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Zysis Receives US Patent for Long Acting Oral Aripiprazole Once Weekly


About LAO Aripiprazole Once Weekly

LAO Aripiprazole Once Weekly with medically supervised dosing is intended to reduce relapse rate in the population of schizophrenic and bipolar patients who require approaches to increase adherence but who are not ready yet for the highly invasive and extremely expensive option of the LAIs.  The ability to achieve oral once weekly dosing for aripiprazole comes from a combination of sustained release technologies; long drug plasma half-life; and the very slow disassociation of drug from the D2 receptors in the brain which appears to be unique to this anti-psychotic.   LAO and LAI products are highly synergistic in the market and provide a broader range of options for use in improving adherence, dependent on severity of the condition and relapse history of the patients. 

For further information, please contact:

Dr Peter Cozens, Chairman
Tel: +44-1798-831278

Hume Brophy
Mary Clark, Hollie Vile, Supriya Mathur
Tel: +44-20-3440-5653

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