nanotechnology could help fight diabetes 3
... on algae, researchers at UT Southwestern Medical Center have found ... responsible for a cell's response to external signals. , Cilia ... sperm cells to make fertilization possible, line the nose to ... , With such a range of abilities, cilia serve ...
... someone say 'yes', coffee can help. Moderate amounts ... to which we can be persuaded, finds research published ... The Australian researchers from the University of Queensland found ... attend to, and agree with, persuasive arguments. , The ...
... cheaper, more effective liver cancer treatment, reports Lisa Richards ... over 2,800 people in the UK each year, of ... Surgery is the best option, but is unsuitable for ... chemotherapy. The American Cancer Society estimates that 18,510 new ...
Cached Biology News:'Cellular antennae' on algae give clues to how human cells receive signals 2
The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver une...
... The EZ DNA Methylation Kit uses ... method for DNA methylation analysis. The kit ... that takes place between cytosine and sodium ... The EZ DNA Methylation Kits innovative in-column ...
... intended for laboratory research use only. ... buffered formalin and embedded in paraffin. ... certified pathologists. Tissue cores were removed ... a new recipient paraffin block, in an ...
... intended for laboratory research use only. ... buffered formalin and embedded in paraffin. ... certified pathologists. Tissue cores were removed ... a new recipient paraffin block, in an ...
Biology Products: