Navigation Links
Chimerix and BARDA Reach Agreement Ending GAO Review of Smallpox Antiviral Contract
Date:6/27/2011

to have reached a rapid resolution of the GAO protest so that all parties can continue with the important work of developing smallpox antivirals," said Kenneth I. Moch, President & CEO of Chimerix.  "Chimerix is intensely focused on developing CMX001, for its dual-use potential and as a potent broad spectrum antiviral, to address the threat of smallpox release and the critical needs of immunosuppressed transplant and oncology patients with life-threatening viral infections."

About CMX001

CMX001 is being developed as a potential broad spectrum oral antiviral for the treatment of life-threatening double-stranded DNA (dsDNA) viral diseases, including herpes viruses, adenoviruses and orthopox viruses.  The growing body of evidence of CMX001's antiviral activity against all five families of dsDNA viruses that cause morbidity and mortality in humans, including smallpox, has strengthened the compound's potential as a dual-use product prescribed as a traditional pharmaceutical and stockpiled as a biodefense countermeasure. More than 500 patients have been dosed with CMX001 to date in ongoing placebo-controlled clinical trials and in open-label treatment protocols for the prophylaxis, preemption and treatment of dsDNA viral diseases.  250 patients have received CMX001 under Emergency Investigational New Drug Applications (EINDs), including for treatment of orthopox viruses.  A significant number of the individuals receiving CMX001 in human testing have been immunocompromised as a result of disease or immunosuppressing therapies associated with stem cell or solid organ transplantation.

Clinical studies of CMX001 include: an ongoing Phase 2 study of the prevention/control of cytomegalovirus (a herpes virus) in adult hematopoietic stem cell transplant patients (CMX001-201); a Phase 2 study currently being initiated for the treatment of adenovirus infection in pediatric and adult hematopoietic stem cell transplant patients (AdV
'/>"/>

SOURCE Chimerix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related biology technology :

1. Chimerix to Present at Two Upcoming Investor Conferences
2. Chimerix Awarded BARDA Contract for Advanced Development of Broad Spectrum Antiviral CMX001 as Medical Countermeasure Against Smallpox
3. Chimerix Completes $45 Million Financing to Fund Further Development of Novel Antiviral Therapeutics CMX001 and CMX157
4. Chimerix Presents Update on CMX001 Development to the World Health Organization Advisory Committee on Variola Virus Research
5. Chimerixs PIM Conjugate Technology Reduces Risk of Nephrotoxicity for CMX001 and CMX157
6. Chimerix Appoints Two New Vice Presidents to Clinical Management Team
7. Chimerix to Present at Upcoming Investor Conferences
8. Chimerix Initiates Phase 1 Study of CMX157
9. Chimerix Names George Painter, Ph.D., Chairman of the Board and Chief Scientific Officer; Appoints Kenneth I. Moch President and Chief Executive Officer
10. Chimerix Names Wendy Painter, M.D., M.P.H., as Chief Medical Officer
11. Chimerix, Inc. Appoints Kenneth I. Moch Chief Operating Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... June 18, 2013 The Regulatory ... of two new offices in Asia—one in Singapore and ... serve as RAPS’ Pan-Asia office , serving the ... more focused on audiences within China. , The announcement ... partnership with five Singapore government agencies to develop and ...
(Date:6/18/2013)... DuPont welcomes 48 of the nation’s ... National AgriScience Teachers Ambassador Academy this week (NATAA) at ... , The NATAA “Ag Academy” is a ... special project of the National FFA Foundation ... . The highly recommended agriscience teachers, who are ...
(Date:6/18/2013)... Delaware , June 18, 2013 ... announce the release of the HELM biomolecular representation ... open source MIT licence. HELM (Hierarchical ... a wide range of biomolecules (e.g. proteins, nucleotides, ... existing small-molecule and sequence-based informatics methodologies impractical or ...
(Date:6/18/2013)... , June 18, 2013  AMRI (NASDAQ: ... Burlington, Mass. , site has ... Enforcement Administration (DEA) registration to handle Schedule 2 ... DEA,s acknowledgement of Burlington,s ... and documentation. (Logo: http://photos.prnewswire.com/prnh/20120229/NY61160LOGO ) ...
Breaking Biology Technology:RAPS Opens Offices in Singapore and China 2RAPS Opens Offices in Singapore and China 3DuPont Sponsors National AgriScience Ambassador Academy 2DuPont Sponsors National AgriScience Ambassador Academy 3The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2AMRI Burlington Receives DEA Approval to Handle Controlled Substances 2
... Percutaneous Systems, Inc.,(PercSys) announced today that it has ... Board of Directors. They include David Auth, Ph.D., ... Howard,Palefsky, a leading med-tech venture capitalist., "PercSys ... two of,the legendary figures of the medical device ...
... Offers Promising Patient Solutions, MARQUETTE, Mich., ... leader in innovative medical devices, announced today ... inter-body spacer. The,nanOss(TM)- Cervical cage is machined ... designed to function as bone.,The surgeries were ...
... in Third Quarter of 2008 Expands Worldwide ... Cutting-Edge Influenza Vaccine Technology, GAITHERSBURG, Md., Oct. ... its proprietary reverse genetics intellectual property,to Omninvest, a ... and construction of new vaccine strains to produce ...
Cached Biology Technology:PercSys Names David Auth and Howard Palefsky to Its Board of Directors 2Pioneer(R) Surgical Technology Announces First Human Implants of New nanOss(TM)-Cervical Fusion Device 2MedImmune Licenses Reverse Genetics Technology to Hungary's Omninvest for Use in Influenza Vaccine Development and Production 2
(Date:6/18/2013)... at the University of Calgary,s Faculty of Medicine have ... body from harmful bacteria. Platelets, a component of blood ... for specific bacteria, and upon detection, seal it off ... were published in Nature Immunology this week, ... immunity. , "The science community has known that platelets ...
(Date:6/18/2013)... "dead zone" in the Gulf of Mexico and a ... this year, based on several NOAA-supported forecast models. , ... University, and the Louisiana Universities Marine Consortium are ... zone will be between 7,286 and 8,561 square miles ... That would range from an area the size of ...
(Date:6/18/2013)... MD, June 18, 2013: The Association for Molecular Pathology ... of American Societies for Experimental Biology (FASEB) on July ... membership on June 3, 2013. , The 26 ... and share a common vision for the advancement of ... biomedical and translational research is more important now than ...
Breaking Biology News(10 mins):Immunity mechanism discovered 2NOAA, partners predict possible record-setting deadzone for Gulf of Mexico 2NOAA, partners predict possible record-setting deadzone for Gulf of Mexico 3NOAA, partners predict possible record-setting deadzone for Gulf of Mexico 4
... 12 Industry Leaders Chosen for BOSS-UROCKVILLE, Md., Jan. 8 ... named Lockheed Martin (NYSE: LMT ) an industry ... Operations and Support Services - Unrestricted (BOSS-U) vehicle. As ... selected to participate in this indefinite delivery, indefinite quantity (ID/IQ) ...
... light-based probing techniques at the U.S. Department of Energy,s ... illuminated important details about a class of enzymes involved ... clocks. The interdisciplinary team has a broad ... 1930s and derive from riboflavin, or vitamin B2. These ...
... A group of Dartmouth researchers has found a ... chromosome segregation during cell division. Their finding adds to ... and contributes to understanding how cell function can go ... The researchers studied a protein called NOD, distantly related ...
Cached Biology News:Lockheed Martin Team Wins Role on Key Department of Defense Biometrics Contract Vehicle 2Researchers first to 'see' reactive oxygen species in vital enzyme 2Researchers first to 'see' reactive oxygen species in vital enzyme 3Dartmouth researchers find new protein function 2
Request Info...
... The Gla-type Osteocalcin EIA Kit is ... kit for quantitative determination of human ... cell culture supernatants, and other biological ... research use only. It is not ...
Antibodies were affinity purified using epitopes specific to Alpha4 immobilized on solid support....
in vitro Translation, Accessory Products...
Biology Products: