Navigation Links
YM BioSciences Expands Phase I/II Trial for JAK Inhibitor CYT387
Date:11/18/2010

lopment of a drug that could help these patients," said Dr. Jason Gotlib, Assistant Professor, Department of Medicine (Hematology), Stanford University Medical Center.

CYT387 was granted Orphan Drug Designation by the US FDA in September.

For more information on the CYT387 Phase I/II trial, please go to:
cr="true" href="http://clinicaltrials.gov/ct2/show/NCT00935987?term=cyt387&rank=1">http://clinicaltrials.gov/ct2/show/NCT00935987?term=cyt387&rank=1 Oral Presentation at the 52nd American Society of Hematology Annual Meeting: An oral presentation of the CYT387 Phase I/II results will be delivered by Dr. Pardanani on Monday, December  6, 2010 at 11:15 AM in the Orange County Convention Center, Valencia B/C as part of the session named Myeloproliferative Syndromes: Clinical and Translational Advances in Myeloproliferative Neoplasms. YM will host a conference call following the presentation to discuss the trial results. About YM BioSciences YM BioSciences Inc. is a drug development company advancing three clinical-stage products: CYT387, a small molecule, dual inhibitor of JAK1/JAK2 kinase; nimotuzumab, an EGFR-targeting monoclonal antibody; and CYT997, a potent vascular disrupting agent (VDA).

CYT387 is an orally administered inhibitor of both the JAK1 and JAK2 kinase enzymes, which have been implicated in a number of immune cell disorders including myeloproliferative disorders and inflammatory diseases as well as certain cancers. CYT387 is currently in a Phase I/II trial in myelofibrosis with detailed initial safety and activity data expected at the American Society of Hematology (ASH) meeting in December 2010. Nimotuzumab is a humanized monoclonal antibody targeting EGFR with an enhanced side effect profile. Nimotuzumab is being evaluated in numerous Phase II and III trials worldwide by YM's licensees. CYT997 is an orally-available smal
'/>"/>

SOURCE YM BioSciences Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Ardea Biosciences to Present at Two Upcoming Investor Conferences
2. YM BioSciences Reports Fiscal First Quarter 2011 Operational and Financial Results
3. YM BIOSCIENCES REPORTS SIGNIFICANT RESPONSE RATES IN ANEMIA, SPLENOMEGALY, AND CONSTITUTIONAL SYMPTOMS FROM THE PHASE I/II TRIAL OF ITS JAK1/JAK2 INHIBITOR, CYT387, IN MYELOFIBROSIS
4. Regado Biosciences Awarded Three Grants from the Federal Government to Advance Research of Lead Programs
5. Sangamo BioSciences Awarded Grants for the Development of Four ZFP Therapeutic® Programs
6. Ardea Biosciences Awarded a $733,438 Grant from the U.S. Government Under the Patient Protection and Affordable Care Act
7. X-BODY BioSciences Awarded Grant for Therapeutic Discovery Project Targeting Metastatic Tumor Stem Cells
8. Ardea Biosciences to Present at the Oppenheimer 21st Annual Healthcare Conference
9. Regado Biosciences to Present at the Oppenheimer 21st Annual Healthcare Conference in New York City
10. GeneLink BioSciences, Inc. Ranked 62nd Fastest Growing Company in North America on Deloittes 2010 Technology Fast 500™
11. Sangamo BioSciences Announces Third Quarter 2010 Conference Call and Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... YORK , May 21, 2013  The Lindsley F. ... today that it is a Grand Challenges Explorations ... Gates Foundation .  Dr. Sara Lustigman , ... innovative global health and development research project, titled Innovative ...  These worms are needed to screen drugs to help ...
(Date:5/21/2013)... led by George Washington University Professor Tianshu Li ... in small droplets is strongly size-dependent, an important ... The formation of ice at the nanoscale is ... also has important implications for climate research and ... from supercooled water is generally initiated by a ...
(Date:5/21/2013)... Savoury Systems International (SSI), a leader in ... Southeastern USA Sales Broker. Braddy’s new role will allow ... Southeast. , In 2004 Braddy founded Southeastern ... food processors and industrial manufacturers. Braddy has worked ... and has over 25 years of sales management experience. ...
(Date:5/21/2013)... , May 21, 2013 According ... Research ( http://www.transparencymarketresearch.com ) "Biochip Products and Services Market ... - U.S. Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018," ... 2011 and is expected to grow at a CAGR ... estimated value of USD 4.7 billion in 2018. ...
Breaking Biology Technology:New York Blood Center's Research Institute Receives Grand Challenges Explorations Grant For Groundbreaking Research in Global Health and Development 2New York Blood Center's Research Institute Receives Grand Challenges Explorations Grant For Groundbreaking Research in Global Health and Development 3Study led by GW professor provides better understanding of water's freezing behavior at nanoscale 2The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 2The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 4The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 5
... a contract research and manufacturing organization (CRO/CMO), has been ... exceptional performance in support of Lilly,s strategic objectives."It is ... by such an elite organization and it provides solid ... and superior customer service in the delivery of our ...
... aTyr Pharma Scientific Advisory Board Member Recognized for Development ... Wing Hung Wong, Professor of Statistics and of Health ... been elected to the US National Academy of Sciences. ... one of the highest honors that can be accorded ...
... May 17 Hai Kang Life Corporation Limited ... LOAC (Lab-on-a-Chip) system, EFADchip ... Global Event for Biotechnology held in Atlanta, through ... the largest annual gathering for the biotechnology industry ...
Cached Biology Technology:Professor Wing Wong Elected to the National Academy of Sciences 2A New Era in the Application of Lab-on-a-Chip to Rapid Point-of-Care Diagnosis 2A New Era in the Application of Lab-on-a-Chip to Rapid Point-of-Care Diagnosis 3
(Date:5/20/2013)... Geology articles posted online ahead of ... wide swath of geoscience subdisciplines, including minerals exploration, ... Locations studied include Siberia; the Sumatran subduction margin; ... Ukraine; Mars; and the Southeastern U.S. Atlantic Margin. ... and plate tectonics;, 2. The clear fingerprint of ...
(Date:5/19/2013)... the University of California, Davis have engineered a strain ... light. They report their findings today at the ... , "In this work, we used synthetic biology approaches ... dioxide and light energy for growth) cyanobacterial metabolism for ... McEwen, the lead researcher on the study. He ...
(Date:5/18/2013)... FL (May 18, 2013) Research presented at ... managing digestive health through diet and lifestyle. ... plagued by reduced muscle strength, fatigue and poor ... when patients are in remission. A randomized, double ... that vitamin D supplementation corresponded to significant relief ...
Breaking Biology News(10 mins):New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 3New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 4New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 5New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 6New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 7New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 8New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 9New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 10New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 11Research examines new methods for managing digestive health 2Research examines new methods for managing digestive health 3
... Clinic and Riverain Medical today announced the establishment of ... whether chest X-ray CAD (computer-aided detection) can improve practical ... designed to determine whether chest X-ray CAD can help ... stage when they are most treatable, leading to improved ...
... 2003, Europes first Mars orbiter arrived at the Red ... rewrite the text books as its instruments send back ... spacecraft reached another milestone in its remarkable career by ... to investigate martian mysteries, the orbiter has revolutionised our ...
... the human immunodeficiency virus (HIV-1) molecular machinery responsible ... to a study by investigators at the University ... (AVRC), published November 23 in PLoS Computational Biology. ... adaptability of HIV-1 has so far foiled the ...
Cached Biology News:Cleveland Clinic leading clinical program to improve early-stage lung cancer detection 2Mars Express -- 5000 orbits and counting 2Mars Express -- 5000 orbits and counting 3
... The VSOS-4 Orbital Shaker is designed to ... provide a uniform motion that is both mixing ... VSOS-4 Orbital Shaker provides a smooth, quiet, reproducible ... a wide range of laboratory applications such as ...
... FastPlax Titer Kit is designed for determination of ... 46 days as in other methods. Classical determination ... of plaques, but the FastPlax Kit takes advantage ... gp64 glycoprotein on the cell surface as early ...
... EVOware is Tecans state-of-the-art software for all ... and scheduling in a single, scalable software ... and consistent, simplifying the control of all ... a Freedom EVO 100 with one liquid ...
... Kit is an advanced system for isolating DNA from ... be used directly for any downstream application. ... to use in 56 minutes Low melting point ... and TBE gels No specialised equipment required ...
Biology Products: