Navigation Links
ZymoGenetics and Merck Serono Receive FDA Special Protocol Assessment for Atacicept Pivotal Study in Lupus Nephritis
Date:10/4/2007

ients with general systemic lupus erythematosus, for which the SPA review process is ongoing.

About Lupus Nephritis

Lupus nephritis is a complication of systemic lupus erythematosus(SLE) and is characterized by inflammation of the kidneys. Patients with lupus nephritis typically have damage to the glomerulus and progressive loss of kidney function. In the U.S., SLE affects 1 person in 2000, with higher rates among women and among individuals with African, Asian, and Hispanic genetic heritage. Published studies estimate that clinical renal involvement occurs in at least 30% of those with SLE.

About Atacicept

ZymoGenetics and Merck Serono, an affiliate of Merck KGaA, Darmstadt, Germany, are developing atacicept (formerly referred to as TACI-Ig) for the treatment of autoimmune diseases and B-cell malignancies. Atacicept contains the soluble TACI receptor that binds to the cytokines BLyS and APRIL. These cytokines are members of the tumor necrosis factor family that promote B-cell survival and autoantibody production associated with certain autoimmune diseases such as SLE. Current data indicates that levels of BLyS and APRIL are elevated in patients with rheumatoid arthritis, SLE and B-cell malignancies. Atacicept has been shown to affect several stages of B-cell development and may inhibit the survival of cells responsible for making antibodies.

About ZymoGenetics

ZymoGenetics creates novel protein drugs with the potential to significantly help patients fight their diseases. The Company is developing a diverse pipeline of product candidates that are moving into and through clinical development. These candidates span a wide array of clinical opportunities that include bleeding, autoimmune diseases and cancer. ZymoGenetics intends to commercialize these product candidates through internal development, collaborations with partners, and out-licensing of patents from its extensive patent portfolio. For further information, visit

SOURCE ZymoGenetics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. UW-Madison to receive $125M for bioenergy research center
2. Madison to receive funding as part of $60M solar energy program
3. Software exec Jan Eddy to receive "Seize the Day" award
4. Medical College receives $377K to study brain disease
5. Lucigen receives $750K grant to boost biofuel yields
6. Medical College receives $1.4M cancer grant
7. Wisconsin biotech firm receives $107K NIH grant
8. InvivoSciences receives NIH grant for heart technology
9. Nations only stem cell bank will receive UC-San Francisco cell line
10. Medical College receives $11 million grant to study high blood pressure
11. Madison business receives $115,000 of new state biofuels funding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... April 17, 2015  US-Australian drug discovery company, Novogen, ... of Understanding with the Feinstein Institute for Medical ... to collaborate with the objective of ... The collaboration brings together the drug discovery expertise ... of the Feinstein Institute in neurosciences and oncology. ...
(Date:4/17/2015)... LC Sciences LLC, a leading developer ... it is seeking beta testers for the VariantPro™ ... targeted sequencing technology. The system offers cost-effective, minimal ... detection of rare variants. It utilizes novel and ... will collaborate with beta testers to generate test ...
(Date:4/16/2015)... April 17, 2015 Spirax Sarco, ... services, released their newly designed, state-of-the-art website in ... facing website effectively promotes the Spirax Sarco brand, ... the information that a site visitor might be ... company capabilities, industries serviced, the latest company news, ...
(Date:4/16/2015)... CAMBRIDGE, Mass. (PRWEB) April 16, 2015 ... of smart data solutions driven by Semantic Web ... provider of specialist information and services for the ... today announced that its joint solution ‘Smart Data ... named a finalist for the 2015 Bio-IT ‘Best ...
Breaking Biology Technology:Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 2LC Sciences Seeks Beta Testers of Targeted Sequencing Method Ahead of Q4 Launch 3Spirax Sarco website has a new look 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 3
... DNA-Based Test Produces Decisive Result Within Minutes, ... Enigma Diagnostics,the life sciences company developing rapid ... has successfully completed a project,commissioned by the ... a rapid, point-of-care diagnostic system for screening ...
... Nov. 8 Kosan Biosciences,Incorporated (Nasdaq: KOSN ) today ... 30, 2007. Net loss for the quarter and nine ... or $0.26 per share and $0.46 per share,compared to a ... and,$0.76 per share, in the same periods last year. ...
... The Organizations Advocating Use of Hand ... Prevention and Protection, NORCROSS, Ga., Nov. 8 ... and the media continue,to report daily on recent school ... to this drug-resistant staph infection*. Even though,hand-washing is advocated ...
Cached Biology Technology:Enigma Diagnostics to Develop Clinical Diagnostics Platform for UK National Chlamydia Screening Programme 2Enigma Diagnostics to Develop Clinical Diagnostics Platform for UK National Chlamydia Screening Programme 3Kosan Announces Third Quarter 2007 Financial Results 2Kosan Announces Third Quarter 2007 Financial Results 3Kosan Announces Third Quarter 2007 Financial Results 4Kosan Announces Third Quarter 2007 Financial Results 5Kosan Announces Third Quarter 2007 Financial Results 6Kosan Announces Third Quarter 2007 Financial Results 7Soap and Water May not be Enough to Fight MRSA Superbug 2Soap and Water May not be Enough to Fight MRSA Superbug 3
(Date:4/13/2015)... YORK , April 13, 2015 ... by TechSci Research, "Global Biometrics Market Forecast & Opportunities, ... register a CAGR of around 14% till 2020. ... governments for large scale implementation and review of ... and launch of new products with greater efficiency, ...
(Date:4/10/2015)... 2015 Research and Markets ( ... "Security Competitive Profiles - NEC" report to their ... NEC will continue to supply a range of IT ... a company focus on the development of a Big ... opportunities in the Asia-Pacific region ...
(Date:4/8/2015)... 2015  Infinisource, a leading provider of SaaS-based Human ... a leading supplier of biometric identification and security ... most advanced biometrically-enabled time clock, the companies announced ... is setting a bold, new standard for the ... small and mid-size employer. When connected to the ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3
... There,s a wobbly new biochemical structure in Burckhard Seelig,s ... what enzymes looked like billions of years ago, when ... they became ingredients for new and improved products, from ... fledgling enzyme by using directed evolution in the laboratory. ...
... , JUPITER, FL, January 30, 2013 It takes a ... synthesized, neuron structures altered. While some of these memory-building mechanisms ... that a unique group of molecules called microRNAs, known to ... more important role in memory formation than previously thought. ...
... School Team 1 won the Colorado High School Science Bowl ... Bowl in Washington D.C., Apr. 25-29, where they will compete ... 70 high schools. The U.S. Department of Energy (DOE) ... to encourage high school students to explore math and science. ...
Cached Biology News:U. of Minn. researchers unveil first artificial enzyme created by evolution in a test tube 2Scientists uncover previously unknown mechanism of memory formation 2
Cells are grown in triple flasks, roller bottles, or NUNC Factory. Viability and growth curves are generated from a parallel representative culture....
... against a large variety of antigens. ... provided with personalized project proposals and ... by Covance remain exclusive property of ... project has four phases: immunization, fusion, ...
Standard and modified oligonucleotides up to 150 nt-long at any scale for broad applications. Price starts from 30p/base (10 nmole scale)....
... T7Select Packaging Extracts are optimized for maximum ... insert. The high efficiency extracts (> 109 ... to produce a library containing at least ... arms. The extracts are made from a ...
Biology Products: