YM BIOSCIENCES ANNOUNCES NIMOTUZUMAB RESULTS IN ADVANCED TRIPLE-NEGATIVE BREAST CANCER MODEL PRESENTED AT AACR-NCI-EOR... ( MISSISSAUGA ON Nov. 18 / YM BioScie...)

HOME >> BIOLOGY >> TECHNOLOGY

YM BIOSCIENCES ANNOUNCES NIMOTUZUMAB RESULTS IN ADVANCED TRIPLE-NEGATIVE BREAST CANCER MODEL PRESENTED AT AACR-NCI-EORTC MEETING

Date:11/18/2009

MISSISSAUGA, ON, Nov. 18 /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: YMI; TSX: YM), a life sciences product development company that identifies and advances a diverse portfolio of promising cancer-related products at various stages of development, announced that results from a study evaluating nimotuzumab were presented today in a poster at the 2009 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics conference in Boston, Massachusetts. The reported results demonstrate that nimotuzumab in combination with metronomic chemotherapy in an advanced triple-negative breast cancer preclinical model is safe and effective.

In this study nimotuzumab, an epidermal growth factor receptor (EGFR) targeting antibody, was administered twice weekly in combination with metronomic (continuous low-dose) cyclophosphamide. This regimen resulted in significant primary tumor growth delay in an aggressive, metastatic, higher EGFR-expressing variant of the MDA-MB-231 human breast cancer breast model, which over-expresses EGFR. In addition, the combination resulted in a significant survival advantage over cyclophosphamide alone.

"The data demonstrate that nimotuzumab in combination with metronomic cyclophosphamide is safe and effective in this aggressive tumor type which has limited therapeutic options. Furthermore, the addition of nimotuzumab would be expected to be minimally toxic to patients and as such, this combination should be considered for this patient population in future clinical trials," said lead author Dr. Anthony J. Mutsaers of the Division of Molecular and Cellular Biology Research, Sunnybrook Health Sciences Centre and Department of Medical Biophysics, University of Toronto.

The research poster is entitled "Combination treatment with metronomic cyclophosphamide and the EGFR monoclonal antibody nim
'/>"/>

SOURCE YM BioSciences Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3
Related biology technology :

1. Regado Biosciences to Present at the Lazard Capital Markets 6th Annual Healthcare Conference on November 17, 2009
2. YM BIOSCIENCES REPORTS FISCAL FIRST QUARTER 2010 OPERATIONAL AND FINANCIAL RESULTS
3. Regado Biosciences to Present at the Ninth Annual Joint Symposium of BioNJ and Pennsylvania Bio on November 16, 2009
4. Sangamo BioSciences Announces Presentation at Merriman Curhan Fords Investor Summit 2009
5. YM BIOSCIENCES REPORTS POSITIVE NIMOTUZUMAB FOUR-YEAR SURVIVAL DATA PRESENTED AT ASTRO 2009
6. YM BIOSCIENCES REPORTS ADDITIONAL RESULTS FROM NIMOTUZUMAB PHASE III STUDY IN CHILDREN WITH GLIOMA PRESENTED BY ONCOSCIENCE AG
7. Sangamo BioSciences Announces Third Quarter 2009 Conference Call and Webcast
8. OriGene Technologies Acquires Marligen Biosciences
9. Cytopia Merger with Toronto-based YM BioSciences Inc.
10. YM BIOSCIENCES ANNOUNCES OFFER FOR CYTOPIA LTD., AN AUSTRALIAN CANCER-FOCUSED DEVELOPMENT COMPANY
11. Regado Biosciences To Present at the 2009 Japan Biopharma Partnering Conference on October 6, 2009

Post Your Comments:

(Date:5/23/2013)... 23, 2013 The New Jersey chapter ... Black Data Processing Associates (BDPA), is hosting its 10th ... 2013. This all-day event will encourage students and their ... ins and outs from many of the industries’ finest ... the New Jersey Institute of Technology, the event will ...

(Date:5/23/2013)... 2013 Pusan National University Yangsan Hospital, ... and contract research company focused on research and ... today a publication reporting the induction of functional ... and immunotherapeutic vaccinia JX-594 (pexastimogene devacirepvec; Jennerex Inc.). ... the May 15 th , 2013 issue of ...

(Date:5/23/2013)... Bed bugs compromised Penn State. A report ... Meanwhile, My Cleaning Products offered complimentary samples of its bed ... without using harmful chemical elements. , Based on the ... building was actually a dormitory , My Cleaning Products ... May 13 and bed bug presence was confirmed on May ...

(Date:5/22/2013)... Oven Industries announces the new 5R1-1400 AC ... a PC through the TTL level UART Communication port. ... square can deliver up to 15 AMPS of load ... state relay. Operator safety is achieved with 1KV of ... sensor input. Specifications: Input Voltage 85 to 265VAC ...

Breaking Biology Technology:Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2 Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 2 Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment 3 Penn State Dorm Infested with Bed Bugs, My Cleaning Products Offers Complimentary Sample of Bed Bug Spray to Help Bed Bug Victims 2 New AC Temperature Controller Announced by Oven Industries 2

[0] Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 [0] Pusan National University Announces Science Translational Medicine Publication Highlighting Landmark Demonstration of Functional Anti-Cancer Antibody Induction in Patients Following JX-594 Treatment [0] Penn State Dorm Infested with Bed Bugs, My Cleaning Products Offers Complimentary Sample of Bed Bug Spray to Help Bed Bug Victims [0] New AC Temperature Controller Announced by Oven Industries

... , , ... ... ... ...

... in the understanding of how specific types of tissue are ... has succeeded in mapping the entire network of DNA-binding transcription ... which factors can combine to determine cell fate, will be ... Cell . Transcription factors (TFs) are proteins that bind ...

... N.Y. Determined to play a key role in ... doctoral student in the Department of Mechanical, Aerospace, and ... new method for storing hydrogen at room temperature. ... graphene that exhibits hydrogen storing capacity far exceeding any ...

China Cord Blood Corporation Reports Financial Results for Third Quarter and First Nine Months of Fiscal 2010 Researchers create atlas of transcription factor combinations Helping hydrogen: Student inventor tackles challenge of hydrogen storage

(Date:5/23/2013)... in treating cerebral palsy with autologous cord blood. Following ... year old boy had been in a persistent vegetative ... months after treatment with the cord blood containing stem ... the child learned to speak simple sentences and to ... study, dispel the long-held doubts about the effectiveness of ...

(Date:5/22/2013)... 22, 2013 U.S. Forest Service scientists are part ... funding from the TKF Foundation, will examine how collaborative ... individuals recover from tragedy. , The TKF Foundation announced ... projects selected for grant funding. In addition to research ... in recovery and resiliency, the 3-year, $585,000 grant will ...

(Date:5/22/2013)... fatty acids in fish oil have long been thought ... American Heart Association currently recommends eating at least two ... in omega 3s. However, the mechanism behind this protective ... scientists led by Jason R. Carter of Michigan Technological ... that fish oil might specifically counteract the detrimental effects ...

Breaking Biology News(10 mins):First successful treatment of pediatric cerebral palsy with autologous cord blood 2 'Landscapes of Resilience' to study how people use nature as a source of recovery 2 Fish oil may help the heart beat mental stress 2

[0] First successful treatment of pediatric cerebral palsy with autologous cord blood [0] 'Landscapes of Resilience' to study how people use nature as a source of recovery [1] Fish oil may help the heart beat mental stress

... , LAKE MARY, Fla. , April 26 Roundtable Concepts ... are of the highest quality components and specifications. A great review has been ... limited time only, is offering this promotional special: the RTC View 32" LCD ... at www.rtcview.com . , , ...

... Innovalight, Inc., a privately-held firm selling a platform of silicon ink-based ... company has achieved a new record of 19 percent conversion efficiency ... solar cell is the proportion of sunlight energy that a cell ... , , ...

... faculty members at the University of California, Riverside ... have been awarded 2010 Guggenheim Fellowships by ... Guggenheim Fellows are appointed on the basis of achievement ... the fellowship for genetics, genomics, and the many faces ...

Cached Biology News:Roundtable Concepts Inc., the Company that has Officially Licensed Marvel Comic TVs and Officially Licensed Collegiate TVs, has just Launched their Own Line of HDTVs Named RTC View 2 Innovalight Establishes New Record With Silicon Ink Solar Cells 2 Innovalight Establishes New Record With Silicon Ink Solar Cells 3 2 professors at UC Riverside receive Guggenheim Fellowships 2 2 professors at UC Riverside receive Guggenheim Fellowships 3

Roundtable Concepts Inc., the Company that has Officially Licensed Marvel Comic TVs and Officially Licensed Collegiate TVs, has just Launched their Own Line of HDTVs Named RTC View Innovalight Establishes New Record With Silicon Ink Solar Cells 2 professors at UC Riverside receive Guggenheim Fellowships

... from Magnetofection technology, SilenceMag is the ... Simple, rapid and easy to use, ... toxic. Specifically designed for siRNA delivery, ... very low doses of siRNA.,SilenceMag formulation ...

... Radiolabeled Ligands\n\nReceptor-related research has long been enabled ... ligands selected to keep pace with new ... products and services for receptor research and ... If you do not find exactly what ...

... The Fluorescence Test Plate consists of ... format, with Inert Organic Fluorescent Compounds embedded ... be used on BioTeks FLx800 and Synergy ... ideal for GLP compliance while reducing the ...

... Extraction Software reads and processes ... prepare microarray data for analysis. ... one 2-year license for ... accounts , * one ...

Biology Products:

Magnetofection - SilenceMag from OZ Biosciences Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer Fluorescence Test Plate from BioTek Instruments Feature Extraction Software; 2-year License for Not-For-Profit/Academic from Agilent Technologies