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YM BIOSCIENCES ANNOUNCES PRESENTATIONS FOR TWO OF ITS ANTI-CANCER DRUGS AT AACR ANNUAL MEETING
Date:4/11/2008

of necrosis, suggesting that tesmilifene may induce necrotic death in drug-resistant tumour cells. Genomic studies have shown that two tesmilifene-dependent genes in MCF-7(DOX-2) cells were found to be related to lysosome function.

"This is an important finding suggesting that tesmilifene can target cells that are normally resistant to chemotherapy and may have clinical utility in treating patients with refractory/chemotherapy resistant tumors," said David Allan, Chairman and CEO of YM BioSciences. "YM previously announced termination of clinical development of tesmilifene, however, academic work focused on determining the mechanism of action of this unique molecule continues in order to support potential partnering opportunities."

About YM BioSciences

YM BioSciences Inc. is an oncology company that identifies, develops and commercializes differentiated products for patients worldwide. The Company has two late-stage products: nimotuzumab, a humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR) and is approved in several countries for treatment of various types of head and neck cancer; and AeroLEF(TM), a proprietary, inhaled-delivery composition of free and liposome-encapsulated fentanyl in development for the treatment of moderate to severe pain, including cancer pain.

This press release may contain forward-looking statements, which reflect the Company's current expectation regarding future events. These forward-looking statements involve risks and uncertainties that may cause actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements. Such factors include, but are not limited to, changing market conditions, the successful and timely completion of clinical studies, the establishment of corporate alliances, the impact of competitive products and pricing, new product development, uncertainties rela
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SOURCE YM BioSciences Inc.
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